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Keywords: ADP
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Clin Sci (Lond) (2010) 118 (7): 459–461.
Published: 12 January 2010
... on vascular contraction/vasodilation via direct or indirect mechanisms, Giachini et al. [ 7 ] studied the effect of a P2Y 12 agonist 2-MeS-ADP (2-methylthio-ADP). They showed that 2-MeS-ADP induced endothelium-dependent relaxation and vasoconstriction to the same degree in both vehicle and AngII-infused rats...
Clin Sci (Lond) (2010) 118 (7): 463–471.
Published: 12 January 2010
...±2.8) in AngII-treated animals. Vascular expression of P2Y 12 receptor was determined by Western blot. Pharmacological characterization of vascular P2Y 12 was performed with the P2Y 12 agonist 2-MeS-ADP [2-(methylthio) adenosine 5′-trihydrogen diphosphate trisodium]. Although 2-MeS-ADP induced...
Clin Sci (Lond) (1994) 87 (5): 575–580.
Published: 01 November 1994
...Nicolas A. F. Chronos; Darren J. Wilson; Sarah L. Janes; Ronald A. Hutton; Nigel P. Buller; Alison H. Goodall 1. Aspirin inhibits the conversion of arachidonic acid to thromboxane A 2 which reinforces the effects of weak agonists such as ADP in platelets. 2. In this study the effect of aspirin (300...