... and inhibited by vitamin E (VE) (α-tocopherol) administration. Therefore, the present study aimed at assessing lipid metabolism in the gastric mucosa and ethanol-induced gastric damage and the effect of α-tocopherol administration. For this, rates of fatty acid β-oxidation and lipogenesis were tested in gastric...

... NAFLD. As a consequence of increased PPAR-γ expression, there is also a secondary induction of key enzymes involved in mitochondrial β-oxidation and, interestingly, Piguet et al. [ 2 ] show a hypoxia-induced increase in HIF-2α (hypoxia-induced factor-2α), with translocation of HIF-2α to the nucleus...

... tolerance were measured in blood. Histological lesions were quantified. Expression of genes involved in lipogenesis and mitochondrial β-oxidation, as well as FOXO1 (forkhead box O1), hepcidin and CYP2E1 (cytochrome P450 2E1), were analysed by quantitative PCR. In the animals exposed to hypoxia...

...S. Eaton; A. M. Zaitoun; C. O. Record; K. Bartlett 1. The CoA and carnitine ester intermediates of mitochondrial β-oxidation have not previously been quantified in liver disease, although there is some evidence that β-oxidation is inhibited in alcoholic fatty liver. Mitochondria were isolated from...