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Articles

Assessing hypothalamic pituitary gonadal function in reproductive disorders

Kanyada Koysombat, Waljit S. Dhillo, Ali Abbara
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (11): 863–879.
DOI: https://doi.org/10.1042/CS20220146
Published: 05 June 2023
View article titled, Assessing hypothalamic pituitary gonadal function in reproductive disorders
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Articles

NPFFR2-deficient mice fed a high-fat diet develop strong intolerance to glucose

Alena Karnošová, Veronika Strnadová, Blanka Železná, Jaroslav Kuneš, Petr Kašpárek, Lenka Maletínská
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (10): 847–862.
DOI: https://doi.org/10.1042/CS20220880
Published: 31 May 2023
View article titled, NPFFR2-deficient mice fed a high-fat diet develop strong intolerance to glucose
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Includes: Supplementary data
Articles

Akt2 deficiency alleviates oxidative stress in the heart and liver via up-regulating SIRT6 during high-fat diet-induced obesity

Weixian Kong, Yue Peng, Caoyu Ji, Zekun Liu, Shuya Gao, Yuexin Zhang, Jiawen Chen, Xie Li, Mengmeng Bao, Yubin Zhang, Qizhou Jiang, Fuqun Wang, Zhe Li, Xiaohong Bian, Junmei Ye
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (10): 823–841.
DOI: https://doi.org/10.1042/CS20230433
Published: 31 May 2023
View article titled, Akt2 deficiency alleviates oxidative stress in the heart and liver via up-regulating SIRT6 during high-fat diet-induced obesity
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Includes: Supplementary data
Articles

Essential metabolism required for T and B lymphocyte functions: an update

Vinicius Leonardo Sousa Diniz, Anuska Marcelino Alvares-Saraiva, Tamires Duarte Afonso Serdan, Laiane Cristina dos Santos-Oliveira, Vinicius Cruzat, Tiago Bertola Lobato, Richelieau Manoel, Amanda Lins Alecrim, Otavio Augusto Machado, Sandro M. Hirabara, Laureane Nunes Masi, Tania Cristina Pithon-Curi, Rui Curi, Renata Gorjão, Philip Newsholme
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (10): 807–821.
DOI: https://doi.org/10.1042/CS20220869
Published: 23 May 2023
View article titled, Essential metabolism required for T and B lymphocyte functions: an update
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Articles

Revisiting blood pressure and body fluid status

Kento Kitada, Akira Nishiyama
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (9): 755–767.
DOI: https://doi.org/10.1042/CS20220500
Published: 18 May 2023
View article titled, Revisiting blood pressure and body fluid status
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Articles

The role of hormones in sepsis: an integrated overview with a focus on mitochondrial and immune cell dysfunction

Miranda J. Melis, Muska Miller, Vera B.M. Peters, Mervyn Singer
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (9): 707–725.
DOI: https://doi.org/10.1042/CS20220709
Published: 05 May 2023
View article titled, The role of hormones in sepsis: an integrated overview with a focus on mitochondrial and immune cell dysfunction
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Articles

Increased methylglyoxal formation in plasma and tissues during a glucose tolerance test is derived from exogenous glucose

Xiaodi Zhang, Jean L.J.M. Scheijen, Coen D.A. Stehouwer, Kristiaan Wouters, Casper G. Schalkwijk
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (8): 697–706.
DOI: https://doi.org/10.1042/CS20220753
Published: 26 April 2023
View article titled, Increased methylglyoxal formation in plasma and tissues during a glucose tolerance test is derived from exogenous glucose
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Includes: Supplementary data
Articles

Flavonoid derivative DMXAA attenuates cisplatin-induced acute kidney injury independent of STING signaling

Lingling Lu, Weihua Liu, Shumin Li, Mi Bai, Yu Zhou, Zhaohui Jiang, Zhanjun Jia, Songming Huang, Aihua Zhang, Wei Gong
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (6): 435–452.
DOI: https://doi.org/10.1042/CS20220728
Published: 21 March 2023
View article titled, Flavonoid derivative DMXAA attenuates cisplatin-induced acute kidney injury independent of STING signaling
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Includes: Supplementary data
Articles

Hormonal regulation of metabolism—recent lessons learned from insulin and estrogen

Zhipeng Tao, Zhiyong Cheng
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (6): 415–434.
DOI: https://doi.org/10.1042/CS20210519
Published: 21 March 2023
View article titled, Hormonal regulation of metabolism—recent lessons learned from insulin and estrogen
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Articles

Down-regulation of ALDOB during metabolic reprogramming mediates malignant behavior in hepatocellular carcinoma and insensitivity to postoperative adjuvant transarterial chemoembolization

Jing-Xuan Xu, Shui-Lin Qin, Hao-Wen Wei, Yuan-Yuan Chen, Yu-Chong Peng, Lu-Nan Qi
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (4): 303–316.
DOI: https://doi.org/10.1042/CS20220661
Published: 17 February 2023
View article titled, Down-regulation of ALDOB during metabolic reprogramming mediates malignant behavior in hepatocellular carcinoma and insensitivity to postoperative adjuvant transarterial chemoembolization
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Includes: Supplementary data
Articles

The tendency of anemia of inflammation in periodontal diseases

Ye Han, Zhiqiang Luo, Zhao Guo Yue, Li Li Miao, Min Xv, Shu Chang, Yalin Zhan, Jianxia Hou
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (3): 251–264.
DOI: https://doi.org/10.1042/CS20220524
Published: 08 February 2023
View article titled, The tendency of anemia of inflammation in periodontal diseases
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Includes: Supplementary data
Articles

Iron and mitochondria in the susceptibility, pathogenesis and progression of COPD

Lynne Faherty, Sarah Kenny, Suzanne M. Cloonan
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (3): 219–237.
DOI: https://doi.org/10.1042/CS20210504
Published: 02 February 2023
View article titled, Iron and mitochondria in the susceptibility, pathogenesis and progression of COPD
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Articles

The membrane-associated protein 17 (MAP17) is up-regulated in response to empagliflozin on top of RAS blockade in experimental diabetic nephropathy

Ander Vergara, Carmen Llorens-Cebrià, Nerea Martos, Irene Martínez-Díaz, Frank Stein, Pamela Domínguez-Báez, Mireia Molina-Van den Bosch, Mandy Rettel, Begoña Benito, Sheila Bermejo, Michael Paul Pieper, Conxita Jacobs-Cachá, Maria José Soler
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (1): 87–104.
DOI: https://doi.org/10.1042/CS20220447
Published: 05 January 2023
View article titled, The membrane-associated protein 17 (MAP17) is up-regulated in response to empagliflozin on top of RAS blockade in experimental diabetic nephropathy
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Includes: Supplementary data
Articles

Biological tuners to reshape the bile acid pool for therapeutic purposes in non-alcoholic fatty liver disease

Justine Gillard, Isabelle A. Leclercq
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (1): 65–85.
DOI: https://doi.org/10.1042/CS20220697
Published: 05 January 2023
View article titled, Biological tuners to reshape the bile acid pool for therapeutic purposes in non-alcoholic fatty liver disease
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Articles

The importance of placental lipid metabolism across gestation in obese and non-obese pregnancies

In Collection
Reproductive Physiology and Disease
Kyle M. Siemers, Michelle L. Baack
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (1): 31–34.
DOI: https://doi.org/10.1042/CS20220657
Published: 03 January 2023
View article titled, The importance of placental lipid metabolism across gestation in obese and non-obese pregnancies
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Articles

Structural functionality of skeletal muscle mitochondria and its correlation with metabolic diseases

Gourabamani Swalsingh, Punyadhara Pani, Naresh C. Bal
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (24): 1851–1871.
DOI: https://doi.org/10.1042/CS20220636
Published: 22 December 2022
View article titled, Structural functionality of skeletal muscle mitochondria and its correlation with metabolic diseases
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Articles

The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models

Aliye Uc, Birgitta Strandvik, Jianrong Yao, Xiaoming Liu, Yaling Yi, Xingshen Sun, Ruth Welti, John F. Engelhardt, Andrew W. Norris
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (24): 1773–1791.
DOI: https://doi.org/10.1042/CS20220450
Published: 13 December 2022
View article titled, The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models
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Includes: Supplementary data
Articles

Metformin alleviates HFD-induced oxidative stress in hepatocyte via activating SIRT6/PGC-1α/ENDOG signaling

Shuya Gao, Qingchen Yang, Zekun Liu, Weixian Kong, Jiawen Chen, Xie Li, Yue Peng, Mengmeng Bao, Xiaohong Bian, Yuexin Zhang, Qizhou Jiang, Zhe Li, Yubin Zhang, Fangrong Yan, Junmei Ye
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (22): 1711–1730.
DOI: https://doi.org/10.1042/CS20220242
Published: 30 November 2022
View article titled, Metformin alleviates HFD-induced oxidative stress in hepatocyte via activating SIRT6/PGC-1α/ENDOG signaling
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Includes: Supplementary data
Articles

A novel technique using chronic infusion of small extracellular vesicles from gestational diabetes mellitus causes glucose intolerance in pregnant mice

In Collection
Reproductive Physiology and Disease
Laura B James-Allan, Frederick J Rosario, Lana Madi, Kelsey Barner, Soumyalekshmi Nair, Andrew Lai, Flavio Carrion, Theresa L Powell, Carlos Salomon, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (21): 1535–1549.
DOI: https://doi.org/10.1042/CS20220484
Published: 03 November 2022
View article titled, A novel technique using chronic infusion of small extracellular vesicles from gestational diabetes mellitus causes glucose intolerance in pregnant mice
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Includes: Supplementary data
Articles

Measuring muscle protein synthesis in humans and the influence of nutritional state

Philip C. Calder, Nicolaas E.P. Deutz
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (19): 1425–1431.
DOI: https://doi.org/10.1042/CS20211171
Published: 14 October 2022
View article titled, Measuring muscle protein synthesis in humans and the influence of nutritional state
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Articles

Human placental lipid content and lipid metabolic enzyme abundance in obesity and across gestation

In Collection
Reproductive Physiology and Disease
Katie L. Bidne, Charis Uhlson, Claire Palmer, Karin Zemski-Berry, Theresa L. Powell
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (19): 1389–1404.
DOI: https://doi.org/10.1042/CS20220479
Published: 04 October 2022
View article titled, Human placental lipid content and lipid metabolic enzyme abundance in obesity and across gestation
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Includes: Supplementary data
Articles

Severe psychiatric disorders and general medical comorbidities: inflammation-related mechanisms and therapeutic opportunities

Antonio L. Teixeira, Lais B. Martins, Michael Berk, Moisés E. Bauer
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (17): 1257–1280.
DOI: https://doi.org/10.1042/CS20211106
Published: 05 September 2022
View article titled, Severe psychiatric disorders and general medical comorbidities: inflammation-related mechanisms and therapeutic opportunities
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Articles

Targeting skeletal muscle mitochondrial health in obesity

Chantal A. Pileggi, Breana G. Hooks, Ruth McPherson, Robert R.M. Dent, Mary-Ellen Harper
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (14): 1081–1110.
DOI: https://doi.org/10.1042/CS20210506
Published: 27 July 2022
View article titled, Targeting skeletal muscle mitochondrial health in obesity
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Articles

Early biochemical observations point to nutritional strategies to manage non-alcoholic fatty liver disease

Philip C. Calder
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (13): 1019–1023.
DOI: https://doi.org/10.1042/CS20220380
Published: 01 July 2022
View article titled, Early biochemical observations point to nutritional strategies to manage non-alcoholic fatty liver disease
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Articles

Novel insights in endocrine and metabolic pathways in sepsis and gaps for future research

Arno Téblick, Jan Gunst, Lies Langouche, Greet Van den Berghe
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (11): 861–878.
DOI: https://doi.org/10.1042/CS20211003
Published: 01 June 2022
View article titled, Novel insights in endocrine and metabolic pathways in sepsis and gaps for future research
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Articles

Utility of preclinical models of altered maternal nutrition to support the developmental origins of health and disease hypothesis

Mark Hedley Vickers
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (10): 711–714.
DOI: https://doi.org/10.1042/CS20211175
Published: 16 May 2022
View article titled, Utility of preclinical models of altered maternal nutrition to support the developmental origins of health and disease hypothesis
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Articles

Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease

Eva Maria Pastor Arroyo, Nima Yassini, Elif Sakiri, Giancarlo Russo, Soline Bourgeois, Nilufar Mohebbi, Kerstin Amann, Nicole Joller, Carsten A. Wagner, Pedro Henrique Imenez Silva
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (8): 557–577.
DOI: https://doi.org/10.1042/CS20220095
Published: 21 April 2022
View article titled, Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease
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Includes: Supplementary data
Articles

The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer

Richard Cunningham, Carsten Gram Hansen
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (3): 197–222.
DOI: https://doi.org/10.1042/CS20201474
Published: 04 February 2022
View article titled, The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer
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Articles

Augmented CCL5/CCR5 signaling in brown adipose tissue inhibits adaptive thermogenesis and worsens insulin resistance in obesity

Pei-Chi Chan, Li-Man Hung, Jiung-Pang Huang, Yuan-Ji Day, Chao-Lan Yu, Feng-Chih Kuo, Chieh-Hua Lu, Yu-Feng Tian, Po-Shiuan Hsieh
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (1): 121–137.
DOI: https://doi.org/10.1042/CS20210959
Published: 07 January 2022
View article titled, Augmented CCL5/CCR5 signaling in brown adipose tissue inhibits adaptive thermogenesis and worsens insulin resistance in obesity
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Includes: Supplementary data
Articles

Erythrocytes increase endogenous sphingosine 1-phosphate levels as an adaptive response to SARS-CoV-2 infection

In Collection
Coronavirus
Martin Sebastian Winkler, Ralf Alexander Claus, Mareike Schilder, Stefan Pöhlmann, Sina M. Coldewey, Julian Grundmann, Torben Fricke, Onnen Moerer, Konrad Meissner, Michael Bauer, Heike Hofmann-Winkler, Markus H. Gräler
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (24): 2781–2791.
DOI: https://doi.org/10.1042/CS20210666
Published: 22 December 2021
View article titled, Erythrocytes increase endogenous sphingosine 1-phosphate levels as an adaptive response to SARS-CoV-2 infection
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Articles

Asthma and obesity: endotoxin another insult to add to injury?

Nikita Lad, Alice M. Murphy, Cristina Parenti, Carl P. Nelson, Neil C. Williams, Graham R. Sharpe, Philip G. McTernan
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (24): 2729–2748.
DOI: https://doi.org/10.1042/CS20210790
Published: 17 December 2021
View article titled, Asthma and obesity: endotoxin another insult to add to injury?
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Articles

Sex differences in white adipose tissue expansion: emerging molecular mechanisms

Simon T. Bond, Anna C. Calkin, Brian G. Drew
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (24): 2691–2708.
DOI: https://doi.org/10.1042/CS20210086
Published: 15 December 2021
View article titled, Sex differences in white adipose tissue expansion: emerging molecular mechanisms
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Articles

Chronic pharmacological antagonism of the GM-CSF receptor in mice does not replicate the pulmonary alveolar proteinosis phenotype but does alter lung surfactant turnover

Dominic J. Corkill, Alan N. Hunt, Mary Jane Hinrichs, Nicholas White, Marlon Rebelatto, Lorin Roskos, Josquin Nys, Alison Scott, Matthew J. Robinson, Patricia Ryan, Anthony D. Postle, Matthew A. Sleeman
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (22): 2559–2573.
DOI: https://doi.org/10.1042/CS20210713
Published: 26 November 2021
View article titled, Chronic pharmacological antagonism of the GM-CSF receptor in mice does not replicate the pulmonary alveolar proteinosis phenotype but does alter lung surfactant turnover
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Includes: Supplementary data
Articles

Chronic activation of AMP-activated protein kinase leads to early-onset polycystic kidney phenotype

Laura Wilson, Alice E. Pollard, Lucy Penfold, Phillip J. Muckett, Chad Whilding, Mohammad Bohlooly-Y., Patricia Wilson, David Carling
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (20): 2393–2408.
DOI: https://doi.org/10.1042/CS20210821
Published: 22 October 2021
View article titled, Chronic activation of AMP-activated protein kinase leads to early-onset polycystic kidney phenotype
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Includes: Supplementary data
Articles

Selective HIF stabilization alleviates hepatocellular steatosis and ballooning in a rodent model of 70% liver resection

Samuele Iesari, Isabelle Leclercq, Nicolas Joudiou, Mina Komuta, Aurélie Daumerie, Jérôme Ambroise, Alexandra Dili, Natacha Feza-Bingi, Daela Xhema, Caroline Bouzin, Bernard Gallez, Francesco Pisani, Eliano Bonaccorsi-Riani, Pierre Gianello
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (19): 2285–2305.
DOI: https://doi.org/10.1042/CS20210183
Published: 13 October 2021
View article titled, Selective HIF stabilization alleviates hepatocellular steatosis and ballooning in a rodent model of 70% liver resection
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Includes: Supplementary data
Articles

Lipotoxicity: a driver of heart failure with preserved ejection fraction?

Jennifer Leggat, Guillaume Bidault, Antonio Vidal-Puig
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (19): 2265–2283.
DOI: https://doi.org/10.1042/CS20210127
Published: 13 October 2021
View article titled, Lipotoxicity: a driver of heart failure with preserved ejection fraction?
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Articles

Exposure to cigarette smoke precipitates simple hepatosteatosis to NASH in high-fat diet fed mice by inducing oxidative stress

Sherouk Fouda, Anwar Khan, Stanley M.H. Chan, Ali Mahzari, Xiu Zhou, Cheng Xue Qin, Ross Vlahos, Ji-Ming Ye
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (17): 2103–2119.
DOI: https://doi.org/10.1042/CS20210628
Published: 06 September 2021
View article titled, Exposure to cigarette smoke precipitates simple hepatosteatosis to NASH in high-fat diet fed mice by inducing oxidative stress
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Includes: Supplementary data
Articles

Maternal intermittent fasting during pregnancy: a translational research challenge for an important clinical scenario

Dominique Darmaun
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (17): 2099–2102.
DOI: https://doi.org/10.1042/CS20210578
Published: 01 September 2021
View article titled, Maternal intermittent fasting during pregnancy: a translational research challenge for an important clinical scenario
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Articles

Placenta-specific Slc38a2 /SNAT2 knockdown causes fetal growth restriction in mice

Owen R. Vaughan, Katarzyna Maksym, Elena Silva, Kenneth Barentsen, Russel V. Anthony, Thomas L. Brown, Sara L. Hillman, Rebecca Spencer, Anna L. David, Fredrick J. Rosario, Theresa L. Powell, Thomas Jansson
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (17): 2049–2066.
DOI: https://doi.org/10.1042/CS20210575
Published: 31 August 2021
View article titled, Placenta-specific Slc38a2 /SNAT2 knockdown causes fetal growth restriction in mice
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Includes: Supplementary data
Articles

Unravelling the impact of intrauterine growth restriction on heart development: insights into mitochondria and sexual dimorphism from a non-hominoid primate

George W. Booz, Gaelle P. Massoud, Raffaele Altara, Fouad A. Zouein
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (14): 1767–1772.
DOI: https://doi.org/10.1042/CS20210524
Published: 27 July 2021
View article titled, Unravelling the impact of intrauterine growth restriction on heart development: insights into mitochondria and sexual dimorphism from a non-hominoid primate
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Articles

Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability

Mengqiu Wu, Weiyi Chen, Mengqiu Miao, Qianqian Jin, Shengnan Zhang, Mi Bai, Jiaojiao Fan, Yue Zhang, Aihua Zhang, Zhanjun Jia, Songming Huang
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (14): 1707–1726.
DOI: https://doi.org/10.1042/CS20210100
Published: 22 July 2021
View article titled, Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability
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Includes: Supplementary data
Articles

Phosphate and fibroblast growth factor 23 in diabetes

Amarens van der Vaart, Stanley M.H. Yeung, Peter R. van Dijk, Stephan J.L. Bakker, Martin H. de Borst
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (14): 1669–1687.
DOI: https://doi.org/10.1042/CS20201290
Published: 20 July 2021
View article titled, Phosphate and fibroblast growth factor 23 in diabetes
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Articles

Nutrient regulation of inflammatory signalling in obesity and vascular disease

Timothy M. Palmer, Ian P. Salt
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (13): 1563–1590.
DOI: https://doi.org/10.1042/CS20190768
Published: 07 July 2021
View article titled, Nutrient regulation of inflammatory signalling in obesity and vascular disease
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Articles

Cholesterol metabolism: a new molecular switch to control inflammation

Diana Cardoso, Esperanza Perucha
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (11): 1389–1408.
DOI: https://doi.org/10.1042/CS20201394
Published: 04 June 2021
View article titled, Cholesterol metabolism: a new molecular switch to control inflammation
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Articles

A biomimetic natural sciences approach to understanding the mechanisms of ageing in burden of lifestyle diseases

Lu Dai, Leon Schurgers, Paul G. Shiels, Peter Stenvinkel
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (10): 1251–1272.
DOI: https://doi.org/10.1042/CS20201452
Published: 26 May 2021
View article titled, A biomimetic natural sciences approach to understanding the mechanisms of ageing in burden of lifestyle diseases
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Articles

Arrb2 causes hepatic lipid metabolism disorder via AMPK pathway based on metabolomics in alcoholic fatty liver

Ying-Yin Sun, Dong-Qing Wu, Na-Na Yin, Lei Yang, Xin Chen, Hai-Di Li, Xiao-Feng Li, Cheng Huang, Xiao-Ming Meng, Hua Wang, Jun Li
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (10): 1213–1232.
DOI: https://doi.org/10.1042/CS20201363
Published: 20 May 2021
View article titled, Arrb2 causes hepatic lipid metabolism disorder via AMPK pathway based on metabolomics in alcoholic fatty liver
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Includes: Supplementary data
Articles

Emerging role of carbonic anhydrase inhibitors

Claudiu T. Supuran
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (10): 1233–1249.
DOI: https://doi.org/10.1042/CS20210040
Published: 20 May 2021
View article titled, Emerging role of carbonic anhydrase inhibitors
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Articles

Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction

Susana P. Pereira, Ludgero C. Tavares, Ana I. Duarte, Inês Baldeiras, Teresa Cunha-Oliveira, João D. Martins, Maria S. Santos, Alina Maloyan, António J. Moreno, Laura A. Cox, Cun Li, Peter W. Nathanielsz, Mark J. Nijland, Paulo J. Oliveira
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (9): 1103–1126.
DOI: https://doi.org/10.1042/CS20201339
Published: 11 May 2021
View article titled, Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction
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Includes: Supplementary data
Articles

IGF2 deficiency causes mitochondrial defects in skeletal muscle

Yiyi Zhu, Weiwei Gui, Bowen Tan, Ying Du, Jiaqiang Zhou, Fang Wu, Hong Li, Xihua Lin
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (7): 979–990.
DOI: https://doi.org/10.1042/CS20210128
Published: 16 April 2021
View article titled, IGF2 deficiency causes mitochondrial defects in skeletal muscle
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Includes: Supplementary data
Articles

The complex role of adipokines in obesity, inflammation, and autoimmunity

Erin B. Taylor
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (6): 731–752.
DOI: https://doi.org/10.1042/CS20200895
Published: 17 March 2021
View article titled, The complex role of adipokines in obesity, inflammation, and autoimmunity
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