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Articles

Essential metabolism required for T and B lymphocyte functions: an update

Vinicius Leonardo Sousa Diniz, Anuska Marcelino Alvares-Saraiva, Tamires Duarte Afonso Serdan, Laiane Cristina dos Santos-Oliveira, Vinicius Cruzat, Tiago Bertola Lobato, Richelieau Manoel, Amanda Lins Alecrim, Otavio Augusto Machado, Sandro M. Hirabara, Laureane Nunes Masi, Tania Cristina Pithon-Curi, Rui Curi, Renata Gorjão, Philip Newsholme
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (10): 807–821.
DOI: https://doi.org/10.1042/CS20220869
Published: 23 May 2023
View article titled, Essential metabolism required for T and B lymphocyte functions: an update
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Articles

Targeting TLR4/3 using chlorogenic acid ameliorates LPS+POLY I:C-induced acute respiratory distress syndrome via alleviating oxidative stress-mediated NLRP3/NF-κB axis

Siddhi Jain, Pritam Saha, Nayadi Parambil Syamprasad, Samir Rajan Panda, Bishal Rajdev, Arun Kumar Jannu, Pawan Sharma, Vegi Ganga Modi Naidu
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (10): 785–805.
DOI: https://doi.org/10.1042/CS20220625
Published: 23 May 2023
View article titled, Targeting TLR4/3 using chlorogenic acid ameliorates LPS+POLY I:C-induced acute respiratory distress syndrome via alleviating oxidative stress-mediated NLRP3/NF-κB axis
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Includes: Supplementary data
Articles

New insights into the pathophysiology and therapeutic targets of asthma and comorbid chronic rhinosinusitis with or without nasal polyposis

Ilja Striz, Kornel Golebski, Zuzana Strizova, Stelios Loukides, Petros Bakakos, Nicola A. Hanania, Milos Jesenak, Zuzana Diamant
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (9): 727–753.
DOI: https://doi.org/10.1042/CS20190281
Published: 18 May 2023
View article titled, New insights into the pathophysiology and therapeutic targets of asthma and comorbid chronic rhinosinusitis with or without nasal polyposis
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Articles

The role of hormones in sepsis: an integrated overview with a focus on mitochondrial and immune cell dysfunction

Miranda J. Melis, Muska Miller, Vera B.M. Peters, Mervyn Singer
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (9): 707–725.
DOI: https://doi.org/10.1042/CS20220709
Published: 05 May 2023
View article titled, The role of hormones in sepsis: an integrated overview with a focus on mitochondrial and immune cell dysfunction
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Articles

The leaky gut and the gut microbiome in sepsis – targets in research and treatment

Wiwat Chancharoenthana, Supitcha Kamolratanakul, Marcus J. Schultz, Asada Leelahavanichkul
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (8): 645–662.
DOI: https://doi.org/10.1042/CS20220777
Published: 21 April 2023
View article titled, The leaky gut and the gut microbiome in sepsis – targets in research and treatment
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Articles

Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension

Rahul Kumar, Michael H. Lee, Biruk Kassa, Dara C. Fonseca Balladares, Claudia Mickael, Linda Sanders, Adam Andruska, Maya Kumar, Edda Spiekerkoetter, Angela Bandeira, Kurt R. Stenmark, Rubin M. Tuder, Brian B Graham
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (8): 617–631.
DOI: https://doi.org/10.1042/CS20220642
Published: 21 April 2023
View article titled, Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension
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Includes: Supplementary data
Articles

Novel avenues to control blood pressure: targeting the renal lymphatic system

Andreia Zago Chignalia
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (8): 597–601.
DOI: https://doi.org/10.1042/CS20220775
Published: 19 April 2023
View article titled, Novel avenues to control blood pressure: targeting the renal lymphatic system
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Articles

How animal models can be utilized to find new biomarkers for cardiovascular diseases

Tatsuo Shimosawa
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (6): 527–535.
DOI: https://doi.org/10.1042/CS20220832
Published: 29 March 2023
View article titled, How animal models can be utilized to find new biomarkers for cardiovascular diseases
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Articles

By what molecular mechanisms do social determinants impact cardiometabolic risk?

Yvonne Baumer, Mario A. Pita, Andrew S. Baez, Lola R. Ortiz-Whittingham, Manuel A. Cintron, Rebecca R. Rose, Veronica C. Gray, Foster Osei Baah, Tiffany M. Powell-Wiley
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (6): 469–494.
DOI: https://doi.org/10.1042/CS20220304
Published: 24 March 2023
View article titled, By what molecular mechanisms do social determinants impact cardiometabolic risk?
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Includes: Supplementary data
Articles

Flavonoid derivative DMXAA attenuates cisplatin-induced acute kidney injury independent of STING signaling

Lingling Lu, Weihua Liu, Shumin Li, Mi Bai, Yu Zhou, Zhaohui Jiang, Zhanjun Jia, Songming Huang, Aihua Zhang, Wei Gong
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (6): 435–452.
DOI: https://doi.org/10.1042/CS20220728
Published: 21 March 2023
View article titled, Flavonoid derivative DMXAA attenuates cisplatin-induced acute kidney injury independent of STING signaling
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Includes: Supplementary data
Articles

Neurochemical effects of sepsis on the brain

Tatiana Barichello, Vijayasree V Giridharan, Carlos Henrique R Catalão, Cristiane Ritter, Felipe Dal-Pizzol
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (6): 401–414.
DOI: https://doi.org/10.1042/CS20220549
Published: 21 March 2023
View article titled, Neurochemical effects of sepsis on the brain
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Articles

TLR2 and 4 signaling pathways are altered in macrophages from V30M TTR mice with down-regulated expression of chemokines

João Moreira, Helena Martins, Margarida Saraiva, Maria João Saraiva
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (5): 355–366.
DOI: https://doi.org/10.1042/CS20220656
Published: 09 March 2023
View article titled, TLR2 and 4 signaling pathways are altered in macrophages from V30M TTR mice with down-regulated expression of chemokines
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Includes: Supplementary data
Articles

The long noncoding RNA Meg3 mediates TLR4-induced inflammation in experimental obstructive nephropathy

Wai Han Yiu, Sarah W.Y. Lok, Rui Xue, Jiaoyi Chen, Kar Neng Lai, Hui Yao Lan, Sydney C.W. Tang
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (5): 317–331.
DOI: https://doi.org/10.1042/CS20220537
Published: 01 March 2023
View article titled, The long noncoding RNA Meg3 mediates TLR4-induced inflammation in experimental obstructive nephropathy
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Includes: Supplementary data
Articles

The double sides of NLRP3 inflammasome activation in sepsis

Clara Vigneron, Bénédicte F. Py, Guillaume Monneret, Fabienne Venet
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (5): 333–351.
DOI: https://doi.org/10.1042/CS20220556
Published: 01 March 2023
View article titled, The double sides of NLRP3 inflammasome activation in sepsis
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Articles

The tendency of anemia of inflammation in periodontal diseases

Ye Han, Zhiqiang Luo, Zhao Guo Yue, Li Li Miao, Min Xv, Shu Chang, Yalin Zhan, Jianxia Hou
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (3): 251–264.
DOI: https://doi.org/10.1042/CS20220524
Published: 08 February 2023
View article titled, The tendency of anemia of inflammation in periodontal diseases
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Includes: Supplementary data
Articles

Iron and mitochondria in the susceptibility, pathogenesis and progression of COPD

Lynne Faherty, Sarah Kenny, Suzanne M. Cloonan
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (3): 219–237.
DOI: https://doi.org/10.1042/CS20210504
Published: 02 February 2023
View article titled, Iron and mitochondria in the susceptibility, pathogenesis and progression of COPD
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Articles

Increased β1-adrenergic receptor antibody confers a vulnerable substrate for atrial fibrillation via mediating Ca 2+ mishandling and atrial fibrosis in active immunization rabbit models

Huaxin Sun, Jie Song, Kai Li, Yao Li, Luxiang Shang, Qina Zhou, Yanmei Lu, Yazhen Zong, Xiuyuan He, Muzappar Kari, Hang Yang, Xianhui Zhou, Ling Zhang, Baopeng Tang
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (2): 195–217.
DOI: https://doi.org/10.1042/CS20220654
Published: 27 January 2023
View article titled, Increased β1-adrenergic receptor antibody confers a vulnerable substrate for atrial fibrillation via mediating Ca 2+ mishandling and atrial fibrosis in active immunization rabbit models
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Includes: Supplementary data
Articles

Cigarette smoke induces mitochondrial DNA damage and activates cGAS-STING pathway: application to a biomarker for atherosclerosis

Keitaro Ueda, Chiemi Sakai, Takafumi Ishida, Kosuke Morita, Yusuke Kobayashi, Yasunori Horikoshi, Akiko Baba, Yuma Okazaki, Masao Yoshizumi, Satoshi Tashiro, Mari Ishida
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (2): 163–180.
DOI: https://doi.org/10.1042/CS20220525
Published: 24 January 2023
View article titled, Cigarette smoke induces mitochondrial DNA damage and activates cGAS-STING pathway: application to a biomarker for atherosclerosis
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Includes: Supplementary data
Articles

PARK7 is induced to protect against endotoxic acute kidney injury by suppressing NF-κB

Honglin Li, Zhiwen Liu, Ying Wang, Hui Wang, Juan Cai, Chengyuan Tang, Zheng Dong
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (24): 1877–1891.
DOI: https://doi.org/10.1042/CS20220493
Published: 22 December 2022
View article titled, PARK7 is induced to protect against endotoxic acute kidney injury by suppressing NF-κB
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Articles

Dysregulated haemostasis in thrombo-inflammatory disease

Paula A. Klavina, Gemma Leon, Annie M. Curtis, Roger J.S. Preston
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (24): 1809–1829.
DOI: https://doi.org/10.1042/CS20220208
Published: 16 December 2022
View article titled, Dysregulated haemostasis in thrombo-inflammatory disease
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Articles

Genetically inducing renal lymphangiogenesis attenuates hypertension in mice

Bethany L. Goodlett, Dakshnapriya Balasubbramanian, Shobana Navaneethabalakrishnan, Sydney E. Love, Emily M. Luera, Sunitha Konatham, Valorie L. Chiasson, Sophie Wedgeworth, Joseph M. Rutkowski, Brett M. Mitchell
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (23): 1759–1772.
DOI: https://doi.org/10.1042/CS20220547
Published: 02 December 2022
View article titled, Genetically inducing renal lymphangiogenesis attenuates hypertension in mice
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Includes: Supplementary data
Articles

Depot-specific adipose tissue modulation by SGLT2 inhibitors and GLP1 agonists mediates their cardioprotective effects in metabolic disease

Nour-Mounira Z. Bakkar, Ibrahim AlZaim, Ahmed F. El-Yazbi
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (22): 1631–1651.
DOI: https://doi.org/10.1042/CS20220404
Published: 16 November 2022
View article titled, Depot-specific adipose tissue modulation by SGLT2 inhibitors and GLP1 agonists mediates their cardioprotective effects in metabolic disease
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Articles

Therapeutic use of calpeptin in COVID-19 infection

In Collection
Coronavirus
Jameel Inal, Ainura Paizuldaeva, Esmeralda Terziu
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (20): 1439–1447.
DOI: https://doi.org/10.1042/CS20220638
Published: 21 October 2022
View article titled, Therapeutic use of calpeptin in COVID-19 infection
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Articles

Severe psychiatric disorders and general medical comorbidities: inflammation-related mechanisms and therapeutic opportunities

Antonio L. Teixeira, Lais B. Martins, Michael Berk, Moisés E. Bauer
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (17): 1257–1280.
DOI: https://doi.org/10.1042/CS20211106
Published: 05 September 2022
View article titled, Severe psychiatric disorders and general medical comorbidities: inflammation-related mechanisms and therapeutic opportunities
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Articles

Maternal immune activation in rats induces dysfunction of placental leucine transport and alters fetal brain growth

Hager M. Kowash, Harry G. Potter, Rebecca M. Woods, Nick Ashton, Reinmar Hager, Joanna C. Neill, Jocelyn D. Glazier
Journal: Clinical Science
Clin Sci (Lond) (2022) 1117–1137.
DOI: https://doi.org/10.1042/CS20220245
Published: 05 August 2022
View article titled, Maternal immune activation in rats induces dysfunction of placental leucine transport and alters fetal brain growth
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Includes: Supplementary data
Articles

Modulating hepatic macrophages with annexin A1 in non-alcoholic steatohepatitis

Federico F. De Ponti, Charlotte L. Scott
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (15): 1111–1115.
DOI: https://doi.org/10.1042/CS20220258
Published: 01 August 2022
View article titled, Modulating hepatic macrophages with annexin A1 in non-alcoholic steatohepatitis
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Articles

Casting a wide NET: an update on uncontrolled NETosis in response to COVID-19 infection

Erin B. Taylor
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (13): 1047–1052.
DOI: https://doi.org/10.1042/CS20220039
Published: 06 July 2022
View article titled, Casting a wide NET: an update on uncontrolled NETosis in response to COVID-19 infection
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Articles

L-Glutamine alleviates osteoarthritis by regulating lncRNA-NKILA expression through the TGF-β1/SMAD2/3 signalling pathway

Xiao Ma, Dechao Cai, Yakun Zhu, Yao Zhao, Xianbo Shang, Chen Wang, Haotian Zhang, Ashuai Bian, Haoran Yu, Wendan Cheng
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (13): 1053–1069.
DOI: https://doi.org/10.1042/CS20220082
Published: 06 July 2022
View article titled, L-Glutamine alleviates osteoarthritis by regulating lncRNA-NKILA expression through the TGF-β1/SMAD2/3 signalling pathway
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Articles

Molecular and cellular regulation of psoriatic inflammation

Tom Macleod, Charles Bridgewood, Isabel Hyde, Megan Heague, Philip Helliwell, Martin Stacey, Miriam Wittmann
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (12): 935–952.
DOI: https://doi.org/10.1042/CS20210916
Published: 22 June 2022
View article titled, Molecular and cellular regulation of psoriatic inflammation
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Articles

Hypertension induces gonadal macrophage imbalance, inflammation, lymphangiogenesis, and dysfunction

Shobana Navaneethabalakrishnan, Brooke K. Wilcox, Bethany L. Goodlett, Malea M. Murphy, Brett M. Mitchell
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (11): 879–894.
DOI: https://doi.org/10.1042/CS20220117
Published: 06 June 2022
View article titled, Hypertension induces gonadal macrophage imbalance, inflammation, lymphangiogenesis, and dysfunction
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Includes: Supplementary data
Articles

Novel insights in endocrine and metabolic pathways in sepsis and gaps for future research

Arno Téblick, Jan Gunst, Lies Langouche, Greet Van den Berghe
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (11): 861–878.
DOI: https://doi.org/10.1042/CS20211003
Published: 01 June 2022
View article titled, Novel insights in endocrine and metabolic pathways in sepsis and gaps for future research
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Articles

Pathogenesis of pneumonia and acute lung injury

Matthew E. Long, Rama K. Mallampalli, Jeffrey C. Horowitz
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (10): 747–769.
DOI: https://doi.org/10.1042/CS20210879
Published: 27 May 2022
View article titled, Pathogenesis of pneumonia and acute lung injury
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Articles

Mechanisms underlying immune-related adverse events during checkpoint immunotherapy

Xiao Zhou, Xiang Chen, Leng Han, Hong Liu
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (10): 771–785.
DOI: https://doi.org/10.1042/CS20210042
Published: 27 May 2022
View article titled, Mechanisms underlying immune-related adverse events during checkpoint immunotherapy
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Articles

Clinical perspectives on vagus nerve stimulation: present and future

Eibhlin Goggins, Shuhei Mitani, Shinji Tanaka
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (9): 695–709.
DOI: https://doi.org/10.1042/CS20210507
Published: 10 May 2022
View article titled, Clinical perspectives on vagus nerve stimulation: present and future
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Articles

Annexin A1 treatment prevents the evolution to fibrosis of experimental nonalcoholic steatohepatitis

Laila Lavanya Gadipudi, Naresh Naik Ramavath, Alessia Provera, Chris Reutelingsperger, Emanuele Albano, Mauro Perretti, Salvatore Sutti
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (9): 643–656.
DOI: https://doi.org/10.1042/CS20211122
Published: 04 May 2022
View article titled, Annexin A1 treatment prevents the evolution to fibrosis of experimental nonalcoholic steatohepatitis
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Includes: Supplementary data
Articles

Ebselen abolishes vascular dysfunction in influenza A virus-induced exacerbations of cigarette smoke-induced lung inflammation in mice

Kurt Brassington, Stanley M.H. Chan, Simone N. De Luca, Aleksandar Dobric, Suleman A. Almerdasi, Kevin Mou, Huei Jiunn Seow, Osezua Oseghale, Steven Bozinovski, Stavros Selemidis, Ross Vlahos
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (8): 537–555.
DOI: https://doi.org/10.1042/CS20211090
Published: 21 April 2022
View article titled, Ebselen abolishes vascular dysfunction in influenza A virus-induced exacerbations of cigarette smoke-induced lung inflammation in mice
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Articles

Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease

Eva Maria Pastor Arroyo, Nima Yassini, Elif Sakiri, Giancarlo Russo, Soline Bourgeois, Nilufar Mohebbi, Kerstin Amann, Nicole Joller, Carsten A. Wagner, Pedro Henrique Imenez Silva
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (8): 557–577.
DOI: https://doi.org/10.1042/CS20220095
Published: 21 April 2022
View article titled, Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease
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Includes: Supplementary data
Articles

Molecular mechanisms of tumour budding and its association with microenvironment in colorectal cancer

Phimmada Hatthakarnkul, Jean A. Quinn, Aula Ammar, Gerard Lynch, Hester Van Wyk, Donald C. McMillan, Chanitra Thuwajit, Joanne Edwards
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (8): 521–535.
DOI: https://doi.org/10.1042/CS20210886
Published: 21 April 2022
View article titled, Molecular mechanisms of tumour budding and its association with microenvironment in colorectal cancer
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Articles

Inhibition of Notch activity suppresses hyperglycemia-augmented polarization of macrophages to the M1 phenotype and alleviates acute pancreatitis

Ning Hu, Xiaoyi Zhang, Xuanzhe Zhang, Yongjun Guan, Ruyuan He, Enfu Xue, Xiaoyi Zhang, Wenhong Deng, Jia Yu, Weixing Wang, Qiao Shi
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (7): 455–471.
DOI: https://doi.org/10.1042/CS20211031
Published: 06 April 2022
View article titled, Inhibition of Notch activity suppresses hyperglycemia-augmented polarization of macrophages to the M1 phenotype and alleviates acute pancreatitis
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Includes: Supplementary data
Articles

Metabolism in atherosclerotic plaques: immunoregulatory mechanisms in the arterial wall

Maria J. Forteza, Daniel F.J. Ketelhuth
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (6): 435–454.
DOI: https://doi.org/10.1042/CS20201293
Published: 29 March 2022
View article titled, Metabolism in atherosclerotic plaques: immunoregulatory mechanisms in the arterial wall
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Articles

Chronic obstructive pulmonary disease and atherosclerosis: common mechanisms and novel therapeutics

Kurt Brassington, Stavros Selemidis, Steven Bozinovski, Ross Vlahos
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (6): 405–423.
DOI: https://doi.org/10.1042/CS20210835
Published: 23 March 2022
View article titled, Chronic obstructive pulmonary disease and atherosclerosis: common mechanisms and novel therapeutics
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Articles

Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway

Liping Liang, Le Liu, Wanyan Zhou, Chenghai Yang, Genghui Mai, Haolin Li, Ye Chen
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (4): 291–307.
DOI: https://doi.org/10.1042/CS20210778
Published: 23 February 2022
View article titled, Gut microbiota-derived butyrate regulates gut mucus barrier repair by activating the macrophage/WNT/ERK signaling pathway
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Includes: Supplementary data
Articles

The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer

Richard Cunningham, Carsten Gram Hansen
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (3): 197–222.
DOI: https://doi.org/10.1042/CS20201474
Published: 04 February 2022
View article titled, The Hippo pathway in cancer: YAP/TAZ and TEAD as therapeutic targets in cancer
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Articles

Inhalation of dimethyl fumarate-encapsulated solid lipid nanoparticles attenuate clinical signs of experimental autoimmune encephalomyelitis and pulmonary inflammatory dysfunction in mice

Bárbara Fernandes Pinto, Lorena Natasha Brito Ribeiro, Gisela Bevilacqua Rolfsen Ferreira da Silva, Camila Simões Freitas, Lucas Kraemer, Fabrício Marcus Silva Oliveira, Marianna Carvalho Clímaco, Flávio Afonso Gonçalves Mourão, Gabryella Soares Pinheiro dos Santos, Samantha Ribeiro Béla, Isabella Luísa da Silva Gurgel, Fábio de Lima Leite, Anselmo Gomes de Oliveira, Maura Regina Silva da Páscoa Vilela, Onésia Cristina Oliveira-Lima, Frederico Marianetti Soriani, Ricardo Toshio Fujiwara, Alexander Birbrair, Remo Castro Russo, Juliana Carvalho-Tavares
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (1): 81–101.
DOI: https://doi.org/10.1042/CS20210792
Published: 07 January 2022
View article titled, Inhalation of dimethyl fumarate-encapsulated solid lipid nanoparticles attenuate clinical signs of experimental autoimmune encephalomyelitis and pulmonary inflammatory dysfunction in mice
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Articles

AIM2 inflammasome contributes to aldosterone-induced renal injury via endoplasmic reticulum stress

Yong Wu, Huan Yang, Sujuan Xu, Ming Cheng, Jie Gu, Weichen Zhang, Shaojun Liu, Minmin Zhang
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (1): 103–120.
DOI: https://doi.org/10.1042/CS20211075
Published: 07 January 2022
View article titled, AIM2 inflammasome contributes to aldosterone-induced renal injury via endoplasmic reticulum stress
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Includes: Supplementary data
Articles

Mechanisms of immune aging in HIV

Manon Chauvin, Delphine Sauce
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (1): 61–80.
DOI: https://doi.org/10.1042/CS20210344
Published: 05 January 2022
View article titled, Mechanisms of immune aging in HIV
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Articles

WNT1-inducible signaling pathway protein 1 regulates kidney inflammation through the NF-κB pathway

Bo Wang, Chenguang Ding, Xiaoming Ding, Greg Tesch, Jin Zheng, PuYun Tian, Yang Li, Sharon Ricardo, Hsin-Hui Shen, Wujun Xue
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (1): 29–44.
DOI: https://doi.org/10.1042/CS20210663
Published: 05 January 2022
View article titled, WNT1-inducible signaling pathway protein 1 regulates kidney inflammation through the NF-κB pathway
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Includes: Supplementary data
Articles

Erythrocytes increase endogenous sphingosine 1-phosphate levels as an adaptive response to SARS-CoV-2 infection

In Collection
Coronavirus
Martin Sebastian Winkler, Ralf Alexander Claus, Mareike Schilder, Stefan Pöhlmann, Sina M. Coldewey, Julian Grundmann, Torben Fricke, Onnen Moerer, Konrad Meissner, Michael Bauer, Heike Hofmann-Winkler, Markus H. Gräler
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (24): 2781–2791.
DOI: https://doi.org/10.1042/CS20210666
Published: 22 December 2021
View article titled, Erythrocytes increase endogenous sphingosine 1-phosphate levels as an adaptive response to SARS-CoV-2 infection
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Articles

Asthma and obesity: endotoxin another insult to add to injury?

Nikita Lad, Alice M. Murphy, Cristina Parenti, Carl P. Nelson, Neil C. Williams, Graham R. Sharpe, Philip G. McTernan
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (24): 2729–2748.
DOI: https://doi.org/10.1042/CS20210790
Published: 17 December 2021
View article titled, Asthma and obesity: endotoxin another insult to add to injury?
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Articles

Helicobacter pylori -induced REDD1 modulates Th17 cell responses that contribute to gastritis

Zong-Bao Yan, Jin-Yu Zhang, Yi-Pin Lv, Wen-Qing Tian, Zhi-Guo Shan, Fang-Yuan Mao, Yu-Gang Liu, Wan-Yan Chen, Pan Wang, Yun Yang, Ping Cheng, Liu-Sheng Peng, Ya-Ling Liao, Geng-Yu Yue, Xiao-Lin Xu, Yong-Liang Zhao, Mu-Han Lü, Yuan Zhuang
Journal: Clinical Science
Clin Sci (Lond) (2021) 135 (22): 2541–2558.
DOI: https://doi.org/10.1042/CS20210753
Published: 26 November 2021
View article titled, Helicobacter pylori -induced REDD1 modulates Th17 cell responses that contribute to gastritis
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Includes: Supplementary data