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Cardiovascular System & Vascular Biology
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Articles

Akt2 deficiency alleviates oxidative stress in the heart and liver via up-regulating SIRT6 during high-fat diet-induced obesity

Weixian Kong, Yue Peng, Caoyu Ji, Zekun Liu, Shuya Gao, Yuexin Zhang, Jiawen Chen, Xie Li, Mengmeng Bao, Yubin Zhang, Qizhou Jiang, Fuqun Wang, Zhe Li, Xiaohong Bian, Junmei Ye
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (10): 823–841.
DOI: https://doi.org/10.1042/CS20230433
Published: 31 May 2023
View article titled, Akt2 deficiency alleviates oxidative stress in the heart and liver via up-regulating SIRT6 during high-fat diet-induced obesity
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Includes: Supplementary data
Articles

Revisiting blood pressure and body fluid status

Kento Kitada, Akira Nishiyama
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (9): 755–767.
DOI: https://doi.org/10.1042/CS20220500
Published: 18 May 2023
View article titled, Revisiting blood pressure and body fluid status
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Articles

Don’t sweat the small stuff: skin mechanisms of sodium homeostasis and associations with long-term blood pressure

Joshua S. Speed, David M. Pollock, John S. Clemmer
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (9): 769–772.
DOI: https://doi.org/10.1042/CS20230163
Published: 18 May 2023
View article titled, Don’t sweat the small stuff: skin mechanisms of sodium homeostasis and associations with long-term blood pressure
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Articles

Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension

Rahul Kumar, Michael H. Lee, Biruk Kassa, Dara C. Fonseca Balladares, Claudia Mickael, Linda Sanders, Adam Andruska, Maya Kumar, Edda Spiekerkoetter, Angela Bandeira, Kurt R. Stenmark, Rubin M. Tuder, Brian B Graham
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (8): 617–631.
DOI: https://doi.org/10.1042/CS20220642
Published: 21 April 2023
View article titled, Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension
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Includes: Supplementary data
Articles

Novel avenues to control blood pressure: targeting the renal lymphatic system

Andreia Zago Chignalia
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (8): 597–601.
DOI: https://doi.org/10.1042/CS20220775
Published: 19 April 2023
View article titled, Novel avenues to control blood pressure: targeting the renal lymphatic system
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Articles

Beneficial effects of brief early life angiotensin-converting enzyme inhibition wane with time in sheep with solitary functioning kidney

Zoe McArdle, Reetu R. Singh, Helle Bielefeldt-Ohmann, Karen M. Moritz, Kate M. Denton, Michiel F. Schreuder
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (8): 603–615.
DOI: https://doi.org/10.1042/CS20220811
Published: 19 April 2023
View article titled, Beneficial effects of brief early life angiotensin-converting enzyme inhibition wane with time in sheep with solitary functioning kidney
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Articles

Cardiovascular research at the Heart of Clinical Science

Michael J. Ryan
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (7): 537–542.
DOI: https://doi.org/10.1042/CS20220497
Published: 13 April 2023
View article titled, Cardiovascular research at the Heart of Clinical Science
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Articles

TNF/iNOS/NO pathway mediates host susceptibility to endothelial-dependent circulatory failure and death induced by betacoronavirus infection

Ildernandes Vieira-Alves, Antonielle Rodrigues Pereira Alves, Natália Muradas Valério Souza, Tales Leonardo de Melo, Leda Maria de Castro Coimbra Campos, Larisse de Souza Barbosa Lacerda, Celso Martins Queiroz-Junior, Ana Cláudia dos Santos Pereira Andrade, Luciola Silva Barcelos, Mauro Martins Teixeira, Vivian Vasconcelos Costa, Steyner F. Cortes, Virginia S. Lemos
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (7): 543–559.
DOI: https://doi.org/10.1042/CS20220663
Published: 13 April 2023
View article titled, TNF/iNOS/NO pathway mediates host susceptibility to endothelial-dependent circulatory failure and death induced by betacoronavirus infection
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Includes: Supplementary data
Articles

How animal models can be utilized to find new biomarkers for cardiovascular diseases

Tatsuo Shimosawa
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (6): 527–535.
DOI: https://doi.org/10.1042/CS20220832
Published: 29 March 2023
View article titled, How animal models can be utilized to find new biomarkers for cardiovascular diseases
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Articles

Cardioprotective and anti-inflammatory effects of Caveolin 1 in experimental diabetic cardiomyopathy

Wenyan Gong, Qibin Jiao, Jinghua Yuan, Hui Luo, Yingying Liu, Yuanyuan Zhang, Zhen Chen, Xiaoling Xu, Lin Bai, Xingwei Zhang
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (6): 511–525.
DOI: https://doi.org/10.1042/CS20220874
Published: 24 March 2023
View article titled, Cardioprotective and anti-inflammatory effects of Caveolin 1 in experimental diabetic cardiomyopathy
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Articles

By what molecular mechanisms do social determinants impact cardiometabolic risk?

Yvonne Baumer, Mario A. Pita, Andrew S. Baez, Lola R. Ortiz-Whittingham, Manuel A. Cintron, Rebecca R. Rose, Veronica C. Gray, Foster Osei Baah, Tiffany M. Powell-Wiley
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (6): 469–494.
DOI: https://doi.org/10.1042/CS20220304
Published: 24 March 2023
View article titled, By what molecular mechanisms do social determinants impact cardiometabolic risk?
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Includes: Supplementary data
Articles

Skin-specific mechanisms of body fluid regulation in hypertension

Jun Yu Chen, Khai Syuen Chew, Sheon Mary, Philipp Boder, Domenico Bagordo, Gian Paolo Rossi, Rhian M. Touyz, Christian Delles, Giacomo Rossitto
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (3): 239–250.
DOI: https://doi.org/10.1042/CS20220609
Published: 07 February 2023
View article titled, Skin-specific mechanisms of body fluid regulation in hypertension
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Includes: Supplementary data
Articles

Increased β1-adrenergic receptor antibody confers a vulnerable substrate for atrial fibrillation via mediating Ca 2+ mishandling and atrial fibrosis in active immunization rabbit models

Huaxin Sun, Jie Song, Kai Li, Yao Li, Luxiang Shang, Qina Zhou, Yanmei Lu, Yazhen Zong, Xiuyuan He, Muzappar Kari, Hang Yang, Xianhui Zhou, Ling Zhang, Baopeng Tang
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (2): 195–217.
DOI: https://doi.org/10.1042/CS20220654
Published: 27 January 2023
View article titled, Increased β1-adrenergic receptor antibody confers a vulnerable substrate for atrial fibrillation via mediating Ca 2+ mishandling and atrial fibrosis in active immunization rabbit models
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Includes: Supplementary data
Articles

Cigarette smoke induces mitochondrial DNA damage and activates cGAS-STING pathway: application to a biomarker for atherosclerosis

Keitaro Ueda, Chiemi Sakai, Takafumi Ishida, Kosuke Morita, Yusuke Kobayashi, Yasunori Horikoshi, Akiko Baba, Yuma Okazaki, Masao Yoshizumi, Satoshi Tashiro, Mari Ishida
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (2): 163–180.
DOI: https://doi.org/10.1042/CS20220525
Published: 24 January 2023
View article titled, Cigarette smoke induces mitochondrial DNA damage and activates cGAS-STING pathway: application to a biomarker for atherosclerosis
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Includes: Supplementary data
Articles

Central role for BRAF in cardiac hypertrophy: rethinking the pathological–physiological divide

Raffaele Altara, George W. Booz
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (2): 143–148.
DOI: https://doi.org/10.1042/CS20220776
Published: 18 January 2023
View article titled, Central role for BRAF in cardiac hypertrophy: rethinking the pathological–physiological divide
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Articles

Sexual dimorphism in acute myocardial infarction-induced acute kidney injury: cardiorenal deteriorating effects of ovariectomy in premenopausal female mice

Nada J. Habeichi, Rana Ghali, Ali Mroueh, Abdullah Kaplan, Cynthia Tannous, Abdo Jurjus, Ghadir Amin, Mathias Mericskay, George W. Booz, Ahmed El-Yazbi, Fouad A. Zouein
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (1): 47–63.
DOI: https://doi.org/10.1042/CS20220513
Published: 05 January 2023
View article titled, Sexual dimorphism in acute myocardial infarction-induced acute kidney injury: cardiorenal deteriorating effects of ovariectomy in premenopausal female mice
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Includes: Supplementary data
Articles

Set7 methyltransferase roles in myocardial protection from chronic stressors

James T. Pearson
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (1): 105–108.
DOI: https://doi.org/10.1042/CS20220773
Published: 05 January 2023
View article titled, Set7 methyltransferase roles in myocardial protection from chronic stressors
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Articles

Inhibition of monoamine oxidase B reduces atherosclerosis and fatty liver in mice

Shu-Huei Wang, Feng-Chiao Tsai, Heng-Huei Lin, Tse-Ya Yu, Chun-Heng Kuo, Hung-Yuan Li, Mao-Shin Lin
Journal: Clinical Science
Clin Sci (Lond) (2023) 137 (1): 17–30.
DOI: https://doi.org/10.1042/CS20220477
Published: 03 January 2023
View article titled, Inhibition of monoamine oxidase B reduces atherosclerosis and fatty liver in mice
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Articles

Novel preventive effect of isorhamnetin on electrical and structural remodeling in atrial fibrillation

Kazuhiro Aonuma, DongZhu Xu, Nobuyuki Murakoshi, Kazuko Tajiri, Yuta Okabe, Zixun Yuan, Siqi Li, Yoshiko Murakata, Kenichi Tominaga, Akihiko Nogami, Kazutaka Aonuma, Masaki Ieda, Hiroko Isoda
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (24): 1831–1849.
DOI: https://doi.org/10.1042/CS20220319
Published: 21 December 2022
View article titled, Novel preventive effect of isorhamnetin on electrical and structural remodeling in atrial fibrillation
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Articles

Dysregulated haemostasis in thrombo-inflammatory disease

Paula A. Klavina, Gemma Leon, Annie M. Curtis, Roger J.S. Preston
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (24): 1809–1829.
DOI: https://doi.org/10.1042/CS20220208
Published: 16 December 2022
View article titled, Dysregulated haemostasis in thrombo-inflammatory disease
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Articles

Genetically inducing renal lymphangiogenesis attenuates hypertension in mice

Bethany L. Goodlett, Dakshnapriya Balasubbramanian, Shobana Navaneethabalakrishnan, Sydney E. Love, Emily M. Luera, Sunitha Konatham, Valorie L. Chiasson, Sophie Wedgeworth, Joseph M. Rutkowski, Brett M. Mitchell
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (23): 1759–1772.
DOI: https://doi.org/10.1042/CS20220547
Published: 02 December 2022
View article titled, Genetically inducing renal lymphangiogenesis attenuates hypertension in mice
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Includes: Supplementary data
Articles

Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery

Lauren T. May, Belinda A. Bartolo, David G. Harrison, Tomasz Guzik, Grant R. Drummond, Gemma A. Figtree, Rebecca H. Ritchie, Kerry-Anne Rye, Judy B. de Haan
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (23): 1731–1758.
DOI: https://doi.org/10.1042/CS20210862
Published: 02 December 2022
View article titled, Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery
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Articles

Cardiomyocyte BRAF is a key signalling intermediate in cardiac hypertrophy in mice

Hajed O. Alharbi, Michelle A. Hardyman, Joshua J. Cull, Thomais Markou, Susanna T.E. Cooper, Peter E. Glennon, Stephen J. Fuller, Peter H. Sugden, Angela Clerk
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (22): 1661–1681.
DOI: https://doi.org/10.1042/CS20220607
Published: 21 November 2022
View article titled, Cardiomyocyte BRAF is a key signalling intermediate in cardiac hypertrophy in mice
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Includes: Supplementary data
Articles

Quantifying muscle blood flow: a transformative breakthrough in the science of human exercise physiology

Thomas P. Olson, Joshua R. Smith, Timothy B. Curry
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (22): 1653–1656.
DOI: https://doi.org/10.1042/CS20220101
Published: 18 November 2022
View article titled, Quantifying muscle blood flow: a transformative breakthrough in the science of human exercise physiology
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Articles

Depot-specific adipose tissue modulation by SGLT2 inhibitors and GLP1 agonists mediates their cardioprotective effects in metabolic disease

Nour-Mounira Z. Bakkar, Ibrahim AlZaim, Ahmed F. El-Yazbi
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (22): 1631–1651.
DOI: https://doi.org/10.1042/CS20220404
Published: 16 November 2022
View article titled, Depot-specific adipose tissue modulation by SGLT2 inhibitors and GLP1 agonists mediates their cardioprotective effects in metabolic disease
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Articles

Vascular dysfunction in COVID-19 patients: update on SARS-CoV-2 infection of endothelial cells and the role of long non-coding RNAs

In Collection
Coronavirus
Jaroslav Pelisek, Benedikt Reutersberg, Urs F Greber, Alexander Zimmermann
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (21): 1571–1590.
DOI: https://doi.org/10.1042/CS20220235
Published: 11 November 2022
View article titled, Vascular dysfunction in COVID-19 patients: update on SARS-CoV-2 infection of endothelial cells and the role of long non-coding RNAs
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Articles

Set7 deletion attenuates isoproterenol-induced cardiac fibrosis and delays cardiac dysfunction

Guilherme Lunardon, Tábatha de Oliveira Silva, Caroline A. Lino, Yao Wei Lu, Juliane B. Miranda, Paula F. Asprino, Amanda de Almeida Silva, Gabrielle T. Nepomuceno, Maria Cláudia Costa Irigoyen, Marcela S. Carneiro-Ramos, Ana Paula C. Takano, Herculano da Silva Martinho, Maria Luiza M. Barreto-Chaves, Da-Zhi Wang, Gabriela P. Diniz
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (21): 1537–1554.
DOI: https://doi.org/10.1042/CS20220466
Published: 10 November 2022
View article titled, Set7 deletion attenuates isoproterenol-induced cardiac fibrosis and delays cardiac dysfunction
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Includes: Supplementary data
Articles

Magnetic resonance imaging reveals microemboli-mediated pathological changes in brain microstructure in diabetic rats: relevance to vascular cognitive impairment/dementia

Raghavendar Chandran, Lianying He, Xingju Nie, Joshua Voltin, Sarah Jamil, Caren Doueiry, Maria Fatima Falangola, Adviye Ergul, Weiguo Li
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (21): 1555–1570.
DOI: https://doi.org/10.1042/CS20220465
Published: 10 November 2022
View article titled, Magnetic resonance imaging reveals microemboli-mediated pathological changes in brain microstructure in diabetic rats: relevance to vascular cognitive impairment/dementia
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Includes: Supplementary data
Articles

CGP42112: the full AT 2 receptor agonist and its role in the renin–angiotensin–aldosterone system: no longer misunderstood

Yazmin M. Restrepo, Natalia M. Noto, Robert C. Speth
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (21): 1513–1533.
DOI: https://doi.org/10.1042/CS20220261
Published: 03 November 2022
View article titled, CGP42112: the full AT 2 receptor agonist and its role in the renin–angiotensin–aldosterone system: no longer misunderstood
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Includes: Supplementary data
Articles

Circulating cell-free micro-RNA as biomarkers: from myocardial infarction to hypertension

Jessica L. Faulkner, Jennifer C. Sullivan
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (18): 1341–1346.
DOI: https://doi.org/10.1042/CS20220056
Published: 21 September 2022
View article titled, Circulating cell-free micro-RNA as biomarkers: from myocardial infarction to hypertension
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Articles

Hypertension and renal disease programming: focus on the early postnatal period

Maria Florencia Albertoni Borghese, Lucas Humberto Oronel, Maria Del Carmen Ortiz, Mónica Patricia Majowicz
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (17): 1303–1339.
DOI: https://doi.org/10.1042/CS20220293
Published: 08 September 2022
View article titled, Hypertension and renal disease programming: focus on the early postnatal period
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Articles

Multicellular regulation of miR-196a-5p and miR-425-5 from adipose stem cell-derived exosomes and cardiac repair

Nathalia C. de Almeida Oliveira, Elida A. Neri, Caio M. Silva, Iuri C. Valadão, Miriam H. Fonseca-Alaniz, Camila Zogbi, Débora Levy, Sergio P. Bydlowski, Jose Eduardo Krieger
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (17): 1281–1301.
DOI: https://doi.org/10.1042/CS20220216
Published: 05 September 2022
View article titled, Multicellular regulation of miR-196a-5p and miR-425-5 from adipose stem cell-derived exosomes and cardiac repair
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Includes: Supplementary data
Articles

The complex genetic basis of fibromuscular dysplasia, a systemic arteriopathy associated with multiple forms of cardiovascular disease

Adrien Georges, Nabila Bouatia-Naji
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (16): 1241–1255.
DOI: https://doi.org/10.1042/CS20210990
Published: 31 August 2022
View article titled, The complex genetic basis of fibromuscular dysplasia, a systemic arteriopathy associated with multiple forms of cardiovascular disease
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Articles

The negative regulation of gene expression by microRNAs as key driver of inducers and repressors of cardiomyocyte differentiation

Eleonora Cianflone, Mariangela Scalise, Fabiola Marino, Luca Salerno, Nadia Salerno, Konrad Urbanek, Daniele Torella
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (16): 1179–1203.
DOI: https://doi.org/10.1042/CS20220391
Published: 18 August 2022
View article titled, The negative regulation of gene expression by microRNAs as key driver of inducers and repressors of cardiomyocyte differentiation
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Articles

The multifaceted actions of the lncRNA H19 in cardiovascular biology and diseases

Denise Busscher, Reinier A. Boon, Rio P. Juni
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (15): 1157–1178.
DOI: https://doi.org/10.1042/CS20210994
Published: 10 August 2022
View article titled, The multifaceted actions of the lncRNA H19 in cardiovascular biology and diseases
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Articles

G-protein-coupled receptor kinase 4 causes renal angiotensin II type 2 receptor dysfunction by increasing its phosphorylation

Fuwei Zhang, Lifu Lei, Juan Huang, Weiwei Wang, Qian Su, Hongjia Yan, Caiyu Chen, Shuo Zheng, Hongmei Ren, Zhuxin Li, Pedro A. Jose, Yijie Hu, Liangyi Si, Chunyu Zeng, Jian Yang
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (12): 989–1003.
DOI: https://doi.org/10.1042/CS20220236
Published: 29 June 2022
View article titled, G-protein-coupled receptor kinase 4 causes renal angiotensin II type 2 receptor dysfunction by increasing its phosphorylation
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Includes: Supplementary data
Articles

The non-steroidal mineralocorticoid receptor antagonist finerenone is a novel therapeutic option for patients with Type 2 diabetes and chronic kidney disease

Jonatan Barrera-Chimal, Casimiro Gerarduzzi, Patrick Rossignol, Frédéric Jaisser
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (12): 1005–1017.
DOI: https://doi.org/10.1042/CS20220212
Published: 29 June 2022
View article titled, The non-steroidal mineralocorticoid receptor antagonist finerenone is a novel therapeutic option for patients with Type 2 diabetes and chronic kidney disease
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Articles

Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction

Anna K. Whitehead, Nicholas D. Fried, Zhen Li, Kandasamy Neelamegam, Charlotte S. Pearson, Kyle B. LaPenna, Thomas E. Sharp, David J. Lefer, Eric Lazartigues, Jason D. Gardner, Xinping Yue
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (12): 973–987.
DOI: https://doi.org/10.1042/CS20220083
Published: 22 June 2022
View article titled, Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction
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Includes: Supplementary data
Articles

Defining the molecular underpinnings controlling cardiomyocyte proliferation

Donya Mahiny-Shahmohammady, Ludger Hauck, Filio Billia
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (12): 911–934.
DOI: https://doi.org/10.1042/CS20211180
Published: 20 June 2022
View article titled, Defining the molecular underpinnings controlling cardiomyocyte proliferation
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Articles

Hypertension induces gonadal macrophage imbalance, inflammation, lymphangiogenesis, and dysfunction

Shobana Navaneethabalakrishnan, Brooke K. Wilcox, Bethany L. Goodlett, Malea M. Murphy, Brett M. Mitchell
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (11): 879–894.
DOI: https://doi.org/10.1042/CS20220117
Published: 06 June 2022
View article titled, Hypertension induces gonadal macrophage imbalance, inflammation, lymphangiogenesis, and dysfunction
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Includes: Supplementary data
Articles

Persistent vascular congestion in male spontaneously hypertensive rats contributes to delayed recovery of renal function following renal ischemia perfusion compared with females

Riyaz Mohamed, Gene R. Crislip, Sarah McLarnon, Qingqing Wei, Paul M. O’Connor, Jennifer C. Sullivan
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (11): 825–840.
DOI: https://doi.org/10.1042/CS20220002
Published: 01 June 2022
View article titled, Persistent vascular congestion in male spontaneously hypertensive rats contributes to delayed recovery of renal function following renal ischemia perfusion compared with females
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Articles

Promoting mitochondrial fusion in doxorubicin-induced cardiotoxicity: a novel therapeutic target for cardioprotection

Chayodom Maneechote, Thawatchai Khuanjing, Benjamin Ongnok, Apiwan Arinno, Nanthip Prathumsap, Titikorn Chunchai, Busarin Arunsak, Wichwara Nawara, Siriporn C. Chattipakorn, Nipon Chattipakorn
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (11): 841–860.
DOI: https://doi.org/10.1042/CS20220074
Published: 01 June 2022
View article titled, Promoting mitochondrial fusion in doxorubicin-induced cardiotoxicity: a novel therapeutic target for cardioprotection
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Articles

Diminished Rbfox1 increases vascular constriction by dynamically regulating alternative splicing of Ca V 1.2 calcium channel in hypertension

Miaomiao Song, Wei Hou, Atta Ul Mustafa, Pengpeng Li, Jianzhen Lei, Yingying Zhou, Li Ji, Yu Sun, Hongmei Zhou, Yinyan Xu, Juejin Wang
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (11): 803–817.
DOI: https://doi.org/10.1042/CS20220226
Published: 30 May 2022
View article titled, Diminished Rbfox1 increases vascular constriction by dynamically regulating alternative splicing of Ca V 1.2 calcium channel in hypertension
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Includes: Supplementary data
Articles

Visualization of regenerating and repairing hearts

Nevan Powers, Guo N. Huang
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (10): 787–798.
DOI: https://doi.org/10.1042/CS20211116
Published: 27 May 2022
View article titled, Visualization of regenerating and repairing hearts
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Articles

Angiotensin Receptors - Affinity and Beyond

Colin Sumners, Igor Maciel Souza Silva, U. Muscha Steckelings
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (10): 799–802.
DOI: https://doi.org/10.1042/CS20220024
Published: 27 May 2022
View article titled, Angiotensin Receptors - Affinity and Beyond
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Articles

Differential effects of cyclo-oxygenase 1 and 2 inhibition on angiogenesis inhibitor-induced hypertension and kidney damage

In Collection
Cardiovascular-Oncology
Katrina M. Mirabito Colafella, Daan C.H. van Dorst, Rugina I. Neuman, Leni van Doorn, Karla Bianca Neves, Augusto C. Montezano, Ingrid M. Garrelds, Richard van Veghel, René de Vries, Estrellita Uijl, Marian C. Clahsen-van Groningen, Hans J. Baelde, Anton H. van den Meiracker, Rhian M. Touyz, Willy Visser, A.H. Jan Danser, Jorie Versmissen
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (9): 675–694.
DOI: https://doi.org/10.1042/CS20220182
Published: 10 May 2022
View article titled, Differential effects of cyclo-oxygenase 1 and 2 inhibition on angiogenesis inhibitor-induced hypertension and kidney damage
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Includes: Supplementary data
Articles

Small extracellular vesicles derived from patients with persistent atrial fibrillation exacerbate arrhythmogenesis via miR-30a-5p

Dasom Mun, Hyoeun Kim, Ji-Young Kang, Nuri Yun, Young-Nam Youn, Boyoung Joung
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (8): 621–637.
DOI: https://doi.org/10.1042/CS20211141
Published: 27 April 2022
View article titled, Small extracellular vesicles derived from patients with persistent atrial fibrillation exacerbate arrhythmogenesis via miR-30a-5p
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Includes: Supplementary data
Articles

Mechanism-based strategies to prevent salt sensitivity and salt-induced hypertension

Theodore W. Kurtz, Michal Pravenec, Stephen E. DiCarlo
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (8): 599–620.
DOI: https://doi.org/10.1042/CS20210566
Published: 22 April 2022
View article titled, Mechanism-based strategies to prevent salt sensitivity and salt-induced hypertension
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Articles

Ebselen abolishes vascular dysfunction in influenza A virus-induced exacerbations of cigarette smoke-induced lung inflammation in mice

Kurt Brassington, Stanley M.H. Chan, Simone N. De Luca, Aleksandar Dobric, Suleman A. Almerdasi, Kevin Mou, Huei Jiunn Seow, Osezua Oseghale, Steven Bozinovski, Stavros Selemidis, Ross Vlahos
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (8): 537–555.
DOI: https://doi.org/10.1042/CS20211090
Published: 21 April 2022
View article titled, Ebselen abolishes vascular dysfunction in influenza A virus-induced exacerbations of cigarette smoke-induced lung inflammation in mice
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Articles

Metabolism in atherosclerotic plaques: immunoregulatory mechanisms in the arterial wall

Maria J. Forteza, Daniel F.J. Ketelhuth
Journal: Clinical Science
Clin Sci (Lond) (2022) 136 (6): 435–454.
DOI: https://doi.org/10.1042/CS20201293
Published: 29 March 2022
View article titled, Metabolism in atherosclerotic plaques: immunoregulatory mechanisms in the arterial wall
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