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Issues
January 2022
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Cover Image
Cover Image
The cover image of this issue of Clinical Science (volume 136, issue 2) features an image from Shahzadi et al., showing the control (left panel) and Nicotinamide riboside kinase-2 (NRK-2) knockout (right panel) whole hearts from mice subjected to Sham (top) or trans-aortic constriction (bottom) surgeries. This study identified the critical roles of integrin-binding protein NRK-2 in the regulation of the JNK pathway and dilatative cardiac remodelling under chronic pressure-overload.
ISSN 0143-5221
EISSN 1470-8736
In this Issue
Research Articles
Nicotinamide riboside kinase-2 inhibits JNK pathway and limits dilated cardiomyopathy in mice with chronic pressure overload
Clin Sci (Lond) (2022) 136 (2): 181–196.