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Volume 135, Issue 7
April 2021
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    The cover of this issue of Clinical Science (volume 135, issue 7) features an immunohistochemistry image of end-binding protein 2 (EB2) expression in hepatocellular carcinoma (HCC) tissues. EB2 is frequently up-regulated in HCC and plays a critical role in promoting HCC progression. Read more about this in the study by Zhong et al.
ISSN 0143-5221
EISSN 1470-8736
In this Issue

Review articles

Clonal haematopoiesis of indeterminate potential: intersections between inflammation, vascular disease and heart failure
Leanne Mooney; Carl S. Goodyear; Tamir Chandra; Kristina Kirschner; Mhairi Copland; Mark C. Petrie; Ninian N. Lang
Clin Sci (Lond) (2021) 135 (7): 991–1007.
View Articletitled, Clonal haematopoiesis of indeterminate potential: intersections between inflammation, vascular disease and heart failure
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Research Articles

EB2 promotes hepatocellular carcinoma proliferation and metastasis via MAPK/ERK pathway by modulating microtubule dynamics
Fang-Jing Zhong; Yi-Ming Li; Cong Xu; Bo Sun; Ji-Long Wang; Lian-Yue Yang
Clin Sci (Lond) (2021) 135 (7): 847–864.
View Articletitled, EB2 promotes hepatocellular carcinoma proliferation and metastasis via MAPK/ERK pathway by modulating microtubule dynamics
Supplementary data
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Down-regulation of STAT3 enhanced chemokine expression and neutrophil recruitment in biliary atresia
Ming Fu; Ledong Tan; Zefeng Lin; Vincent C.H. Lui; Paul K.H. Tam; Jonathan R. Lamb; Yan Zhang; Huimin Xia; Ruizhong Zhang; Yan Chen
Clin Sci (Lond) (2021) 135 (7): 865–884.
View Articletitled, Down-regulation of STAT3 enhanced chemokine expression and neutrophil recruitment in biliary atresia
Supplementary data
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Promyelocytic leukemia protein promotes the phenotypic switch of smooth muscle cells in atherosclerotic plaques of human coronary arteries
Weronika Karle; Samuel Becker; Philipp Stenzel; Christoph Knosalla; Günter Siegel; Oliver Baum; Andreas Zakrzewicz; Janine Berkholz
Clin Sci (Lond) (2021) 135 (7): 887–905.
View Articletitled, Promyelocytic leukemia protein promotes the phenotypic switch of smooth muscle cells in atherosclerotic plaques of human coronary arteries
Supplementary data
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CRIP1 expression in monocytes related to hypertension
Olga Schweigert; Julia Adler; Natalie Längst; Dylan Aïssi; Jorge Duque Escobar; Teng Tong; Christian Müller; David-Alexandre Trégouët; Robert Lukowski; Tanja Zeller
Clin Sci (Lond) (2021) 135 (7): 911–924.
View Articletitled, CRIP1 expression in monocytes related to hypertension
Supplementary data
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Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury
Yanjun Liu; Jiacheng Li; Liping Liao; Heming Huang; Shijie Fan; Rong Fu; Jing Huang; Cuicui Shi; Liang Yu; Kai-xian Chen; Yuan-yuan Zhang; Cheng Luo; Guang-ming Li
Clin Sci (Lond) (2021) 135 (7): 925–941.
View Articletitled, Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury
Supplementary data
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Angiotensin II up-regulates sodium-glucose co-transporter 2 expression and SGLT2 inhibitor attenuates Ang II-induced hypertensive renal injury in mice
Kana N. Miyata; Chao-Sheng Lo; Shuiling Zhao; Min-Chun Liao; Yuchao Pang; Shiao-Ying Chang; Junzheng Peng; Matthias Kretzler; Janos G. Filep; Julie R. Ingelfinger; Shao-Ling Zhang; John S.D. Chan
Clin Sci (Lond) (2021) 135 (7): 943–961.
View Articletitled, Angiotensin II up-regulates sodium-glucose co-transporter 2 expression and SGLT2 inhibitor attenuates Ang II-induced hypertensive renal injury in mice
Supplementary data
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Genetic and epigenetic regulation of the non-muscle myosin light chain kinase isoform by lung inflammatory factors and mechanical stress
Xiaoguang Sun; Belinda L. Sun; Saad Sammani; Tadeo Bermudez; Steven M. Dudek; Sara M. Camp; Joe G.N. Garcia
Clin Sci (Lond) (2021) 135 (7): 963–977.
View Articletitled, Genetic and epigenetic regulation of the non-muscle myosin light chain kinase isoform by lung inflammatory factors and mechanical stress
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IGF2 deficiency causes mitochondrial defects in skeletal muscle
Yiyi Zhu; Weiwei Gui; Bowen Tan; Ying Du; Jiaqiang Zhou; Fang Wu; Hong Li; Xihua Lin
Clin Sci (Lond) (2021) 135 (7): 979–990.
View Articletitled, IGF2 deficiency causes mitochondrial defects in skeletal muscle
Supplementary data
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Correspondence

Brain angiotensin suppression in the DOCA-salt model: reversal by angiotensinogen small interfering RNA?
Estrellita Uijl; A.H. Jan Danser
Clin Sci (Lond) (2021) 135 (7): 885–886.
View Articletitled, Brain angiotensin suppression in the DOCA-salt model: reversal by angiotensinogen small interfering RNA?
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Letter to the Editor: Brain renin–angiotensin system and liver-directed siRNA targeted to angiotensinogen
Carlos M. Ferrario; Leanne Groban; Hao Wang; Sarfaraz Ahmad
Clin Sci (Lond) (2021) 135 (7): 907–910.
View Articletitled, Letter to the Editor: Brain renin–angiotensin system and liver-directed siRNA targeted to angiotensinogen
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Submit your work
Maintaining energy provision in the heart: the creatine kinase system in ischaemia–reperfusion injury and chronic heart failure
Participation of the spleen in the neuroinflammation after pilocarpine-induced status epilepticus: Implications for epileptogenesis and epilepsy
Alveolar epithelial cells of lung fibrosis patients are susceptible to severe virus-induced injury
Correction: The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease
Inflammatory liver diseases and susceptibility to sepsis
  • Online ISSN 1470-8736
  • Print ISSN 0143-5221

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