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Issues
October 2021
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Cover Image
Cover Image
The cover of this issue of Clinical Science (volume 135, issue 20) features a confocal image showing alpha-1 adrenergic receptor (green) in mouse kidney tubules and vessels 24 hours after sepsis onset. The higher density of alpha-1 receptor may explain the anomalous renal vasoconstriction leading to sepsis acute kidney injury. Read more in the article by Rosales et al.
ISSN 0143-5221
EISSN 1470-8736
In this Issue
Editorial
Review Articles
Updates in deep learning research in ophthalmology
Wei Yan Ng; Shihao Zhang; Zhaoran Wang; Charles Jit Teng Ong; Dinesh V. Gunasekeran; Gilbert Yong San Lim; Feihui Zheng; Shaun Chern Yuan Tan; Gavin Siew Wei Tan; Tyler Hyungtaek Rim; Leopold Schmetterer; Daniel Shu Wei Ting
Clin Sci (Lond) (2021) 135 (20): 2357–2376.
Research Articles
Dynamics of GRK2 in the kidney: a putative mechanism for sepsis-associated kidney injury
Thiele Osvaldt Rosales; Verônica Vargas Horewicz; Marcella Amorim Ferreira; Geisson Marcos Nardi; Jamil Assreuy
Clin Sci (Lond) (2021) 135 (20): 2341–2356.
High-volume endurance exercise training stimulates hematopoiesis by increasing ACE NH2-terminal activity
Flávio de Castro Magalhães; Tiago Fernandes; Vinícius Bassaneze; Katt Coelho Mattos; Isolmar Schettert; Fabio Luiz Navarro Marques; José Eduardo Krieger; Roberto Nava; Valério Garrone Barauna; Oliveira Edilamar Menezes
Clin Sci (Lond) (2021) 135 (20): 2377–2391.
Chronic activation of AMP-activated protein kinase leads to early-onset polycystic kidney phenotype
Laura Wilson; Alice E. Pollard; Lucy Penfold; Phillip J. Muckett; Chad Whilding; Mohammad Bohlooly-Y.; Patricia Wilson; David Carling
Clin Sci (Lond) (2021) 135 (20): 2393–2408.
Xanthine oxidase inhibitor febuxostat reduces atrial fibrillation susceptibility by inhibition of oxidized CaMKII in Dahl salt-sensitive rats
DongZhu Xu; Nobuyuki Murakoshi; Kazuko Tajiri; Feng Duo; Yuta Okabe; Yoshiko Murakata; Zixun Yuan; Siqi Li; Kazuhiro Aonuma; Zonghu Song; Yuzuno Shimoda; Haruka Mori; Akira Sato; Akihiko Nogami; Kazutaka Aonuma; Masaki Ieda
Clin Sci (Lond) (2021) 135 (20): 2409–2422.
Osteoprotegerin regulates vascular function through syndecan-1 and NADPH oxidase-derived reactive oxygen species
Rhéure Alves-Lopes; Karla Bianca Neves; Anastasiya Strembitska; Adam P. Harvey; Katie Y. Harvey; Hiba Yusuf; Susan Haniford; Ross T. Hepburn; Jennifer Dyet; Wendy Beattie; Laura Haddow; John McAbney; Delyth Graham; Augusto C. Montezano
Clin Sci (Lond) (2021) 135 (20): 2429–2444.