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Issues
January 2021
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Cover Image
Cover Image
This cover of this issue of Clinical Science (volume 135, issue 2) shows coronary perfusion during a cardiac stress test determined by angiography in diabetic rats treated with metoprolol. In their research article, Pearson et al. show that two classes of beta blocker drugs improve coronary microvessel endothelial function and nitric oxide sensitivity, alleviating the coronary dysfunction caused by a high salt intake in combination with insulin resistance.
ISSN 0143-5221
EISSN 1470-8736
In this Issue
Review Articles
Host cell glutamine metabolism as a potential antiviral target
Sandro Massao Hirabara; Renata Gorjao; Adriana Cristina Levada-Pires; Laureane Nunes Masi; Elaine Hatanaka; Maria Fernanda Cury-Boaventura; Eliane Borges da Silva; Laiane Cristina dos Santos-Oliveira; Vinicius Leonardo Sousa Diniz; Tamires Afonso Duarte Serdan; Vivian Araujo Barbosa de Oliveira; Diego Ribeiro de Souza; Raquel Bragante Gritte; Talita Souza-Siqueira; Raquel Freitas Zambonatto; Tania Cristina Pithon-Curi; Roberto Barbosa Bazotte; Philip Newsholme; Rui Curi
Clin Sci (Lond) (2021) 135 (2): 305–325.
ACE2/Ang-(1-7)/Mas1 axis and the vascular system: vasoprotection to COVID-19-associated vascular disease
Clin Sci (Lond) (2021) 135 (2): 387–407.
Research Articles
No evidence for brain renin–angiotensin system activation during DOCA-salt hypertension
Estrellita Uijl; Liwei Ren; Katrina M. Mirabito Colafella; Richard van Veghel; Ingrid M. Garrelds; Oliver Domenig; Marko Poglitsch; Ivan Zlatev; Jae B. Kim; Stephen Huang; Lauren Melton; Ewout J. Hoorn; Don Foster; A.H. Jan Danser
Clin Sci (Lond) (2021) 135 (2): 259–274.
β-blockade prevents coronary macro- and microvascular dysfunction induced by a high salt diet and insulin resistance in the Goto–Kakizaki rat
James T. Pearson; Hamish P. Thambyah; Mark T. Waddingham; Tadakatsu Inagaki; Vijayakumar Sukumaran; Jennifer P. Ngo; Connie P.C. Ow; Takashi Sonobe; Yi Ching Chen; Amanda J. Edgley; Yutaka Fujii; Cheng-Kun Du; Dong-Yun Zhan; Keiji Umetani; Darren J. Kelly; Hirotsugu Tsuchimochi; Mikiyasu Shirai
Clin Sci (Lond) (2021) 135 (2): 327–346.
Sepsis plasma-derived exosomal miR-1-3p induces endothelial cell dysfunction by targeting SERP1
Clin Sci (Lond) (2021) 135 (2): 347–365.
Gastrin, via activation of PPARα, protects the kidney against hypertensive injury
Daqian Gu; Dandong Fang; Mingming Zhang; Jingwen Guo; Hongmei Ren; Xinyue Li; Ziyue Zhang; Donghai Yang; Xue Zou; Yukai Liu; Wei Eric Wang; Gengze Wu; Pedro A. Jose; Yu Han; Chunyu Zeng
Clin Sci (Lond) (2021) 135 (2): 409–427.
