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July 2019
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In the latest issue of Clinical Science (volume 133, issue 13), Lai et al. identify pseudogene PTENP1 as a potential target in aortic dissection or aortic aneurysm intervention. They found that after the downregulation of pseudogene PTENP1, nuclear division of phopho-H3 in smooth muscle cells significantly increased, as shown in this immunofluorescence stain.
ISSN 0143-5221
EISSN 1470-8736
In this Issue
Research Articles
Obesity-induced type 2 diabetes impairs neurological recovery after stroke in correlation with decreased neurogenesis and persistent atrophy of parvalbumin-positive interneurons
Hiranya Pintana; Grazyna Lietzau; Ingrid Lovise Augestad; Fausto Chiazza; Thomas Nyström; Cesare Patrone; Vladimer Darsalia
Clin Sci (Lond) (2019) 133 (13): 1367–1386.
MicroRNA-302d promotes the proliferation of human pluripotent stem cell-derived cardiomyocytes by inhibiting LATS2 in the Hippo pathway
Fei Xu; Jingcheng Yang; Jun Shang; Feng Lan; Miaomiao Li; Leming Shi; Li Shen; Yongming Wang; Junbo Ge
Clin Sci (Lond) (2019) 133 (13): 1387–1399.
Ovarian cancer-derived exosomes promote tumour metastasis in vivo: an effect modulated by the invasiveness capacity of their originating cells
Mona Alharbi; Andrew Lai; Dominic Guanzon; Carlos Palma; Felipe Zuñiga; Lewis Perrin; Yaowu He; John D. Hooper; Carlos Salomon
Clin Sci (Lond) (2019) 133 (13): 1401–1419.
Enhanced endoplasmic reticulum and mitochondrial stress in abdominal aortic aneurysm
Miquel Navas-Madroñal; Cristina Rodriguez; Modar Kassan; Joan Fité; José R. Escudero; Laia Cañes; José Martínez-González; Mercedes Camacho; María Galán
Clin Sci (Lond) (2019) 133 (13): 1421–1438.
The pseudogene PTENP1 regulates smooth muscle cells as a competing endogenous RNA
Yanxian Lai; Jianyong Li; Lintao Zhong; Xiang He; Xiaoyun Si; Yili Sun; Yanmei Chen; Jiayuan Zhong; Yinlan Hu; Bing Li; Wangjun Liao; Cheng Liu; Yulin Liao; Jiancheng Xiu; Jianping Bin
Clin Sci (Lond) (2019) 133 (13): 1439–1455.
A novel lncRNA NR4A1AS up-regulates orphan nuclear receptor NR4A1 expression by blocking UPF1-mediated mRNA destabilization in colorectal cancer
Xina Xie; Jiatian Lin; Jianlan Liu; Meihui Huang; Yuantang Zhong; Bin Liang; Xuhong Song; Songgang Gu; Xiaolan Chang; Dongyang Huang; Aifa Tang
Clin Sci (Lond) (2019) 133 (13): 1457–1473.
Impact of ET-1 and sex in glomerular hyperfiltration in humanized sickle cell mice
Clin Sci (Lond) (2019) 133 (13): 1475–1486.
CircRNA-104718 acts as competing endogenous RNA and promotes hepatocellular carcinoma progression through microRNA-218-5p/TXNDC5 signaling pathway
Clin Sci (Lond) (2019) 133 (13): 1487–1503.
Nicotinamide riboside promotes autolysosome clearance in preventing doxorubicin-induced cardiotoxicity
Dong Zheng; Yi Zhang; Ming Zheng; Ting Cao; Grace Wang; Lulu Zhang; Rui Ni; Joseph Brockman; Huiting Zhong; Guo-Chang Fan; Tianqing Peng
Clin Sci (Lond) (2019) 133 (13): 1505–1521.
Ergosterol attenuates cigarette smoke extract-induced COPD by modulating inflammation, oxidative stress and apoptosis in vitro and in vivo
Clin Sci (Lond) (2019) 133 (13): 1523–1536.