The Effect of Chronic Sodium Loading and Sodium Restriction on Plasma and Renal Concentrations of Prostaglandin a in Normal Wistar and Spontaneously Hypertensive Aoki Rats

Zusman, R. M.; Forman, B. H.; Schneider, G.; Caldwell, B. V.; Speroff, L.; Mulrow, P. J.

doi:10.1042/cs045325s

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Conference Abstract| August 01 1973

The Effect of Chronic Sodium Loading and Sodium Restriction on Plasma and Renal Concentrations of Prostaglandin a in Normal Wistar and Spontaneously Hypertensive Aoki Rats

R. M. Zusman;

R. M. Zusman

1Department of Obstetrics and Gynecology and Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn., U.S.A.

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B. H. Forman;

B. H. Forman

2Department of Obstetrics and Gynecology and Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn., U.S.A.

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G. Schneider;

G. Schneider

3Department of Obstetrics and Gynecology and Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn., U.S.A.

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B. V. Caldwell;

B. V. Caldwell

4Department of Obstetrics and Gynecology and Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn., U.S.A.

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L. Speroff;

L. Speroff

5Department of Obstetrics and Gynecology and Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn., U.S.A.

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P. J. Mulrow

6Department of Obstetrics and Gynecology and Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn., U.S.A.

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Author and article information

Publisher: Portland Press Ltd

1994

Clin Sci Mol Med (1973) 45 (s1): 325s–329s.

https://doi.org/10.1042/cs045325s

1. In normal and hypertensive rats prostaglandin A (PGA) in plasma and kidney increased on low sodium intake and decreased on high sodium intake.

2. Plasma and renal concentrations of PGA were higher in spontaneously hypertensive rats than in normal Wistar rats in each dietary group.

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