Absence of Activation in Vitro of Renin in Rat Plasma

1. Rat plasma was subjected at 4°C to various treatments known to convert inactive renin into its active form in human plasma.

2. No statistical differences in plasma renin concentration were found when the levels after the various treatments were compared with that of untreated rat plasma.

3. It is concluded that, in contrast to human plasma, no inactive form of renin is present in rat plasma.