1. The anti-hypertensive effect of atenolol was greater than that of bendrofluazide.

2. The change in systolic blood pressure caused by bendrofluazide showed a significant inverse correlation with the plasma renin concentration (r = −0·47; P < 0·01).

3. The correlation between the change in systolic blood pressure caused by atenolol and the plasma renin concentration was not significant (r = 0·28; 0·1 > P > 0·05).

4. Plasma renin concentration was unaffected by atenolol.

Keywords:
atenolol, bendrofluazide, hypertension, plasma renin concentration, β-receptor blockade
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© 1976 The Biochemical Society and the Medical Research Society
1976
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