1. Sixteen plasma amino acids were measured serially in an experimental model of acute hepatic failure produced in the pig by devascularization of the liver.

2. Significant increases in the concentration of glycine, alanine and methionine were observed.

3. Altered concentrations in plasma of neutral amino acids which compete with tryptophan for transport into the brain had no apparent influence on brain tryptophan concentration.

Keywords:
amino acids, fatty acids (non-esterified), tryptophan, hepatic coma
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© 1974 The Biochemical Society and the Medical Research Society
1974
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