...Riva Mary Rani; Superior Syngkli; Joplin Nongkhlaw; Bidyadhar Das Background: Glycerol kinase (GK; EC 2.7.1.30) facilitates the entry of glycerol into pathways of glucose and triglyceride metabolism and may play a potential role in Type 2 diabetes mellitus (T2DM). However, the detailed regulatory...

...Guan Wang; Mengyuan Li; Shuo Yu; Mengqi Guan; Shiqi Ma; Zhen Zhong; Yihui Guo; Xiangyang Leng; Haipeng Huang Objective: To explore the proteomics profiles of hepatocytes of mice treated with acupuncture for type 2 diabetes mellitus (T2DM) with non-alcoholic fatty liver disease (NAFLD). Methods: We...

...Kaibo Lyu; Wei Yue; Junhua Ran; Yunjuan Liu; Xueliang Zhu Background: The study was aimed to investigate the potential therapeutic effect of Mori folium aqueous extracts (MFAE) on type 2 diabetes mellitus (T2DM) in vivo . Methods and results: A rat model of T2DM was established with the combination...

... inflammatory symptoms, including blood clotting and acute respiratory distress. Death due to COVID-19 shows a steep rise in relation to age. Comorbidities such as type 2 diabetes mellitus (T2DM), hypertension, and cardiovascular disease also increase susceptibility. It has been reported that T-cell regulatory...

...Jieyuan Cui; Xiaolin Zhang; Cheng Guo; Lin Zhang Objectives: To evaluate the effects of the single-nucleotide polymorphism (SNP) rs1800795 in interieukin-6 (IL-6) gene on diabetic microvascular complications of Type 2 diabetes mellitus (T2DM), using statistical meta-analysis. Methods: Literature...

...Ting Huang; Li Wang; Mei Bai; Jianwen Zheng; Dongya Yuan; Yongjun He; Yuhe Wang; Tianbo Jin; Wei Cui Background: The present study aimed to investigate the roles of insulin related gene IGF2BP2, HMG20A , and HNF1B variants in the susceptibility of Type 2 diabetes mellitus (T2DM), and to identify...

... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Gamma-aminobutyric acid type B Type 2 diabetes mellitus Spatial cognitive...

...Huanping Wang; Huizhen Chen; Yang Gao; Shengju Wang; Xian Wang; Xiaomei Tang; Wei Fang; Xiaoyan Shi; Jia Yao; Qiu Chen Objective: Depression is a common complication in Type 2 diabetes mellitus (T2DM); however, it has long been underrecognized and undertreated. In the present study, we aimed...

... of the immune system and host’s metabolism. We aimed to characterize the gut microbiota of Tunisian participants with and without diabetes. We enrolled ten participants with type 1 diabetes mellitus (T1DM), ten patients with type 2 diabetes mellitus (T2DM), and 11 subjects without diabetes. Bacteria...

...Feng Tian; Zhigang Zheng; Damin Zhang; Si He; Jie Shen Type 2 diabetes mellitus (T2DM) complicated with non-alcoholic fatty liver disease (NAFLD) is difficult to treat. The present study explored the efficacy of (liraglutide) Lira in treating T2DM complicated with NAFLD. A total of 127 patients...

..., inflammation, and type 2 diabetes mellitus (T2DM). Recent evidence has indicated that SFRP5 is capable of stimulating adipocyte differentiation via inhibition of the Wnt/β-catenin signaling pathway. In addition, SFRP5 binding with wingless-type murine mammary tumor virus integration site family, member 5A...

...Chenyi Li; Danjun Fan ATP-binding cassette transporter A1 (ABCA1) is associated with serum high-density lipoprotein (HDL) levels. Several studies have demonstrated that individuals with a high HDL cholesterol level have a reduced risk of incident type 2 diabetes mellitus (T2DM). Therefore, we...

...Xiao-Jun Cai; Lei Wang; Chun-Mei Hu The present study was conducted with the aim being to investigate the effect γ-aminobutyric acid type B (GABAB) receptor activation have on spatial cognitive function and hippocampal neurones found in the rat models of type 2 diabetes mellitus (T2DM). T2DM rat...

...Xue Han; Ye Wu; Xin Liu; Lu Ma; Tingting Lv; Qi Sun; Wenli Xu; Suli Zhang; Ke Wang; Wen Wang; Xinliang Ma; Huirong Liu To determine the effect of adiponectin (APN) on the coronary no-reflow (NR) injury in rats with Type 2 diabetes mellitus (T2DM), 80 male Sprague–Dawley rats were fed with a high...

... of cardiovascular disease (CVD) and mortality. The crucial role of heat-shock proteins (HSPs) on renal function in patients with DN has been well documented. The present study was aimed to understand the association of HSP-70 gene variants on the susceptibility of Type 2 Diabetes Mellitus (T2DM) and DN. A total...