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1-38 of 38
Keywords: susceptibility
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Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (10): BSR20211338.
Published: 19 October 2021
... interaction =0.025) influencing individual’s genetic susceptibility to GDM. The rs2134095 T>C is significantly associated with the risk of GDM by effect of a single locus and/or complex joint gene–gene and gene–environment interactions. Larger sample-size and different population studies are required...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (4): BSR20204136.
Published: 22 April 2021
... controls to assess the association of genetic polymorphisms in miR-143/145 and the KRAS 3′ untranslated region (3′UTR) with susceptibility to CRC and patients’ survival. In addition, genetic variations of genomic regions located from 500 bp upstream to 500 bp downstream of the miR-143/miR-145 gene...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (2): BSR20201158.
Published: 17 February 2021
... for CC/TC vs. TT). In addition, gene–gene interaction analysis showed that rs11614913 TC/3746444 AA and rs11614913 CC/rs3746444 AA could also reduce the susceptibility to NSCLC (rs11614913 TC/rs3746444 AA vs. rs11614913 TT/rs3746444 AA, P =0.001, power = 0.912 and rs11614913 CC/rs3746444 AA vs...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (12): BSR20203245.
Published: 26 November 2020
...Yongzhong Shi; Wei Xu; Xia Zhang The association between the hOGG1 Ser326Cys polymorphism and gynecologic cancer susceptibility is inconclusive. We performed a comprehensive meta-analysis to precisely estimate of the impact of the hOGG1 Ser326Cys polymorphism on gynecologic cancer susceptibility...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20192051.
Published: 23 October 2020
... . The findings did not support an association between FGFR4 rs351855 polymorphism and overall cancer susceptibility in heterozygous (OR = 0.97, 95% CI = 0.87–1.07, P =0.514, AG vs GG), homozygous (OR = 1.14, 95% CI = 0.95–1.37, P =0.166, AA vs GG), dominant (OR = 0.98, 95% CI = 0.87–1.10, P =0.686, AG+AA vs...
Articles
Xu Chao, Xuesong Feng, Hailong Shi, Yuewen Wang, Lanlan Wang, Haiyu Shen, Qing Zha, Yanni Chen, Chao Jiang
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR20193312.
Published: 28 August 2020
..., P =3.83E-07); however, the CA genotype of rs7318578 significantly decreased the risk of liver cancer (OR = 0.61, 95% CI: 0.45–0.83, P =0.001, compared with those with the AA genotype. Our findings indicated that MIR17HG polymorphism (rs7318578) contributes to liver cancer susceptibility...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR20193141.
Published: 03 August 2020
...Shouquan Wu; Xiangmin Liu; Ling Chen; Yu Wang; Miaomiao Zhang; Minggui Wang; Jian-Qing He Genetic polymorphisms for tuberculosis (TB) susceptibility have been researched by some studies, but few have studied multiple innate immunity genes associated with TB. Evidence suggests that the toll-like...
Articles
Fei Liu, Jixiao Zeng, Deli Zhu, Xiaogang Xu, Menglong Lan, Mengmeng Wang, Jinglu Zhao, Huimin Xia, Yan Zhang, Ruizhong Zhang
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20200068.
Published: 21 July 2020
... of participants in liver fibrosis, the overexpression of PDGFA through DNA hypomethylation may lead to the development of BA, but the pathogenesis is still unclear. We conducted a large case–control cohort to investigate the association of genetic variants in PDGFA with BA susceptibility in the Southern Chinese...
Includes: Supplementary data
Articles
Ting Huang, Li Wang, Mei Bai, Jianwen Zheng, Dongya Yuan, Yongjun He, Yuhe Wang, Tianbo Jin, Wei Cui
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20193955.
Published: 28 May 2020
...Ting Huang; Li Wang; Mei Bai; Jianwen Zheng; Dongya Yuan; Yongjun He; Yuhe Wang; Tianbo Jin; Wei Cui Background: The present study aimed to investigate the roles of insulin related gene IGF2BP2, HMG20A , and HNF1B variants in the susceptibility of Type 2 diabetes mellitus (T2DM), and to identify...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20193989.
Published: 11 May 2020
... in the miRNA functional region was inextricably linked to tumor susceptibility. In the present study, we investigated the susceptibility between miR-618 rs2682818 C>A and Hirschsprung disease (HSCR) in the Southern Chinese population (1470 patients and 1473 controls). Odds ratios (ORs) and 95% confidence...
Articles
Juxiang Wang, Susu Lou, Xiaokai Huang, Yixiao Mo, Zhen Wang, Jinhong Zhu, Xiaoqian Tian, Jiandong Shi, Haixia Zhou, Jing He, Jichen Ruan
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20194202.
Published: 28 February 2020
... and Wilms tumor susceptibility through genotyping two important functional polymorphisms ( miR34b/c rs4938723 T>C and TP53 rs1042522 C>G) in 183 cases and 603 controls. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) derived from the logistic regression analysis were used to assess...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20194229.
Published: 20 February 2020
... HCC susceptibility. The relationship warrants a further assessment. The criteria for exclusion were as following: (1) publications incompatible with HWE; (2) overlapping data; (3) not case–control study design and (4) only focusing on the relationship of MTHFR rs1801133 polymorphism with HCC...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (12): BSR20192452.
Published: 04 December 2019
... studies with 26835 cancer cases and 37069 controls from the 1186 retrieved articles. There is an enhanced susceptibility for bladder cancer cases under T vs. C [ P =0.004; OR (95% CI) = 1.25 (1.07, 1.45)], TT vs. CC [ P =0.001; 1.68 (1.25, 2.26)], CT+TT vs. CC [ P =0.016; 1.26 (1.04, 1.53)], and TT vs. CC...
Includes: Supplementary data
Articles
Jing Tao, Mayila Abudoukelimu, Xin Shen, Jun Liu, Feng-xia Wang, Jie Yuan, Pei-Pei Gu, Wei Zhu, Xiao-tian Zhang, Zhao Wang, Yi-tong Ma, Guo-qing Li
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (12): BSR20190498.
Published: 28 November 2019
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . INSIG1 gene obesity polymorphism susceptibility Obesity is one of the major risk factors of chronic and metabolic diseases and the prevalence of obesity is increasing worldwide [ 1–4 ]. Globally...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (11): BSR20192517.
Published: 12 November 2019
...Sheng Zhang; Jing Lin; Jiakai Jiang; Yu Chen; Weifeng Tang; Longgen Liu Polymorphisms in one-carbon metabolism genes may influence the susceptibility to hepatocellular carcinoma (HCC). In the present study, we studied methylenetetrahydrofolate reductase ( MTHFR ) tagging polymorphisms in 584 HCC...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (10): BSR20192529.
Published: 18 October 2019
... and Wilms tumor susceptibility. The association between the PHOX2B rs28647582 T>C polymorphism and Wilms tumor susceptibility was assessed by odds ratios (ORs) and 95% confidence intervals (CIs). Our results indicated that PHOX2B rs28647582 T>C polymorphism did not significantly alter Wilms tumor...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (10): BSR20192091.
Published: 15 October 2019
... a lower susceptibility to glioma in males (OR = 0.68, P =0.034), while rs4598633 variant with a higher risk in females (OR = 1.66, P =0.016). Additionally, rs7115578 AG genotype represented a poorer prognosis of glioma (HR = 1.24, P =0.033) and astrocytoma (log-rank P =0.037, HR = 1.31, P =0.036...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190708.
Published: 12 July 2019
...Ming-li Yang; Zhe Huang; Li-na Wu; Rong Wu; Han-xi Ding; Ben-gang Wang Background: Single-nucleotide polymorphisms (SNPs) in lncRNAs could be biomarkers for susceptibility to colorectal cancer (CRC), but the association of PCAT1 polymorphisms and CRC susceptibility is yet to be studied. Methods...
Includes: Supplementary data
Articles
Chunlei Zhou, Yingzi Tang, Jinhong Zhu, Lili He, Jinghang Li, Yizhen Wang, Haixia Zhou, Jing He, Haiyan Wu
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (6): BSR20181907.
Published: 07 June 2019
...-miRNA) have shown to associate with cancer susceptibility, including neuroblastoma. Three precursor miRNA (pre-miRNA) SNPs ( pre-miR-146a rs2910164, pre-miR-149 rs2292832 and pre-miR-196a2 rs11614913) were found to contribute to pathogenesis of various diseases. Here, to evaluate the association among...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20182008.
Published: 14 May 2019
... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . asthma CHI3L1 function polymorphism susceptibility Asthma is a complex airway disorder characterized by chronic...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20180573.
Published: 07 May 2019
.... The expression and function of lncRNAs could be affected by single nucleotide polymorphisms (SNPs), which are associated with cancer susceptibility and prognosis. However, no investigation has focused on the association between HOTTIP SNPs and CRC. The aim of the present study was to explore the association...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (4): BSR20182292.
Published: 17 April 2019
... of Xinjiang Medical University and conducted according to the standards of the Declaration of Helsinki. Written informed consent was obtained from each participant. acute coronary syndrome NFKB1 gene polymorphism susceptibility ACS is a syndrome due to decreased blood flow in the coronary...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (3): BSR20181809.
Published: 19 March 2019
...Yan Chen; Xiaoxue Qi; Ce Bian; Chen Ling; Tao Yi; Xiyan Mu; Xia Zhao The role of forkhead box P3 (FOXP3) protein in tumorigenesis has long been controversial and existing data on the association between FOXP3 gene polymorphisms and cancer susceptibility were inconsistent. Here, we conducted a meta...
Articles
Yong-Tao Wang, Buamina Maitusong, Yi-Tong Ma, Zhen-Yan Fu, Yi-Ning Yang, Xiang Ma, Xiao-Mei Li, Fen Liu, Bang-Dang Chen
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (2): BSR20182129.
Published: 26 February 2019
... artery disease polymorphism susceptibility Coronary artery disease (CAD) is a common cardiovascular disease and has been the leading cause of death in the world wide [ 1 ]. CAD is recognized as a complex disease and is caused by multiple risk factors, including smoking, chronic inflammation...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (2): BSR20181896.
Published: 05 February 2019
...Min Zhang; Ling-Long Peng; Xue-Lei Ji; Hai-Bing Yang; Ri-Sheng Zha; Guo-Ping Gui Studies investigating association between tumor necrosis factor (TNF) gene polymorphisms and silicosis susceptibility report conflicting results. The aim of this meta-analysis was to assess association between TNF gene...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20181891.
Published: 22 January 2019
... of 90% in developed countries [ 7–9 ]. However, nearly 25% of Wilms tumor patients relapse [ 10 , 11 ]. Moreover, disappointing events such as 25% of survivors with severe chronic health conditions and high treatment cost await to be solved. polymorphism rs1042522 C>G susceptibility TP53...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20181770.
Published: 15 January 2019
... was conducted to derive a more precise estimation of the association between MTR A2756G polymorphism and genetic susceptibility to pediatric ALL. The PubMed, Embase, Google Scholar, Web of Science, ScienceDirect, Wanfang Databases and China National Knowledge Infrastructure were systematically searched...
Articles
Raju K. Mandal, Munawwar Ali Khan, Arif Hussain, Naseem Akhter, Arshad Jawed, Sajad A. Dar, Mohd Wahid, Aditya K. Panda, Mohtashim Lohani, Bhartendu N. Mishra, Shafiul Haque
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20181052.
Published: 15 January 2019
... the populations. The association of – 308 G>A polymorphism of TNF -α gene with increased or decreased susceptibility to CRC is still debatable [ 15–29 ]. The prime reasons for the inconsistent results among multiple reports may be the different ethnicity of the population along with small sample size...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (4): BSR20180498.
Published: 29 August 2018
.... Evidence from infections in immunocompromised patients, twin comparisons, candidate gene, and genome-wide association studies indicates that host genetic factors affect TB susceptibility [ 19–23 ]. The recent literature has focussed on the role of the host innate immune system in influencing...
Articles
Li Zhang, Jinxin Wang, Di Che, Yanfei Wang, Xing Rong, Lei Pi, Yufen Xu, Wei Li, Ping Huang, Maoping Chu, Xiaoqiong Gu
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (4): BSR20180749.
Published: 03 July 2018
... and Kawasaki disease susceptibility Genotype Cases ( n =532) Controls ( n =616) P * Crude OR (95% CI) P Adjusted OR (95% CI) † P † rs2910164 (HWE = 0.902) CC 199 (37.41) 230 (37.34) 1.00 1.00 CG 258 (48.50) 294 (47.73) 1.03 (0.80–1.33) 0.807 1.01 (0.79–1.30...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (3): BSR20180331.
Published: 27 June 2018
...) at CDKN2A locus were identified to impact on ALL susceptibility via genome wide association studies, and followed by multiple subsequent replication studies at the specific hits. Here, we conducted a systematic review and meta-analysis to re-evaluate the association of both SNPs (rs3731217 and rs3731249...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (3): BSR20180440.
Published: 21 June 2018
... model (OR = 1.20, 95% CI = 1.02–1.42, P =0.03). Our results suggest that the ERCC1 rs11615 polymorphism is associated with breast cancer susceptibility, and in particular, this increased risk of breast cancer existence in Asian population. Correspondence: Dongchun Qin ( qindongchunyfy@outlook.com...
Articles
Jue Tang, Yuanmin Qian, Jinhong Zhu, Jiao Zhang, Feng-Hua Wang, Jia-Hang Zeng, Jiang-Hua Liang, Hui Wang, Huimin Xia, Jing He, Wei Liu
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (3): BSR20180292.
Published: 22 May 2018
... regulates N-myc protein levels and plays a critical role in tumorigenesis. To investigate the association between three AURKA polymorphisms (rs1047972 C>T, rs2273535 T>A, and rs8173 G>C) and neuroblastoma susceptibility in Chinese populations, we performed this two-center case–control study...
Includes: Supplementary data
Articles
Lei Pi, Lanyan Fu, Yufen Xu, Di Che, Qiulian Deng, Xijing Huang, Meiai Li, Li Zhang, Ping Huang, Xiaoqiong Gu
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (3): BSR20180367.
Published: 22 May 2018
... become one of the most common pediatric cardiovascular diseases. Previous studies have reported that miR-218 rs11134527 A>G is associated with susceptibility to various cancer risks. However, there is a lack of evidence regarding the relationship between this polymorphism and KD risk. The present...
Articles
Qian Li, Wenying Zhu, Bei Zhang, Yiping Wu, Sen Yan, Yufeng Yuan, Haiyan Zhang, Jie Li, Kai Sun, Hua Wang, Tingting Yu
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (3): BSR20171381.
Published: 22 May 2018
... was significantly associated with CHD susceptibility in Chinese population, potentially via regulating MALAT1 expression. Correspondence: Hua Wang ( wanghuaksmed@yeah.net ) or Tingting Yu ( tingting@njmu.edu.cn ) * These authors contributed equally to this work. 18 10 2017 03 01 2018 10...
Includes: Supplementary data
Articles
Zhuorong Zhang, Yitian Chang, Wei Jia, Jiao Zhang, Ruizhong Zhang, Jinhong Zhu, Tianyou Yang, Huimin Xia, Yan Zou, Jing He
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (1): BSR20171667.
Published: 08 February 2018
... and mortality rates of its high-risk form. Previous genome-wide association studies (GWASs) identified the LINC00673 rs11655237 C>T polymorphism to be associated with the susceptibility of several malignant tumors. However, the association between this polymorphism and neuroblastoma susceptibility...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (1): BSR20170656.
Published: 02 February 2018
...Shao-Jun Ma; Yan-Mei Liu; Yue-Lang Zhang; Ming-Wei Chen; Wei Cao The aim of the present study was to investigate the correlation of enhancer of Zeste homolog 2 ( EZH2 ) and SET and MYND domain containing 3 ( SMYD3 ) gene polymorphisms with breast cancer susceptibility and prognosis. A total of 712...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (3): BSR20160644.
Published: 17 May 2017
...Kun Zeng; Bo Zhong; Min Fang; Xiao-Li Shen; Li-Na Huang The present case study aims to elucidate the correlation between the human 8-hydroxyguanineglycosylase ( hOGG1 ), APE1 and X-ray repair cross-complementing gene 1 ( XRCC1 ) gene polymorphisms to the susceptibility and clinicopathological...
