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Keywords: single nucleotide polymorphisms
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Articles
Biosci Rep (2022) 42 (6): BSR20220465.
Published: 27 June 2022
... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . colorectal cancer Prognosis PUNISHER rs12318065 single nucleotide polymorphisms survival Colon cancer (CC...
Articles
Biosci Rep (2021) 41 (10): BSR20211338.
Published: 19 October 2021
... access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . association study gestational diabetes mellitus retinoid X receptor single nucleotide polymorphisms susceptibility...
Articles
Biosci Rep (2021) 41 (7): BSR20210124.
Published: 26 July 2021
.... The purpose of the present study was to determine the association between four candidate single nucleotide polymorphisms (SNPs) in STAT4 genes and HCC risk in Chinese Han population. Methods: A case–control study was conducted to assess the association between STAT4 SNPs and HCC risk in 1011 Chinese Han...
Articles
Biosci Rep (2021) 41 (4): BSR20204136.
Published: 22 April 2021
...Danyang Wang; Qingmin Liu; Yanjun Ren; Yan Zhang; Xin Wang; Bing Liu Background: There is accumulating evidence of aberrant expression of miR-143 and miR-145 and their target gene KRAS in colorectal cancer (CRC). We hypothesize that single nucleotide polymorphisms (SNPs) within or near mRNA...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (1): BSR20202584.
Published: 14 January 2021
... levels. Allele-specific polymerase chain reaction blood donors ferritin hepcidin single nucleotide polymorphisms Numerous biologic processes rely upon adequate iron levels [ 1 ]. Over the past decade, many traits/disease-associated single-nucleotide polymorphisms (SNPs) have been reported...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (10): BSR20202628.
Published: 28 October 2020
... of CMIP single-nucleotide polymorphisms (SNPs) on dyslipidaemia and clinicopathologic features of IgAN. Clinical and pathological data from patients with IgAN diagnosed at the First Affiliated Hospital of Guangxi Medical University were collected. DNA was extracted from blood samples. CMIP rs2925979...
Articles
Biosci Rep (2020) 40 (9): BSR20202102.
Published: 24 September 2020
...Fei Bai; Ke Xiao Background: Gastric cancer (GC) is a complex multifactorial disease. Previous studies have revealed genetic variations associated with the risk of gastric cancer. The purpose of the present study was to determine the correlation between single-nucleotide polymorphisms (SNPs...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (8): BSR20193312.
Published: 28 August 2020
...Xu Chao; Xuesong Feng; Hailong Shi; Yuewen Wang; Lanlan Wang; Haiyu Shen; Qing Zha; Yanni Chen; Chao Jiang Numerous evidence has revealed that single-nucleotide polymorphisms (SNPs) are associated with liver cancer risk. To assess whether the MIR17HG polymorphisms are associated with the liver...
Articles
Biosci Rep (2020) 40 (8): BSR20202072.
Published: 17 August 2020
...Yu-Huei Liu; Chiou-Yuan Shen; Fuu-Jen Tsai The macrophage migration inhibitory factor (MIF)/cluster of differentiation 74 (CD74) plays a role in immunological functions. The present study aims to investigate whether single-nucleotide polymorphisms (SNPs) in the MIF and CD74 are risk factors...
Articles
Biosci Rep (2020) 40 (6): BSR20200824.
Published: 25 June 2020
..., IBM SPSS statistics 25 and Stata MP 16.0 software were used to do this meta-analysis. Results: Our meta-analysis involved 2553 PCOS patients and 3152 controls, for two single nucleotide polymorphisms (rs10830963 C> G in MTNR1B and rs2119882 T> C in MTNR1A) and significant associations were found...
Articles
Biosci Rep (2020) 40 (5): BSR20192320.
Published: 28 May 2020
... (CC BY) . tumour necrosis factors cancer single nucleotide polymorphisms meta analysis Increasing studies have demonstrated that a number of proinflammatory cytokines could be associated with the development of cancer [ 1 , 2 ]. Lymphotoxin-α (LTA) is the predominant member...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (2): BSR20194307.
Published: 28 February 2020
... Commons Attribution License 4.0 (CC BY) . heat shock proteins gene polymerase chain reaction preeclampsia single nucleotide polymorphisms Pre-eclampsia (PE) is a pregnancy-specific syndrome characterized by de novo hypertension (systolic blood pressure higher than 140 mmHg...
Articles
Biosci Rep (2019) 39 (12): BSR20191301.
Published: 20 December 2019
... Commons Attribution License 4.0 (CC BY) . -238G/A -308G/A meta analysis single nucleotide polymorphisms T2DM TNF-α Diabetes is a global epidemic, with an estimated worldwide prevalence of 1 in 11 adults (approximately 425 million people in 2017), and is projected to increase to 629...
Articles
Biosci Rep (2019) 39 (8): BSR20190299.
Published: 07 August 2019
...) with atherosclerotic, cardiovascular disease. So far, a link between common genetic variations of the SGLT2 encoding gene SLC5A2 and glucose homeostasis as well as cardiovascular disease has not been established. The present study, therefore, aimed to investigate SLC5A2 single nucleotide polymorphisms (SNPs...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (7): BSR20191155.
Published: 19 July 2019
... of these two genes and the risk of cervical cancer in the Uygur women. The study involved 342 cervical cancer patients and 498 healthy women. Five single nucleotide polymorphisms (SNPs) from the TNFAIP8L1 gene and the FLT1 gene were selected and genotyped. Odds ratio and 95% CIs were calculated by logistic...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (6): BSR20190783.
Published: 20 June 2019
... the Creative Commons Attribution License 4.0 (CC BY) . HBV HCC Meta-analysis single nucleotide polymorphisms STAT3 STAT4 Hepatitis B virus (HBV) is one of the most important human viral pathogens which causes a wide range of acute and chronic liver diseases [ 1 ]. Globally, more than 257...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (5): BSR20190024.
Published: 14 May 2019
... dose, applied duration, and single-nucleotide polymorphism (SNP). We also conducted a dose-response meta-analysis to analyze the cumulative dosage and SONFH risk in mutation carriers. There were significant correlations between the ABCB1 rs1045642 mutant and SONFH in the prednisone-use...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (5): BSR20181400.
Published: 07 May 2019
...Haichuan Wang; Hui Cao; Zhong Xu; Dong Wang; Yong Zeng The association of major histocompatibility complex class I chain-related gene A ( MICA ) single nucleotide polymorphism (SNP) rs2596542G>A and hepatocellular carcinoma (HCC) has been broadly studied, with inconsistent results. Therefore, we...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (4): BSR20180723.
Published: 16 April 2019
... in microRNAs (miRNAs/miRs) play an important role in the susceptibility of various types of cancers. Objective: To evaluate the association of Single Nucleotide Polymorphisms (SNPs) in miR-146a (rs2910164), miR-196a2 (rs11614913), and miR-499 (rs3746444), with cervical cancer susceptibility in Indian...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (4): BSR20190091.
Published: 16 April 2019
... with growth inhibition [ 11 ]. In recent years, studies have shown that GAS5 plays a significant role in the development of tumors including breast cancer [ 12 ], cervical cancer [ 13 ], prostate cancer [ 14 ] etc. Single nucleotide polymorphism (SNP) is the DNA sequence polymorphism caused by single...
Articles
Biosci Rep (2019) 39 (3): BSR20182104.
Published: 01 March 2019
... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . ADIPOQ knee osteoarthritis single nucleotide polymorphisms Osteoarthritis (OA) is a clinical syndrome of joint pain and dysfunction that attacks millions...
Articles
Biosci Rep (2019) 39 (1): BSR20182228.
Published: 25 January 2019
... 01 2019 07 01 2019 © 2019 The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . MGP Osteoarthritis Polymorphism single nucleotide...
Articles
Biosci Rep (2019) 39 (1): BSR20180789.
Published: 18 January 2019
... effect. The discovery of GAS5 and in-depth study of single nucleotide polymorphism (SNP) mechanism can provide a new way for the prevention and treatment of digestive system tumors. Correspondence: Sheng Tai ( taisheng1973@163.com ) or Xingming Jiang ( xmjiang@hrbmu.edu.cn ) 20 05 2018 16...
Articles
Biosci Rep (2019) 39 (1): BSR20181770.
Published: 15 January 2019
... methionine synthase meta analysis single nucleotide polymorphisms susceptibility Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, which accounts for 30% of all malignancy diagnosed in children and 80% of pediatric leukemia [ 1 ]. However, the etiology and biological...
Articles
Biosci Rep (2018) 38 (6): BSR20181619.
Published: 30 November 2018
... the association of other single nucleotide polymorphisms and musculoskeletal degenerative diseases. Correspondence : Fei Gao ( gaofei13935110660@hotmail.com ) 13 09 2018 15 10 2018 23 10 2018 28 10 2018 © 2018 The Author(s). 2018 This is an open access article published...
Articles
Biosci Rep (2018) 38 (5): BSR20180658.
Published: 05 September 2018
... the Creative Commons Attribution License 4.0 (CC BY) . cancer High mobility group box 1 meta analysis single nucleotide polymorphisms High mobility group box 1 (HMGB1), also known as HMG1 [ 1 ], is a highly conserved, ubiquitously expressed single polypeptide in all mammalian eukaryotic cells...
Articles
Biosci Rep (2018) 38 (3): BSR20180072.
Published: 27 June 2018
...Jing Wen; Zhi Lv; Hanxi Ding; Xinxin Fang; Mingjun Sun Single nucleotide polymorphisms (SNPs) in miRNA biosynthesis genes DROSHA and DGCR8 were indicated to be correlated with cancer risk. We comprehensively reviewed and analyzed the effect of DROSHA and DGCR8 polymorphisms on cancer risk. Eligible...
Includes: Supplementary data
Articles
Biosci Rep (2018) 38 (3): BSR20171565.
Published: 31 May 2018
..., and their genetic variants are involved in the development of various cancers. Our study aimed to determine the potential association between miRNA processing gene polymorphisms and cervical precancerous lesions. Five single nucleotide polymorphisms (SNPs), including Ran-GTP ( RAN ) rs14035, exportin-5 ( XPO5...
Includes: Supplementary data
Articles
Biosci Rep (2017) 37 (2): BSR20170145.
Published: 28 April 2017
...Xin-Man Dou; Hui-Juan Cheng; Ling Meng; Lin-Lin Zhou; Yi-Hong Ke; Li-Ping Liu; Yu-Min Li The aim of the present study is to investigate association between septic shock (SS) and angiotensin I-converting enzyme ( ACE ) single nucleotide polymorphisms (SNPs). From October 2009 to December 2016, 238...