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Keywords: single nucleotide polymorphisms
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Biosci Rep (2021) 41 (4): BSR20204136.
Published: 22 April 2021
...Danyang Wang; Qingmin Liu; Yanjun Ren; Yan Zhang; Xin Wang; Bing Liu Background: There is accumulating evidence of aberrant expression of miR-143 and miR-145 and their target gene KRAS in colorectal cancer (CRC). We hypothesize that single nucleotide polymorphisms (SNPs) within or near mRNA...
Includes: Supplementary data
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Biosci Rep (2020) 40 (10): BSR20202628.
Published: 28 October 2020
... of CMIP single-nucleotide polymorphisms (SNPs) on dyslipidaemia and clinicopathologic features of IgAN. Clinical and pathological data from patients with IgAN diagnosed at the First Affiliated Hospital of Guangxi Medical University were collected. DNA was extracted from blood samples. CMIP rs2925979...
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Biosci Rep (2020) 40 (9): BSR20202102.
Published: 24 September 2020
...Fei Bai; Ke Xiao Background: Gastric cancer (GC) is a complex multifactorial disease. Previous studies have revealed genetic variations associated with the risk of gastric cancer. The purpose of the present study was to determine the correlation between single-nucleotide polymorphisms (SNPs...
Includes: Supplementary data
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Biosci Rep (2020) 40 (8): BSR20193312.
Published: 28 August 2020
...Xu Chao; Xuesong Feng; Hailong Shi; Yuewen Wang; Lanlan Wang; Haiyu Shen; Qing Zha; Yanni Chen; Chao Jiang Numerous evidence has revealed that single-nucleotide polymorphisms (SNPs) are associated with liver cancer risk. To assess whether the MIR17HG polymorphisms are associated with the liver...
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Biosci Rep (2020) 40 (8): BSR20202072.
Published: 17 August 2020
...Yu-Huei Liu; Chiou-Yuan Shen; Fuu-Jen Tsai The macrophage migration inhibitory factor (MIF)/cluster of differentiation 74 (CD74) plays a role in immunological functions. The present study aims to investigate whether single-nucleotide polymorphisms (SNPs) in the MIF and CD74 are risk factors...
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Biosci Rep (2020) 40 (6): BSR20200824.
Published: 25 June 2020
..., IBM SPSS statistics 25 and Stata MP 16.0 software were used to do this meta-analysis. Results: Our meta-analysis involved 2553 PCOS patients and 3152 controls, for two single nucleotide polymorphisms (rs10830963 C> G in MTNR1B and rs2119882 T> C in MTNR1A) and significant associations were found...
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Biosci Rep (2020) 40 (5): BSR20192320.
Published: 28 May 2020
... polymorphism is inversely associated with the risk of cancer. LTA rs1041981 polymorphism is negatively associated with cancer risk in Asia. While, LTA rs909253 polymorphism is a risk factor for HCC in Caucasian population. tumour necrosis factors cancer single nucleotide polymorphisms meta analysis...
Includes: Supplementary data
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Biosci Rep (2020) 40 (2): BSR20194307.
Published: 28 February 2020
... BY) . heat shock proteins gene polymerase chain reaction preeclampsia single nucleotide polymorphisms Pre-eclampsia (PE) is a pregnancy-specific syndrome characterized by de novo hypertension (systolic blood pressure higher than 140 mmHg and/or diastolic blood pressure higher than 90 mmHg...
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Biosci Rep (2019) 39 (12): BSR20191301.
Published: 20 December 2019
... Commons Attribution License 4.0 (CC BY) . -238G/A -308G/A meta analysis single nucleotide polymorphisms T2DM TNF-α This meta-analysis was conducted according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis 2009 (PRISMA2009). All...
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Biosci Rep (2019) 39 (8): BSR20190299.
Published: 07 August 2019
...) with atherosclerotic, cardiovascular disease. So far, a link between common genetic variations of the SGLT2 encoding gene SLC5A2 and glucose homeostasis as well as cardiovascular disease has not been established. The present study, therefore, aimed to investigate SLC5A2 single nucleotide polymorphisms (SNPs...
Includes: Supplementary data
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Biosci Rep (2019) 39 (7): BSR20191155.
Published: 19 July 2019
... of these two genes and the risk of cervical cancer in the Uygur women. The study involved 342 cervical cancer patients and 498 healthy women. Five single nucleotide polymorphisms (SNPs) from the TNFAIP8L1 gene and the FLT1 gene were selected and genotyped. Odds ratio and 95% CIs were calculated by logistic...
Includes: Supplementary data
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Biosci Rep (2019) 39 (5): BSR20190024.
Published: 14 May 2019
... dose, applied duration, and single-nucleotide polymorphism (SNP). We also conducted a dose-response meta-analysis to analyze the cumulative dosage and SONFH risk in mutation carriers. There were significant correlations between the ABCB1 rs1045642 mutant and SONFH in the prednisone-use...
Includes: Supplementary data
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Biosci Rep (2019) 39 (5): BSR20181400.
Published: 07 May 2019
...Haichuan Wang; Hui Cao; Zhong Xu; Dong Wang; Yong Zeng The association of major histocompatibility complex class I chain-related gene A ( MICA ) single nucleotide polymorphism (SNP) rs2596542G>A and hepatocellular carcinoma (HCC) has been broadly studied, with inconsistent results. Therefore, we...
Includes: Supplementary data
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Articles
Biosci Rep (2019) 39 (4): BSR20190091.
Published: 16 April 2019
... with growth inhibition [ 11 ]. In recent years, studies have shown that GAS5 plays a significant role in the development of tumors including breast cancer [ 12 ], cervical cancer [ 13 ], prostate cancer [ 14 ] etc. Single nucleotide polymorphism (SNP) is the DNA sequence polymorphism caused by single...
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Biosci Rep (2019) 39 (3): BSR20182104.
Published: 01 March 2019
... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . ADIPOQ knee osteoarthritis single nucleotide polymorphisms Osteoarthritis (OA) is a clinical syndrome of joint pain and dysfunction that attacks millions...
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Biosci Rep (2019) 39 (1): BSR20182228.
Published: 25 January 2019
... 01 2019 07 01 2019 © 2019 The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . MGP Osteoarthritis Polymorphism single nucleotide...
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Biosci Rep (2019) 39 (1): BSR20180789.
Published: 18 January 2019
... effect. The discovery of GAS5 and in-depth study of single nucleotide polymorphism (SNP) mechanism can provide a new way for the prevention and treatment of digestive system tumors. Correspondence: Sheng Tai ( taisheng1973@163.com ) or Xingming Jiang ( xmjiang@hrbmu.edu.cn ) 20 05 2018 16...
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Biosci Rep (2019) 39 (1): BSR20181770.
Published: 15 January 2019
... methionine synthase meta analysis single nucleotide polymorphisms susceptibility Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, which accounts for 30% of all malignancy diagnosed in children and 80% of pediatric leukemia [ 1 ]. However, the etiology and biological...
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Biosci Rep (2018) 38 (5): BSR20180658.
Published: 05 September 2018
... the Creative Commons Attribution License 4.0 (CC BY) . cancer High mobility group box 1 meta analysis single nucleotide polymorphisms High mobility group box 1 (HMGB1), also known as HMG1 [ 1 ], is a highly conserved, ubiquitously expressed single polypeptide in all mammalian eukaryotic cells...
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Biosci Rep (2018) 38 (3): BSR20180072.
Published: 27 June 2018
...Jing Wen; Zhi Lv; Hanxi Ding; Xinxin Fang; Mingjun Sun Single nucleotide polymorphisms (SNPs) in miRNA biosynthesis genes DROSHA and DGCR8 were indicated to be correlated with cancer risk. We comprehensively reviewed and analyzed the effect of DROSHA and DGCR8 polymorphisms on cancer risk. Eligible...
Includes: Supplementary data
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Biosci Rep (2018) 38 (3): BSR20171565.
Published: 31 May 2018
..., and their genetic variants are involved in the development of various cancers. Our study aimed to determine the potential association between miRNA processing gene polymorphisms and cervical precancerous lesions. Five single nucleotide polymorphisms (SNPs), including Ran-GTP ( RAN ) rs14035, exportin-5 ( XPO5...
Includes: Supplementary data
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