... study was to develop and validate a prognostic IRlncRNA signature for CRC patients. Methods: Gene expression profiles of CRC samples were downloaded from The Cancer Genome Atlas (TCGA) database. Immune-related genes were obtained from the ImmPort database and were used to identify IRlncRNA...

...-risk groups based on the median risk score. The predictive ability of the risk signature was estimated through bioinformatics analyses. Results: Six ADME-related genes ( CYP2C9, ABCB6, ABCC5, ADH4, DHRS13 , and SLCO2A1 ) were used to construct the prediction model with a good predictive ability...

... Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . head and neck squamous cell carcinoma lncRNA mRNA signature survival Worldwide, head and neck squamous cell carcinoma (HNSCC) is one of the most lethal cancers. It was estimated that 108700 new cases...

... of the prognostic value of lncRNAs in head and neck squamous cell carcinoma (HNSCC) is in infancy. In the present study, we analyzed the lncRNA expression data in a large number of HNSCC patients ( n =425) derived from The Cancer Genome Atlas (TCGA) to identify an lncRNA expression signature for improving...