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Keywords: proteomics
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Biosci Rep (2023) 43 (5): BSR20230067.
Published: 18 May 2023
... . In addition, quantitative proteomics and bioinformatics analysis confirmed that PPT1 acts by affecting the metabolism, localization, and function of various macromolecular proteins. The present study reveals that PPT1 could be a promising therapeutic target for the treatment of HCC. These findings provided...
Includes: Supplementary data
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Biosci Rep (2021) 41 (8): BSR20211532.
Published: 20 August 2021
... are discovered for in-depth research and characterization of the precise and dynamic regulation of ubiquitylomics in multiple cellular processes during cancer initiation, progression and treatment. In the present study, 4D label-free quantitative techniques of ubiquitination proteomics were used and we...
Includes: Supplementary data
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Biosci Rep (2021) 41 (6): BSR20210344.
Published: 04 June 2021
... Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . acute coronary syndrome biomarkers pathogenesis proteomics Acute coronary syndrome (ACS) refers to the clinical symptoms of ischemia or restricted blood supply from...
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Biosci Rep (2021) 41 (1): BSR20202219.
Published: 19 January 2021
..., proteomic analysis was used to identify the differentially expressed proteins (DEPs) and then evaluate the potential plasma biomarkers between CMS and non-CMS groups. A total of 145 DEPs were detected in CMS Han Chinese people who live in the plateau (CMS-HPu), among which 89 were significantly up-regulated...
Includes: Supplementary data
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Biosci Rep (2020) 40 (5): BSR20191517.
Published: 07 May 2020
...Yanan Xu; Xian Li; Duriwa Man; Xiulan Su; Gula A Objective: To explore the proteomic changes in the hypothalamus of rats treated with Mongolian medical warm acupuncture for insomnia therapy based proteomics. Method: We used an iTRAQ-based quantitative proteomic approach to identify proteins...
Includes: Supplementary data
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Biosci Rep (2017) 37 (3): BSR20170042.
Published: 21 June 2017
... in lung tissues of COPD rats. We also investigated therapeutic effects of aminophylline (APL) on the COPD rats and integrated transcriptome, proteome, and metabolome data for a global view of molecular mechanisms of COPD progression. Using molecular function and pathway analyses, the genes and proteins...
Includes: Supplementary data
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Biosci Rep (2016) 36 (1): e00302.
Published: 29 February 2016
... increased binding to monomeric G-actin, profilin 2 and the F-actin capping protein, CapZ α-1. actin cytoskeleton FSGS podocytes proteomics Figure 5 Quantification of the interaction between profillin 2 and the F-actin capping protein with wild type and disease causing mutations of INF2...
Includes: Supplementary data
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Biosci Rep (2010) 30 (3): 209–215.
Published: 03 March 2010
...Hui-peng Yao; Lin Chen; Xingwei Xiang; Ai-qin Guo; Xing-meng Lu; Xiao-feng Wu A cell line is an important experimental platform for biological sciences as it can basically reflect the biology of its original organism. In this study, we firstly characterized the proteome of cultured BmN cells...
Includes: Supplementary data
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Biosci Rep (2005) 25 (1-2): 71–93.
Published: 04 February 2005
...Ida Chiara Guerrera; Oliver Kleiner Mass spectrometry has arguably become the core technology in proteomics. The application of mass spectrometry based techniques for the qualitative and quantitative analysis of global proteome samples derived from complex mixtures has had a big impact...
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Biosci Rep (2005) 25 (1-2): 95–106.
Published: 04 February 2005
...Andreas Kremer; Reinhard Schneider; Georg C. Terstappen The field of proteomics is advancing rapidly as a result of powerful new technologies and proteomics experiments yield a vast and increasing amount of information. Data regarding protein occurrence, abundance, identity, sequence, structure...
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Biosci Rep (2002) 22 (1): 81–98.
Published: 01 February 2002
... effects of mitochondrial tRNA mutations on a broader global mitochondrial level will also be presented. Initial results obtained by comparative mitochondrial proteomics turn out to be very promising for deciphering unexpected molecular partners involved in the pathological status of the mitochondria. ©...