... indicator as to whether an enzyme is psychrophilic or not and that models of psychrophilic enzyme catalysis need to account for this gap. Additionally, by using predictive protein stability software, HoTMuSiC and PoPMuSiC, we show that the deleterious nature of amino acid substitutions to protein stability...

.... However, the bottlenecks in this labelling reaction is requirement of high protein concentration, maintenance of protein stability during the labelling process as well as high background fluorescence due to ineffective removal of unreacted FITC, prior to fluorescence studies. Therefore, to overcome...

... BY) . gene expression and regulation protein stability plant hromones post translational modification Plants are sessile organisms and their growth and development are controlled by multiple environmental cues and endogenous hormones. Light, the energy source for plant photosynthesis, is also one...

... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . lung tissue protein stability RBFOX3 tight junctions ubiquitin-proteasomal degradation RNA-binding proteins play important roles in regulation of gene expression by affecting mRNA stability...

... (ATP)-independent chaperone disulfide bond protein stability protein–protein interaction small Tim protein Translocase of IM (inner membrane; Tim)9 and Tim10 are essential members of the ‘small Tim’ (also known as ‘Tiny Tim’) protein family of the mitochondrial intermembrane space (IMS...

.... EphB1 EphB2 EphB3 EphB4 kinase inhibition protein stability Kinetic assays were based on in vitro phosphorylation of a generic tyrosine kinase substrate poly-(Glu:Tyr) (4:1, 20000–50000 Da; Sigma) in a stopped reaction format, using the ADP-Glo™ luminescent kinase assay kit (Promega...

.... The G202A, R346W DHODH proteins showed reduced protein stability. On the other hand, the third one R135C, in which the mutation lies at the ubiquinone-binding site, was stable but possessed no enzymatic activity. In conclusion, the G202A and R346W mutation causes deficient protein stability, and the R135C...