...Zhili Zeng; Zebiao Cao; Enxin Zhang; Haifu Huang; Ying Tang Background: Hepatocellular carcinoma (HCC) is a malignant tumor with rapid progression, high recurrence rate and poor prognosis. The objective of our investigation was to explore the prognostic value of CDK5R1 in HCC. Methods: The raw data...

... investigated the expression level, prognostic value, and potential function of PPPs with data from Oncomine, GEPIA, THPA, and TCGA databases and an independent cohort of patients with pancreatic cancer. Among all the PPP catalytic subunits (PPPcs), the transcription levels of PPP1CA, PPP1CB, PPP3CA, PPP3CB...

... Immunotherapy Ovarian cancer Prognostic value Tumor-infiltrating immune cells Ovarian cancer (OvCa) is the fifth leading cause of cancer-related deaths in women with 295,414 new cases and 184,799 estimated deaths in 2018 [ 1 , 2 ]. Given that the ovaries are located in the pelvic cavity, the early...

... and CD200R, in different subtypes of breast cancer and assessed their prognostic value. The results showed that the expression patterns of these 50 immune checkpoint genes were distinct in breast cancer. High expression of B7-H3 mRNA was significantly associated with worse overall survival (OS), especially...

..., apoptosis, angiogenesis, invasion, and metastasis. Dysregulation of F-box proteins may lead to an unbalanced proteolysis of numerous protein substrates, contributing to progression of human malignancies. However, the prognostic values of F-box members, especially at mRNA levels, in breast cancer (BC...