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Keywords: podocytes
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Biosci Rep (2016) 36 (1): e00302.
Published: 29 February 2016
... that three mutations associated with FSGS, E184K, S186P and R218Q, reduce INF2 auto-inhibition and increase association with monomeric actin. Furthermore using a combination of GFP–INF2 expression in human podocytes and GFP-Trap purification coupled with MS we demonstrate that INF2 interacts with profilin 2...
Includes: Supplementary data