... © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . NUF2 pancreatic cancer RNA interference treatment This Retraction...

... and mechanisms of ASCT2 in pancreatic cancer (PC) are largely unknown. Our results show that ASCT2 expression is significantly higher in PC than in normal pancreatic duct cells and pancreas. Utilizing the Kaplan–Meier Plotter database, a high expression of SLC1A5 mRNA was significantly associated with poor...

...Bo Liu; Tingting Fu; Ping He; Chengyou Du; Ke Xu Purpose: To identify differentially expressed immune-related genes (DEIRGs) and construct a model with survival-related DEIRGs for evaluating the prognosis of patients with pancreatic cancer (PC). Methods: Six microarray gene expression datasets...

... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . NUF2 pancreatic cancer RNA interface tumourigenesis treatment...

... of m1A regulators in pancreatic cancer. In the present study, data on gene mutations, single-nucleotide variants (SNVs), and copy number variation (CNV) were obtained from 363 patients with pancreatic cancer in the Cancer Genome Atlas (TCGA) database, and survival analysis was performed using...

...Junjie Hang; Steven Yuk-Fai Lau; Ruohan Yin; Lina Zhu; Siyuan Zhou; Xin Yuan; Lixia Wu Compelling evidence suggests that phosphoprotein phosphatases (PPPs) are involved in a large spectrum of physiological and pathological processes, but little is known about their roles in pancreatic cancer. We...

... pancreatic cancer T cell receptor signaling pathway TGF-β As one of the most aggressive malignancies, pancreatic cancer (PC) causes 4.5% of all cancer-related deaths worldwide in 2015 [ 1 ]. PC is widely recognized as a ‘cold’ tumor due to its notable immunosuppression [ 2 ]; thus, enhancing...

... was considered to be statistically significant in all the analyses. Neutrophil-lymphocyte ratio pancreatic cancer prognosis Pancreatic ductal adenocarcinoma (PDAC), one of the most common cancers with high degree of malignancy, is a devastating disease all over the world [ 1–3 ]. Although...

...Xin Sui; Zhenghui Sui As one of the most prevalent malignant tumors, pancreatic cancer (PC) is a leading fatal cancer worldwide. Surging evidence has unraveled that miRNAs are involved in the occurrence and progression of multiple cancers, including PC. The tumor suppressor effects of miR-4269 have...

...Wei Cao; Guoxiong Zhou Pancreatic cancer is a kind of malignant carcinoma with high mortality, which is devoid of early diagnostic biomarker and effective therapeutic methods. Recently, long non-coding RNAs (lncRNAs) have been reported as a crucial role in regulating the development of various...

...Fahong Wu; Yanling Chen; Jinhai Zhu Pancreatic cancer (PaCa) is a common malignant tumor of the digestive system with poor prognosis and no ideal treatment for inoperable patients, which is partly due to delayed diagnoses. It is recently reported that the protein histidine phosphatase LHPP...

...Liguo Hao; Lijie Liu; Xin Meng; Guanghao Yu; Enbang Li; Hongqian Gu Pancreatic cancer is a common malignant tumor with high incidence of metastasis. Currently, there is no absolute standard for the choice of b-value for diffusion-weighted imaging (DWI) for pancreatic cancer. The b-value is rarely...

...Jianmin Sun; Yubao Zhang The level of expression of long non-coding RNA (LncRNA) X-inactive specific transcript (XIST) is up-regulated in pancreatic cancer (PC). However, the role of XIST in PC and the underlying mechanism are still unknown. The present study aimed to elucidate how XIST...

...Peng Chen; Meiying Wang; Cuiping Wang To investigate the possible mechanism of Qingyihuaji formula (QYHJ) for reversing gemcitabine (GEM) resistant human pancreatic cancer. Cell proliferation, apoptosis, migration and invasion were detected in CFPAC-1 cells. Xenograft mice established with CFPAC-1...

...Huimin Lu; Shan Lu; Dujiang Yang; Ling Zhang; Jun Ye; Mao Li; Weiming Hu Ribonucleotide reductase subunit M2 ( RRM2 ) acts as an important gemcitabine resistance-related gene in pancreatic cancer (PC). Here, we aimed to investigate the potential microRNA that regulates gemcitabine chemosensitivity...

...Xian-Ping Cui; Chuan-Xi Wang; Zhi-Yi Wang; Jian Li; Ya-Wen Tan; Song-Tao Gu; Cheng-Kun Qin LncRNA TP73 antisense RNA 1T (TP73-AS1) plays an important role in human malignancies. However, the levels of TP73-AS1 and its functional mechanisms in pancreatic cancer metastasis remain unknown...

...Li Li; Xuesong Gai Previous reports have suggested a potential association on dietary zinc intake with the risk of pancreatic cancer. Since the associations between different studies were controversial, we therefore conducted a meta-analysis to reassess the relationship between dietary zinc intake...

...Tao Zhang; Hongqiang Chen; Shiyong Qin; Minghai Wang; Xianming Wang; Xin Zhang; Fei Liu; Shuguang Zhang Whether dietary vitamin A intake could reduce pancreatic cancer risk is still conflicting. We therefore conducted a meta-analysis to summarize the evidence from epidemiological studies. We...

...Lei Wang; Jianfeng Wang; Xudong Liu; Qian Liu; Guozhuan Zhang; Lishuang Liang Quantification of the association between the intake of selenium and risk of pancreatic cancer is still conflicting. Thus, we conducted a meta-analysis to summarize the evidence from epidemiological studies of selenium...

...Peng Hu; Xi Chen; Jing Sun; Ping Bie; Lei-Da Zhang NUF2 (NUF2, Ndc80 kinetochore complex component) plays an important role in kinetochore-microtubule attachment. It has been reported that NUF2 is associated with multiple human cancers. However, the functional role of NUF2 in pancreatic cancer...

...Margherita Gaviraghi; Patrizia Tunici; Silvia Valensin; Marco Rossi; Cinzia Giordano; Letizia Magnoni; Mario Dandrea; Licia Montagna; Rossana Ritelli; Aldo Scarpa; Annette Bakker Pancreatic cancer stem-like cells are described by membrane expression of CD24, CD44 and ESA (epithelial-specific...