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Keywords: p-AKT
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Down-regulating GRP78 reverses pirarubicin resistance of triple negative breast cancer by miR-495-3p mimics and involves the p-AKT/mTOR pathway

Mian Liu, Jiu Yang, Wuwu Lv, Shuanglian Wang, Tao Du, Kejing Zhang, Yuhui Wu, Xueping Feng
Journal: Bioscience Reports
Biosci Rep (2022) 42 (1): BSR20210245.
https://doi.org/10.1042/BSR20210245
Published: 06 January 2022
...-3p mimics also inhibited cell proliferation and migration. Based on our results, miR-495-3p mimics could down-regulate GRP78 expression via the p-AKT/mTOR signaling pathway in TNBC cells. Remarkably, chemo-resistant and chemo-sensitive TNBC tissues had opposite trends in GRP78 and miR-495-3p...
View article titled, Down-regulating GRP78 reverses pirarubicin resistance of triple negative breast cancer by miR-495-3p mimics and involves the <span class="search-highlight">p</span>-<span class="search-highlight">AKT</span>&#x2F;mTOR pathway
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Includes: Supplementary data