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Keywords: multiple myeloma
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Biosci Rep (2022) 42 (2): BSR20212721.
Published: 11 February 2022
... and immunoproteasome inhibitor, capable of inducing cell death in multiple myeloma, triple-negative breast cancer, (TNBC) and non-small cell lung cancer lines. TIR-199 also effectively inhibits the proteasome in primary myeloma cells of patients, and bypasses the PSMB5 A49T+A50V bortezomib-resistant mutant. TIR-199...
Includes: Supplementary data
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Biosci Rep (2015) 35 (6): e00274.
Published: 08 December 2015
...Kévin Adam; Mireille Lambert; Elsa Lestang; Gabriel Champenois; Isabelle Dusanter-Fourt; Jérôme Tamburini; Didier Bouscary; Catherine Lacombe; Yael Zermati; Patrick Mayeux The oncogenic Pim2 kinase is overexpressed in several haematological malignancies, such as multiple myeloma and acute myeloid...
Includes: Supplementary data