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Keywords: mitochondrial apoptotic pathways
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Biosci Rep (2019) 39 (1): BSR20181802.
Published: 15 January 2019
... remarkably suppressed the tumor growth in nude mice via induction of apoptosis at 0.05 and 0.1 mg/kg. In addition, no visible toxicity was observed in liver and renal tissue of mice. This finding suggests that Colchicine-induced apoptosis is associated with caspase-3-mediated mitochondrial apoptotic pathways...