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Keywords: microRNA
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Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (7): BSR20212355.
Published: 15 July 2022
... under the Creative Commons Attribution License 4.0 (CC BY) . atherosclerosis endothelial cells microRNA non-coding RNA vascular smooth muscle Correspondence: Eoin Brennan ( eoin.brennan@ucd.ie ) 07 02 2022 17 05 2022 26 06 2022 27 06 2022 miR-126 (miR...
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (1): BSR20211972.
Published: 11 January 2022
... a clear clinical need for novel molecular markers that may overcome some of these limitations [ 9 ]. MicroRNAs (miRNAs) are a class of non-coding molecules which have emerged as strong candidates for useful clinical biomarkers [ 10 ]. Over the past decade, they have been actively researched in a wide...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (12): BSR20211420.
Published: 08 December 2021
... of the present study was to apply bioinformatics analysis to explore tumor-educated platelet (TEP) microRNA (miRNA) expression and its potential diagnostic utility in HCC. Methods: Twenty-five HCC patients and 25 healthy controls were included. RNA sequencing was utilized to screen miRNA alterations in platelets...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (10): BSR20211123.
Published: 19 October 2021
...Ying Jing; Donghai Li MicroRNAs (miRNAs) play important roles in a variety of human diseases, including breast cancer. A number of miRNAs are up- and down-regulated in breast cancer. However, little is known about miRNA similarity and similarity network in breast cancer. Here, a collection of 272...
Includes: Supplementary data
Articles
Nahla O. Mousa, Ahmed A. Sayed, Nagia Fahmy, Mariam G. Elzayat, Usama Bakry, Ahmed Abdellatif, Waheed K. Zahra, Ahmed Osman
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (9): BSR20211325.
Published: 17 September 2021
... study, we sequenced the whole miRNome in leukocytes and plasma of the family members and results were validated using real-time PCR. Our results highlighted the role of miR-409-3p, miR-424-5p, miR-144-3p as microRNAs that show correlation with the extent of severity of muscular weakness and can be used...
Includes: Supplementary data
Articles
Isabel Witvrouwen, Dominique Mannaerts, Jessica Ratajczak, Evi Boeren, Ellen Faes, Amaryllis H. Van Craenenbroeck, Yves Jacquemyn, Emeline M. Van Craenenbroeck
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (8): BSR20210874.
Published: 12 August 2021
... endothelial growth factor (VEGF) pathway is essential in the placentation process and VEGF expression is regulated through post-transcriptional modification by microRNAs (miRNAs). We investigated the expression of VEGF-related circulating miR-16, miR-29b, miR-126, miR-155 and miR-200c in PE vs healthy...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20210126.
Published: 01 July 2021
... the function of endothelial cells by dictating their microRNA (miRNA) expression remains largely unknown. Differentially expressed miRNAs (DEMs) were identified through dataset downloaded from the Gene Expression Omnibus (GEO) database and analyzed by GEO2R. We then used online tools to obtain potential...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (2): BSR20201158.
Published: 17 February 2021
...Hao Qiu; Zhiqiang Xie; Weifeng Tang; Chao Liu; Yafeng Wang; Haiyong Gu; Qingfeng Zheng MicroRNA ( miR ) acts as a negative regulator of gene expression. Many literatures have suggested that miRs may be involved in the process of cell proliferation, inflammation, oxidative stress, energy metabolism...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203559.
Published: 07 January 2021
...Mengqiu Xiong; Ping Wang; Bei Pan; Junjie Nie; Shukui Wang; Bangshun He MicroRNA-196a (miR-196a) was previously reported to be up-regulated in cancers, and it has the diagnostic and prognostic values in cancers. Whereas, the conclusion was still unclear according to the published data. To assess...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (11): BSR20201820.
Published: 17 November 2020
...Bo Ma; Hui Li; Jia Qiao; Tao Meng; Riyue Yu Background: Head and neck squamous cell carcinoma (HNSCC) is recognised as an immune active cancer, but little is known about the role of microRNAs (miRNAs) in it. In the present study, we aim to determine a prognostic and immune-related miRNAs signature...
Includes: Supplementary data
Articles
Hung-Ju Lin, Sung-Liang Yu, Ta-Chen Su, Hsiu-Ching Hsu, Ming-Fong Chen, Yuan-Teh Lee, Kuo-Liong Chien, Tzu-Pin Lu
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20201885.
Published: 21 September 2020
... be a biomarker suboptimal to assess inflammation status. Although it has been reported that statins modulated inflammation via microRNAs (miRNAs), evidence remains lacking on comprehensive profiling of statin-induced miRNAome alterations in immune cells. We recruited 19 hypercholesterolemic patients receiving 2...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20193974.
Published: 18 September 2020
...Peng Lv; Zhenzhu Zhang; Li Hou; Yayue Zhang; Lingeng Lu; Chong Wang; Fengqin Shi Low expression of tumor suppressor microRNA (miRNA) and high expression of carcinogenic miRNA promote the occurrence and progression of human cancer. Most studies show that miR-145 is a tumor suppressor miRNA...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20191028.
Published: 07 May 2020
...Daniel Lee; Wei Tang; Tiffany H. Dorsey; Stefan Ambs BACKGROUND: microRNAs (miRs) regulate the expression of protein-coding genes and play key roles in various biological processes, including development and immunity. However, dysregulation of miR expression is also involved in disease biology...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20182458.
Published: 21 April 2020
...Tingting Jia; Yipeng Ren; Fengze Wang; Rui Zhao; Bo Qiao; Lejun Xing; Long Ou; Bin Guo Objective: The current study aimed to investigate the functional roles and clinical significance of microRNA-148a ( miR-148a ) in the progression of oral squamous cell carcinoma (OSCC). Methods: Relative...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (1): BSR20190303.
Published: 17 January 2020
...Ying Xin; Xueqiang Wang; Kexin Meng; Chao Ni; Zhenye Lv; Dandan Guan Accumulated evidence has demonstrated exosomes of cancer cells carry microRNAs (miRNAs) to non-malignant cells to induce metastasis. The present study aimed to identify crucial exosomal miRNAs for breast cancer (BC) using...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (1): BSR20191234.
Published: 10 January 2020
...Derong Huang; Zhongxiu Chen; Jie Wang; Yucheng Chen; Daxing Liu; Ke Lin Aim: Circulating microRNA expression has become a biomarker of cardiovascular disease; however, the association of microRNA expression between circulation and myocardium in hypertrophic cardiomyopathy remains unclear...
Includes: Supplementary data
Articles
George S. Krasnov, Grigory A. Puzanov, Marina A. Afanasyeva, Erdem B. Dashinimaev, Khava S. Vishnyakova, Artemy D. Beniaminov, Alexei A. Adzhubei, Tatiana T. Kondratieva, Yegor E. Yegorov, Vera N. Senchenko
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (12): BSR20193094.
Published: 13 December 2019
...). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cell cycle microRNA SCP/CTDSP phosphatases tumor suppressors Lung cancer is the most commonly...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (12): BSR20181404.
Published: 13 December 2019
... of microRNAs (miRNAs) play an important role in developing the disease which can be considered as early stage biomarkers. Since, selective, sensitive, simple and rapid method for detection of these miRNAs in a single test is critical for early diagnosis and efficient therapy of the disease, herein, we report...
Articles
Overcoming cisplatin resistance in osteosarcoma through the miR-199a -modulated inhibition of HIF-1α
Ajimu Keremu, Abudureyimu Aini, Yusufuaji Maimaitirexiati, Zhilin Liang, Pazila Aila, Paizila Xierela, Aikebaier Tusun, Hanikezi Moming, Aihemaitijiang Yusufu
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (11): BSR20170080.
Published: 15 November 2019
... The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cisplatin sensitivity HIF-1α microRNA miR-199a osteosarcoma miRNAs are a class...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190955.
Published: 23 July 2019
... the Creative Commons Attribution License 4.0 (CC BY) . gene polymorphism microRNA tongue squamous cell carcinoma SP1 STAT3 Tongue squamous cell carcinoma (TSCC) is the most common oral cancer; its incidence is about one-third to half of that of all oral cancers [ 1 ]. The pathogenesis of TSCC...
Articles
LncRNA PFAR contributes to fibrogenesis in lung fibroblasts through competitively binding to miR-15a
Jian Sun, Wei Su, Xiaoguang Zhao, Tianjiao Shan, Tongzhu Jin, Yingying Guo, Chao Li, Ruotong Li, Yuhong Zhou, Hongli Shan, Xiaohan Sun, Haihai Liang
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190280.
Published: 19 July 2019
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . fibroblasts large intervening non-coding RNA microRNA Idiopathic pulmonary fibrosis (IPF), the most common idiopathic interstitial pneumonia, is characterized by cell proliferation, interstitial...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190298.
Published: 19 July 2019
...Yingqi Xiao; Hui Liu; Li Chen; Yang Wang; Xiang Yao; Xiaolian Jiang Objective: To investigate whether microRNAs genes’ polymorphisms are associated with arthritis. Methods: The PubMed, Cochrane Library et al. were systematically searched to identify case–control studies, systematic reviews and meta...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190996.
Published: 05 July 2019
... analysis circRNA competitive endogenous RNA microRNA Renal cell carcinoma Renal cell carcinoma (RCC) is one of the most common urological malignancies, accounting for 2–3% of all adult tumors, and is only secondary to bladder cancer. Its incidence is steadily increasing every year [ 1 , 2...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20180695.
Published: 02 July 2019
...Siwen Tang; Hongyu Fu; Qihua Xu; Ying Zhou Colorectal cancer (CRC) is one of the leading cancer-related causes of deaths in the world. Recently, microRNAs have been reported to regulate the tumor growth, invasion and the immunosuppression. In the present study, we found that miR-20a was increased...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20182232.
Published: 14 May 2019
.... Schutten M.T. et al . ( 2017 ) The link between adipose tissue renin-angiotensin-aldosterone system signaling and obesity-associated hypertension . Physiology (Bethesda) 32 , 197 – 209 28404736 18. Hong Z. et al . ( 2017 ) MicroRNA-138 and microRNA-25 down-regulate...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20182485.
Published: 02 May 2019
... (UTR) of APP are associated with the development of AD. Since microRNAs (miRNAs) are involved in the regulation of APP expression, we believe that the APP 3′UTR polymorphism may affect the regulation of APP expression in miRNAs. Results : The levels of miR-101-3p, miR-153-3p, miR-144-3p, miR-381-3p...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (4): BSR20180723.
Published: 16 April 2019
... in microRNAs (miRNAs/miRs) play an important role in the susceptibility of various types of cancers. Objective: To evaluate the association of Single Nucleotide Polymorphisms (SNPs) in miR-146a (rs2910164), miR-196a2 (rs11614913), and miR-499 (rs3746444), with cervical cancer susceptibility in Indian...
Includes: Supplementary data
Articles
Carlos Zaragoza, Marta Saura, Ignacio Hernández, Rafael Ramirez-Carracedo, Francisco García-García, Jose L. Zamorano, Alipio Mangas, Rocio Toro
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (3): BSR20180934.
Published: 15 March 2019
...Carlos Zaragoza; Marta Saura; Ignacio Hernández; Rafael Ramirez-Carracedo; Francisco García-García; Jose L. Zamorano; Alipio Mangas; Rocio Toro A new familial dilated cardiomyopathy (FDCM) was found related to mutations in BAG3 gene. MicroRNAs (miRNAs) represent new targets of FDCM, although...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20180395.
Published: 03 January 2019
... microRNA Migration Proliferation Glioma, as a very common malignant tumor in the human central nervous system, features rapid growth, strong invasion, high mortality and high disability rates, accounting for approximately 60% of adult primary brain tumors [ 1 , 2 ]. Although great advances have...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20181386.
Published: 14 December 2018
... © 2018 The Author(s). 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . colorectal cancer large intervening non-coding RNA microRNA tumorigenesis...
Articles
Yanli Wang, Ke Lv, Hailong Chen, Mei Zhao, Guohua Ji, Yongliang Zhang, Hongqing Cao, Guanghan Kan, Yinghui Li, Lina Qu
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20180233.
Published: 07 December 2018
... the Creative Commons Attribution License 4.0 (CC BY) . Circadian rhythms Clock mutation microRNA Suprachiasmatic nuclei In mammals, circadian rhythms are generated by a central pacemaker in the suprachiasmatic nuclei (SCN) of the hypothalamus [ 1 ]. The molecular mechanism of the circadian...
Articles
Kyoung Hwa Lee, Beom Jin Lim, Victor H. Ferreira, Seo Yeon Min, Yeon-Mi Hong, Jeong-Hyeon Jo, Sang Hoon Han
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20180961.
Published: 07 December 2018
... the Creative Commons Attribution License 4.0 (CC BY) . cytomegalovirus immediate early protein 2 microRNA tissues Human cytomegalovirus (HCMV) replication can cause serious harm in solid organ transplantation (SOT) and hematopoietic stem cell transplantation (HSCT) recipients [ 1–3...
Articles
Bin Sheng, Nian-sheng Lai, Yang Yao, Jin Dong, Zhen-bao Li, Xin-tong Zhao, Jia-qiang Liu, Xue-qin Li, Xing-gen Fang
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20180646.
Published: 21 November 2018
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Biomarker MicroRNA real-time polymerase chain reaction Subarachnoid hemorrhage Stroke Aneurysmal subarachnoid hemorrhage (aSAH) is a serious, life-threatening type of stroke, characterized...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20181090.
Published: 16 November 2018
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Breast cancer Chemoresistance Exosomes MicroRNA Breast cancer is the most common malignant tumor resulting in high mortality amongst females worldwide [ 1 ]. Although chemotherapy plays...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20181578.
Published: 14 November 2018
... nephropathy megalin microRNA renal proximal tubule IgA nephropathy (IgAN) is the most common form of proliferative glomerulopathy worldwide, particularly in Asian populations [ 1 ], with 15–40% of patients progressing to end-stage renal disease (ESRD) within 10–20 years [ 2 ]. Proteinuria...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20180516.
Published: 23 October 2018
... © 2018 The Author(s). 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . autophagy large intervening non-coding RNA microRNA oncogenesis gene therapy...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (5): BSR20180915.
Published: 10 October 2018
... on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . chemoresistance drug resistance hepatocellular carcinoma HCC long non-coding RNA microRNA Hepatocellular carcinoma (HCC) is one of the most frequently diagnosed cancers...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (4): BSR20180448.
Published: 03 July 2018
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bone remodeling compression fluid shear stress mechanical cyclical stretch microgravity microRNA Bone remodeling, which involves a cross-talk between osteoclasts and osteoblasts, is regulated...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (3): BSR20180668.
Published: 21 June 2018
... histological grade, and poor prognosis. Down-regulation of MCM5 inhibited cervical adenocarcinoma cell proliferation. The purpose of the present study is to search and confirm valuable microRNAs (miRNAs), which target MCM5 to modulate cervical adenocarcinoma cell proliferation. In our results, we found...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (3): BSR20180453.
Published: 21 June 2018
... be the underlying mechanisms that link genetic and environmental factors with increased risks of osteoporosis and bone fracture. MicroRNA (miRNA), a major category of small noncoding RNA with 20–22 bases in length, is recognized as one important epigenetic modification. It can mediate post-transcriptional...
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (2): BSR20171208.
Published: 21 March 2018
... in vascular endothelial injury. It is an important factor in the development of diabetes mellitus (DM). The aim of the present study was to screen out the potential candidate microRNAs (miRNAs) in DM patients with BSS by high-throughput sequencing (HTS) and bioinformatics analysis. Human umbilical vein...
Articles
Jin-yan Wang, Qian Zhang, Dan-dan Wang, Wei Yan, Huan-huan Sha, Jian-hua Zhao, Su-jin Yang, He-da Zhang, Jun-chen Hou, Han-zi Xu, Yun-jie He, Jia-hua Hu, Shan-liang Zhong, Jin-hai Tang
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (1): BSR20171265.
Published: 08 February 2018
...(s). 2018 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biomarkers cancer metastases microRNA miR-29a proliferation Mortality caused by cancer...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (6): BSR20171157.
Published: 29 November 2017
... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . diabetic retinopathy dysregulation long noncoding RNA molecular mechanisms microRNA Diabetes mellitus (DM...
Articles
Ming Xu, Zhengmin Yu, Feifei Hu, Hongbing Zhang, Lixin Zhong, Lei Han, Yan An, Baoli Zhu, Hengdong Zhang
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (5): BSR20171111.
Published: 31 October 2017
... chronic lead exposure diagnosis microRNA Lead (Pb) is a common material existing in the Earth, and widely utilized in industry. The most important artificial sources for lead emission are considered to be mining and metal smelting [ 1 , 2 ]. As a classical environmental and occupational toxicant...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (5): BSR20170768.
Published: 11 October 2017
... 2017 15 08 2017 29 08 2017 01 09 2017 © 2017 The Author(s). 2017 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . microRNA miRNA sequence...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (4): BSR20170149.
Published: 31 August 2017
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . B lymphocyte IL-10 microRNA A fraction of B cells in the peripheral blood system expresses thrombospondin 1 (TSP1). These B cells have the immune suppressive function on other effector immune...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (3): BSR20160404.
Published: 07 June 2017
... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . hexokinase 2 microRNA miR-143 oral cancer Oral squamous cell carcinoma (OSCC) is the most common head and neck neoplasm, representing 95% of all forms...
Articles
Journal:
Bioscience Reports
Biosci Rep (2016) 36 (3): e00351.
Published: 30 June 2016
... . The objective was to find out if any miRNA could distinguish patients with unstable plaque from patients with stable plaque after acute coronary syndrome. coronary artery disease diagnosis biomarker microRNA Troponin (cTn) measurements are commonly used by clinicians to diagnose patients. cTn...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2015) 35 (5): e00245.
Published: 10 September 2015
.... In the present study, miR-146 promoted spontaneous differentiation of neural stem cells (NSCs), and this mechanism was influenced by miR-146 , as well as its target (notch 1) and downstream gene. cell proliferation differentiation microRNA neural stem cells miRNAs are a fundamental class...
Articles
Journal:
Bioscience Reports
Biosci Rep (2011) 31 (6): 449–455.
Published: 15 September 2011
.... This observation is also confirmed using head and neck cancer patient samples. These results provide a critical mechanism of Twist1-induced EMT and cancer stemness in cancer cells through chromatin remodelling. The role of hypoxia and microRNAs in regulating EMT and cancer stemness is also discussed. 1...
