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Keywords: metastasis
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Biosci Rep (2024) 44 (1): BSR-2020-0367_RET.
Published: 31 January 2024
... © 2024 The Author(s). 2024 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cervical cancer LINC00636 metastasis NM23 This article is being...
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Biosci Rep (2023) 43 (9): BSR20230057.
Published: 11 September 2023
... promoted cancer cell migration in vitro and metastasis in vivo . The latest research from Sabine’s team has demonstrated that in H1299 lung cancer cells, the mechanism by which ITPKA promoted migration and invasion was predominantly depending on the ability of binding to F-actin, which will induce cancer...
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Biosci Rep (2023) 43 (4): BSR-2017-0837_RET.
Published: 21 April 2023
... AKT Hepatocarcinoma Metastasis MiR-500a This Retraction follows an Expression of Concern relating to this article previously published by Portland Press. This article is being retracted from Bioscience Reports , at the request of the Editor-in-Chief and the Editorial Board, following...
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Biosci Rep (2023) 43 (4): BSR-2015-0258_RET.
Published: 21 April 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . TMEM14A cell cycle metastasis ovarian cancer This Retraction follows...
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Biosci Rep (2023) 43 (3): BSR-2016-0521_RET.
Published: 01 March 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . epithelial-mesenchymal transition Flot2 metastasis microRNA-802 prostate...
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Biosci Rep (2023) 43 (2): BSR20222150.
Published: 09 February 2023
... License 4.0 (CC BY) . actin cell invasion Ins(1,4,5)P3 ITPKA metastasis migration Ins(1,4,5)P 3 -kinase-A (ITPKA or InsP 3 kinase) was first described and characterized by Irvine et al. in 1986 and cloned by Takazawa et al. in 1990 [ 1 , 2 ]. The authors found that ITPKA phosphorylates...
Includes: Supplementary data
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Biosci Rep (2023) 43 (2): BSR-2015-0258_EOC.
Published: 09 February 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cell cycle metastasis ovarian cancer THEM14A The Editorial Office has...
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Biosci Rep (2022) 42 (9): BSR-2019-1062_RET.
Published: 21 September 2022
... © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Apoptosis Breast cancer Cosmc Metastasis Proliferation Tn and T glycans...
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Biosci Rep (2022) 42 (7): BSR-2019-1611_RET.
Published: 27 July 2022
... © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . AKT3 breast cancer metastasis miRNA NF-κB This article is being...
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Biosci Rep (2022) 42 (2): BSR20212622.
Published: 11 February 2022
... (Axio observer 7). chitosan Iron oxide nanoparticles metastasis Cancer remains one of the leading causes of mortality even though substantial advancement in research over the last decades has taken place [ 1 ]. Overexpressing surface receptors are ideal marks for targeting and imaging...
Includes: Supplementary data
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Biosci Rep (2021) 41 (12): BSR20211577.
Published: 17 December 2021
... metastasis ribosomal proteins Ribosomes Protein synthesis is a highly regulated and coordinated process involving the action of ribosomes and a set of translation factors. Ribosome biogenesis occurs in the nucleolus and requires the action of 80 ribosomal proteins (RPs), 4 ribosomal RNAs (rRNAs...
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Biosci Rep (2021) 41 (10): BSR20211137.
Published: 19 October 2021
... and 6 [ 12 ]. Silencing CCT3 inhibited the proliferation, stopped cell cycle and induced apoptosis in papillary thyroid carcinoma cells [ 13 ]. In breast cancer, Xu et al. have reported that CCT3 knockdown significantly inhibited activity of NF-κB and decreased the proliferation and metastasis ability...
Includes: Supplementary data
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Biosci Rep (2021) 41 (10): BSR20211056.
Published: 06 October 2021
... after treatment with digoxin, with an increase in autophagosome foci. In addition, digoxin inhibited the phosphorylation of Akt, mTOR and p70S6K, signaling molecules of the PI3K/Akt pathway that are known to be involved in tumor cell survival, proliferation, metastasis and autophagy. Our findings...
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Biosci Rep (2021) 41 (2): BSR20203121.
Published: 03 February 2021
...Haomeng Zhang; Jiao Wang; Yulong Yin; Qingjie Meng; Yonggang Lyu Triple-negative breast cancer (TNBC) is the most malignant and fatal subtype of breast cancer, which has characterized by negativity expression of ER, PR, and HER2. Metastasis is the main factor affecting the prognosis of TNBC...
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Biosci Rep (2021) 41 (1): BSR20201178.
Published: 22 January 2021
... into five groups: Vehicle, cyclophosphamide (CTX, 20 mg/kg), TSRP (25 mg/kg), TSRP (50 mg/kg) and TSRP (100 mg/kg) groups for 14 days’ treatment. In addition, the melanoma metastasis in lung in vivo of TSRP was detected in A375 tail vein injection mice, and the histopathalogical analysis of the lung...
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Biosci Rep (2021) 41 (1): BSR20201539.
Published: 04 January 2021
... was assessed by RT-PCR and Western blot. Besides, Kaplan–Meier survival analysis was recruited to explore the association between TNS1 and NSCLC. Cell growth was analyzed by MTT and flow cytometry assay, while cell metastasis was determined by wound healing and transwell assays. The targeting relationship...
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Biosci Rep (2020) 40 (10): BSR20200367.
Published: 30 October 2020
...Yue Zhong; Qiang Lu; Wei Qiu; Yan Luo Background: Metastasis is a major obstacle in treatment of cervical cancer, and long non-coding RNA (lncRNA) mediated regulatory effect on associated genes expression is found to be involved in metastasis. However, its mechanisms have not been fully elucidated...
Includes: Supplementary data
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Biosci Rep (2020) 40 (8): BSR20200437.
Published: 25 August 2020
... detected in HCT116 and HT29 cell lines. In HCT116 and HT29 cells, CD133 + CD44 + cells not only shared the extensive tumorigenic potential of LT-TICs but also functionally reproduced the behaviors of LT-TICs that drive tumor metastasis (TM) formation, suggesting that CD133 + CD44 + cells are a typical...
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Biosci Rep (2020) 40 (6): BSR20191062.
Published: 17 June 2020
...Jun Liu; Feng Xu; Jie Li; Hongchuan Jiang Objectives: The high mortality of breast cancer (BC) is associated with the strong metastatic properties of primary breast tumor cells. The present study was conducted in order to clarify the effect of Cosmc on the growth and metastasis of BC cell lines...
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Biosci Rep (2020) 40 (4): BSR20200390.
Published: 28 April 2020
...Yi Yao; Nan Li Background: Metastasis and chemoresistance indicate a poor prognosis in colorectal cancer (CRC) patients. However, the mechanisms that lead to the development of chemoresistance and metastasis in CRC remain unclear. Materials and methods: We combined clinical and experimental studies...
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Biosci Rep (2020) 40 (3): BSR20200049.
Published: 27 March 2020
... cortical carcinoma (ACC). Methods: A ceRNA network was established to identify the ceRNAs involved in metastasis of ACC based on 92 samples from TCGA, including 18 cases of metastasis and 74 cases of non-metastatic primary tumors. And the algorithm “cell type identification by estimating relative subsets...
Includes: Supplementary data
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Biosci Rep (2020) 40 (3): BSR20200265.
Published: 20 March 2020
..., ErbB, RHOA, Notch, BMP, Hippo, AMPK, NF-κB, MAPK and JNK. Subsequently, we discussed the biological function of these pathways in pathophysiological aspects of CRC, such as proliferation, apoptosis and metastasis. Finally, we summarized important interactions among these pathways in CRC. We believe...
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Biosci Rep (2020) 40 (2): BSR20194335.
Published: 28 February 2020
...Dan-dan Hu; Hai-ling Chen; Li-ming Lou; Hong Zhang; Guo-liang Yang The processes that lead to lung adenocarcinoma (LUAD) metastasis are poorly characterized. Spindle and kinetochore associated complex subunit 3 (SKA3) plays a key role in cervical cancer development, but its contribution to LUAD...
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Biosci Rep (2019) 39 (9): BSR20190489.
Published: 03 September 2019
... and cells. High LUCAT1 expression was strongly associated with advanced stages and poor prognosis of TNBC. LUCAT1 contributed to TNBC development through accelerating cell proliferation, cell cycle progression and metastasis as well as attenuating cell apoptosis. Moreover, miR-5702 was proved to directly...
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Biosci Rep (2019) 39 (8): BSR20191611.
Published: 23 August 2019
... 2019 05 08 2019 © 2019 The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . AKT3 breast cancer metastasis miRNA NF-κB...
Includes: Supplementary data
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Biosci Rep (2019) 39 (7): BSR20190634.
Published: 12 July 2019
... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . AJUBA CCND1 HEG1 Lung cancer Metastasis microRNA-193b Despite the remarkable development of lung cancer therapies, lung cancer has been classified...
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Biosci Rep (2019) 39 (6): BSR20181339.
Published: 04 June 2019
... role in epithelial cancer progression and metastasis including cervical carcinoma, which have dramatic phenotypic changes by the loss of epithelial marker proteins such as E-cadherin and the acquisition of mesenchymal marker protein such as vimentin [ 6 , 7 ]. EMT is thought to be critical...
Includes: Supplementary data
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Biosci Rep (2019) 39 (5): BSR20181573.
Published: 21 May 2019
... epithelial to mesenchymal transition and cancer metastasis via cis-regulating FOXA2 and inactivating Wnt/beta-catenin signaling . Oncogene 37 , 1445 – 1456 10.1038/s41388-017-0041-y 29311643 12. Zhou T. et al . ( 2018 ) Runt-related transcription factor 1 (RUNX1) promotes TGF-beta...
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Biosci Rep (2019) 39 (4): BSR20190016.
Published: 16 April 2019
... inhibiting the protein expressions of several transcriptional or surface markers of cancer stem cells. These findings first suggest that CHTOP, as a highly expressed protein in ovarian cancer, is closely associated with the malignant phenotypes of epithelial ovarian cancer cells, including metastasis...
Includes: Supplementary data
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Biosci Rep (2019) 39 (4): BSR20182186.
Published: 02 April 2019
... of the present study was to investigate SNHG20 clinical significance and its underlying mechanism in proliferation and metastasis in EOC. The expression level of SNHG20 was identified via in situ hybridization (ISH) and quantitative RT-PCR (qRT-PCR). The proliferative and metastatic capacities by silencing...
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Biosci Rep (2019) 39 (3): BSR20181937.
Published: 15 March 2019
...Xian-Ping Cui; Chuan-Xi Wang; Zhi-Yi Wang; Jian Li; Ya-Wen Tan; Song-Tao Gu; Cheng-Kun Qin LncRNA TP73 antisense RNA 1T (TP73-AS1) plays an important role in human malignancies. However, the levels of TP73-AS1 and its functional mechanisms in pancreatic cancer metastasis remain unknown...
Includes: Supplementary data
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Biosci Rep (2019) 39 (3): BSR20181377.
Published: 15 March 2019
...Jin-yan Wang; Li-juan Chen Cervical cancer (CC) with early metastasis of the primary tumor results in poor prognosis and poor therapeutic outcomes. MicroRNAs (miRNAs) are small, noncoding RNA molecules that play a substantial role in regulating gene expression post-transcriptionally and influence...
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Biosci Rep (2019) 39 (3): BSR20181639.
Published: 06 March 2019
... correlated with the International Federation of Gynecology and Obstetrics (FIGO) stage, histological grade and lymph node metastasis, but not with age, histological type, and tumor size. Kaplan–Meier survival analysis suggested that high TRIM44 expression was associated with poor prognosis. Patients highly...
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Biosci Rep (2019) 39 (1): BSR20180999.
Published: 11 January 2019
... overexpression was strongly associated with poor clinical outcomes. Then the loss/gain-of-function assays elucidated that TP73-AS1 contributed to cell proliferation, migration, and invasion in vitro , and the in vivo experiments illustrated that its knockdown inhibited tumor growth and metastasis. What was more...
Includes: Supplementary data