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Keywords: metastasis
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Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (9): BSR20230057.
Published: 11 September 2023
... promoted cancer cell migration in vitro and metastasis in vivo . The latest research from Sabine’s team has demonstrated that in H1299 lung cancer cells, the mechanism by which ITPKA promoted migration and invasion was predominantly depending on the ability of binding to F-actin, which will induce cancer...
Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (4): BSR-2017-0837_RET.
Published: 21 April 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . AKT Hepatocarcinoma Metastasis MiR-500a This Retraction follows...
Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (4): BSR-2015-0258_RET.
Published: 21 April 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . TMEM14A cell cycle metastasis ovarian cancer This Retraction follows...
Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (3): BSR-2016-0521_RET.
Published: 01 March 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . epithelial-mesenchymal transition Flot2 metastasis microRNA-802 prostate...
Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (2): BSR-2015-0258_EOC.
Published: 09 February 2023
... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . cell cycle metastasis ovarian cancer THEM14A The Editorial Office has...
Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (2): BSR-2017-0837_EOC.
Published: 09 February 2023
... AKT Hepatocarcinoma Metastasis Mir-500a PTEN The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. The Figure 3C Inhibitor NC...
Articles
Lukas Küster, Themistoklis Paraschiakos, Kader Ebru Karakurt, Udo Schumacher, Björn-Philipp Diercks, Sabine Windhorst
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (2): BSR20222150.
Published: 09 February 2023
... one metastasis is shown (see also magnification in the lower panel), which is embedded in normal lung tissue. Figure 1 Knock-down of ITPKA strongly reduces formation of distant metastasis in mice ( A ) H1299 control and H1299 ITPKA knock-down cells [ 4 ] were subcutaneously injected...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (9): BSR-2019-1062_RET.
Published: 21 September 2022
... © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Apoptosis Breast cancer Cosmc Metastasis Proliferation Tn and T glycans...
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (7): BSR-2019-1611_RET.
Published: 27 July 2022
... the article. The Editor-in-Chief and Editorial Board agree with the Retraction. AKT3 breast cancer metastasis miRNA NF-κB © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative...
Articles
Polymeric biocompatible iron oxide nanoparticles labeled with peptides for imaging in ovarian cancer
In Collection
Bionanotechnology and Synthetic Biology: applications in precision medicine and allied fields
Deepshikha Shahdeo, Akanksha Roberts, Veerbhan Kesarwani, Milena Horvat, Raghuraj Singh Chouhan, Sonu Gandhi
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (2): BSR20212622.
Published: 11 February 2022
... nanoparticles metastasis Cancer remains one of the leading causes of mortality even though substantial advancement in research over the last decades has taken place [ 1 ]. Overexpressing surface receptors are ideal marks for targeting and imaging of cancer cells. To develop efficient imaging probes...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (12): BSR20211577.
Published: 17 December 2021
... Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis Cancer cell survival metastasis ribosomal proteins Ribosomes Protein synthesis is a highly regulated and coordinated process involving the action...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (10): BSR20211137.
Published: 19 October 2021
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . CCT3 cell survival HNSCC metastasis prognostic factor Head and neck cancer (HNC) is a common malignant worldwide and causes more than 600,000 new cases every year [ 1 ]. Head and neck squamous...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (10): BSR20211056.
Published: 06 October 2021
... after treatment with digoxin, with an increase in autophagosome foci. In addition, digoxin inhibited the phosphorylation of Akt, mTOR and p70S6K, signaling molecules of the PI3K/Akt pathway that are known to be involved in tumor cell survival, proliferation, metastasis and autophagy. Our findings...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (8): BSR-2018-1175_RET.
Published: 06 August 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Cell growth Gastric cancer Metastasis MicroRNA-27a Neoadjuvant...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20193514.
Published: 26 July 2021
...Wei Mai; Lingyu Kong; Hongwei Yu; Junjie Bao; Chunyu Song; Guofan Qu Aim: Typical features of human osteosarcoma are highly invasive and migratory capacities. Our study aimed to investigate the roles of glycogen synthase kinase 3β (GSK3β) in human osteosarcoma metastasis. Methods: GSK3β expressions...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (2): BSR20203121.
Published: 03 February 2021
...Haomeng Zhang; Jiao Wang; Yulong Yin; Qingjie Meng; Yonggang Lyu Triple-negative breast cancer (TNBC) is the most malignant and fatal subtype of breast cancer, which has characterized by negativity expression of ER, PR, and HER2. Metastasis is the main factor affecting the prognosis of TNBC...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20201178.
Published: 22 January 2021
... into five groups: Vehicle, cyclophosphamide (CTX, 20 mg/kg), TSRP (25 mg/kg), TSRP (50 mg/kg) and TSRP (100 mg/kg) groups for 14 days’ treatment. In addition, the melanoma metastasis in lung in vivo of TSRP was detected in A375 tail vein injection mice, and the histopathalogical analysis of the lung...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20201539.
Published: 04 January 2021
... was assessed by RT-PCR and Western blot. Besides, Kaplan–Meier survival analysis was recruited to explore the association between TNS1 and NSCLC. Cell growth was analyzed by MTT and flow cytometry assay, while cell metastasis was determined by wound healing and transwell assays. The targeting relationship...
Articles
Hui Luo, Jian Li, Qi Lin, Xiaojun Xiao, Yang Shi, Xiuqin Ye, Zhanghong Wei, Yingying Liu, Jinfeng Xu
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (11): BSR20201854.
Published: 02 November 2020
... suggested that PRR11 was up-regulated in breast cancer. Silencing PRR11 mediated by US showed a higher efficiency than by Lipofectamine 3000. SiPRR11 transfected by Lipofectamine 3000 suppressed cells growth and metastasis, while promoted cell apoptosis. Moreover, E-cadherin (E-cad) and Bax expressions were...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20200367.
Published: 30 October 2020
...Yue Zhong; Qiang Lu; Wei Qiu; Yan Luo Background: Metastasis is a major obstacle in treatment of cervical cancer, and long non-coding RNA (lncRNA) mediated regulatory effect on associated genes expression is found to be involved in metastasis. However, its mechanisms have not been fully elucidated...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR20200437.
Published: 25 August 2020
... detected in HCT116 and HT29 cell lines. In HCT116 and HT29 cells, CD133 + CD44 + cells not only shared the extensive tumorigenic potential of LT-TICs but also functionally reproduced the behaviors of LT-TICs that drive tumor metastasis (TM) formation, suggesting that CD133 + CD44 + cells are a typical...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR-20190159_COR.
Published: 07 August 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Isorhamnetin Lung cancer Metastasis Epithelial-mesenchymal transition (EMT...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (7): BSR-20181175_EOC.
Published: 29 July 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Cell growth Efficacy Gastric cancer Metastasis MicroRNA-27a Neoadjuvant...
Articles
Runzhi Huang, Gaili Yan, Hanlin Sun, Jie Zhang, Dianwen Song, Rui Kong, Penghui Yan, Peng Hu, Aiqing Xie, Siqiao Wang, Juanwei Zhuang, Huabin Yin, Tong Meng, Zongqiang Huang
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20201001.
Published: 15 July 2020
... of cancer deaths worldwide. Its high-frequency metastasis and relapse rate lead to the poor survival of HCC patients. However, the mechanism of HCC metastasis is still unclear. Alternative splicing events (ASEs) have a great effect in cancer development, progression and metastasis. We downloaded RNA...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (7): BSR-20190159_EOC.
Published: 30 June 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Isorhamnetin Lung cancer Metastasis Epithelial-mesenchymal transition (EMT...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20191062.
Published: 17 June 2020
...Jun Liu; Feng Xu; Jie Li; Hongchuan Jiang Objectives: The high mortality of breast cancer (BC) is associated with the strong metastatic properties of primary breast tumor cells. The present study was conducted in order to clarify the effect of Cosmc on the growth and metastasis of BC cell lines...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20200390.
Published: 28 April 2020
...Yi Yao; Nan Li Background: Metastasis and chemoresistance indicate a poor prognosis in colorectal cancer (CRC) patients. However, the mechanisms that lead to the development of chemoresistance and metastasis in CRC remain unclear. Materials and methods: We combined clinical and experimental studies...
Articles
Runzhi Huang, Ziqi Liu, Tingli Tian, Dianwen Song, Penghui Yan, Huabin Yin, Peng Hu, Xiaolong Zhu, Yihan Liu, Zhenyu Li, Tong Meng, Jie Zhang, Zongqiang Huang
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (3): BSR20200049.
Published: 27 March 2020
... cortical carcinoma (ACC). Methods: A ceRNA network was established to identify the ceRNAs involved in metastasis of ACC based on 92 samples from TCGA, including 18 cases of metastasis and 74 cases of non-metastatic primary tumors. And the algorithm “cell type identification by estimating relative subsets...
Includes: Supplementary data
Articles
Mao-lin Wan, Yu Wang, Zhi Zeng, Bo Deng, Bi-sheng Zhu, Ting Cao, Yu-kun Li, Jiao Xiao, Qi Han, Qing Wu
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (3): BSR20200265.
Published: 20 March 2020
..., ErbB, RHOA, Notch, BMP, Hippo, AMPK, NF-κB, MAPK and JNK. Subsequently, we discussed the biological function of these pathways in pathophysiological aspects of CRC, such as proliferation, apoptosis and metastasis. Finally, we summarized important interactions among these pathways in CRC. We believe...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (3): BSR20192826.
Published: 18 March 2020
... 10 02 2020 © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Apoptosis Isorhamnetin Metastasis PI3K/Akt/mTOR Prostate...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (3): BSR20194342.
Published: 09 March 2020
...Shuai Wu; Jian Xie; Hao Shi; Zi-wei Wang Objective: Metastasis and chemoresistance indicate treatment fail and progresses in gastric cancer (GC) patients. However, the molecular mechanisms of chemoresistance and metastasis remain unclear in GC. Thus, identifying the biological indicators...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20194335.
Published: 28 February 2020
...Dan-dan Hu; Hai-ling Chen; Li-ming Lou; Hong Zhang; Guo-liang Yang The processes that lead to lung adenocarcinoma (LUAD) metastasis are poorly characterized. Spindle and kinetochore associated complex subunit 3 (SKA3) plays a key role in cervical cancer development, but its contribution to LUAD...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (9): BSR20190159.
Published: 20 September 2019
...Wei Luo; Qingbin Liu; Nan Jiang; Mingquan Li; Li Shi In the present study, we investigated the potential effects of Isorhamnetin on the growth and metastasis of A549 human lung cancer cells, as well as the underlying mechanism. Treatment with Isorhamnetin exhibited a dose- and time-dependent...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (9): BSR20190489.
Published: 03 September 2019
... and cells. High LUCAT1 expression was strongly associated with advanced stages and poor prognosis of TNBC. LUCAT1 contributed to TNBC development through accelerating cell proliferation, cell cycle progression and metastasis as well as attenuating cell apoptosis. Moreover, miR-5702 was proved to directly...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (8): BSR20191611.
Published: 23 August 2019
... 2019 05 08 2019 © 2019 The Author(s). 2019 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . AKT3 breast cancer metastasis miRNA NF-κB...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (8): BSR20190906.
Published: 02 August 2019
... RNA Metastasis Prognosis Proliferation Wnt/β-catenin signaling Human ovarian cancer, one of the most common gynecologic neoplasms, is responsible for the highest mortality among women, and represents a major concern for women’s health worldwide [ 1 , 2 ]. And nearly nine in ten female...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20190634.
Published: 12 July 2019
... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . AJUBA CCND1 HEG1 Lung cancer Metastasis microRNA-193b Despite the remarkable development of lung cancer therapies, lung cancer has been classified...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20182082.
Published: 05 July 2019
...Xue Yang; Gaopei Meng In order to optimize patient-tailored chemotherapy, a non-small-cell lung cancer (NSCLC)-liver metastasis patient-derived tumor xenograft (PDTX) model is developed. Computed tomography (CT)-guided NSCLC percutaneous biopsy was subcutaneously inoculated into the flank of non...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (6): BSR20190077.
Published: 10 June 2019
... Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . endometrial carcinoma metastasis miR-940 MRVI1 proliferation R-5′-AACGCTTCACGAATTTGCGT -3′ Endometrial cancer (EC) is one of the most common reproductive...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (6): BSR20181339.
Published: 04 June 2019
... role in epithelial cancer progression and metastasis including cervical carcinoma, which have dramatic phenotypic changes by the loss of epithelial marker proteins such as E-cadherin and the acquisition of mesenchymal marker protein such as vimentin [ 6 , 7 ]. EMT is thought to be critical...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20181573.
Published: 21 May 2019
... epithelial to mesenchymal transition and cancer metastasis via cis-regulating FOXA2 and inactivating Wnt/beta-catenin signaling . Oncogene 37 , 1445 – 1456 10.1038/s41388-017-0041-y 29311643 12. Zhou T. et al . ( 2018 ) Runt-related transcription factor 1 (RUNX1) promotes TGF-beta...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20181175.
Published: 21 May 2019
...Chunlei Xu; Hong Cheng; Na Li; Ning Zhou; Xushan Tang Objective: The aim of the present study is to investigate the relationship between microRNA-27a (miR-27a) and the efficacy of neoadjuvant chemotherapy in gastric cancer (GC) and its mechanism in the growth and metastasis of GC cells. Methods...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (4): BSR20182384.
Published: 17 April 2019
... . drug resistance growth metastasis sorafenib Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third leading cause of cancer-related mortality worldwide [ 1 ]. During the past two decades, the great advancement of HCC treatment has been achieved, including surgical...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (4): BSR20190016.
Published: 16 April 2019
... inhibiting the protein expressions of several transcriptional or surface markers of cancer stem cells. These findings first suggest that CHTOP, as a highly expressed protein in ovarian cancer, is closely associated with the malignant phenotypes of epithelial ovarian cancer cells, including metastasis...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (4): BSR20182186.
Published: 02 April 2019
... of the present study was to investigate SNHG20 clinical significance and its underlying mechanism in proliferation and metastasis in EOC. The expression level of SNHG20 was identified via in situ hybridization (ISH) and quantitative RT-PCR (qRT-PCR). The proliferative and metastatic capacities by silencing...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (3): BSR20181937.
Published: 15 March 2019
...Xian-Ping Cui; Chuan-Xi Wang; Zhi-Yi Wang; Jian Li; Ya-Wen Tan; Song-Tao Gu; Cheng-Kun Qin LncRNA TP73 antisense RNA 1T (TP73-AS1) plays an important role in human malignancies. However, the levels of TP73-AS1 and its functional mechanisms in pancreatic cancer metastasis remain unknown...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (3): BSR20181377.
Published: 15 March 2019
...Jin-yan Wang; Li-juan Chen Cervical cancer (CC) with early metastasis of the primary tumor results in poor prognosis and poor therapeutic outcomes. MicroRNAs (miRNAs) are small, noncoding RNA molecules that play a substantial role in regulating gene expression post-transcriptionally and influence...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (3): BSR20181639.
Published: 06 March 2019
... correlated with the International Federation of Gynecology and Obstetrics (FIGO) stage, histological grade and lymph node metastasis, but not with age, histological type, and tumor size. Kaplan–Meier survival analysis suggested that high TRIM44 expression was associated with poor prognosis. Patients highly...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20180999.
Published: 11 January 2019
... overexpression was strongly associated with poor clinical outcomes. Then the loss/gain-of-function assays elucidated that TP73-AS1 contributed to cell proliferation, migration, and invasion in vitro , and the in vivo experiments illustrated that its knockdown inhibited tumor growth and metastasis. What was more...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (1): BSR20181165.
Published: 08 January 2019
...Wei Li; Yubo Zhou Intratumoral hypoxia is a well-known feature of solid cancers and constitutes a major contributor to cancer metastasis and poor outcomes including melanoma. Leucine-rich repeats and Ig-like domains 1 (LRIG1) participate in the aggressive progression of several tumors, where its...
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