... access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . calcium signalling membrane fusion trafficking The plasma membrane is a protective barrier for cells, made up...

...-2). These viruses are enveloped and utilize membrane fusion to deliver their genetic material to the host cell. Like other class one fusion proteins, LASV-mediated membrane fusion occurs through an orchestrated sequence of conformational changes in its GPC. The receptor-binding subunit, GP1, first...

...Jiajie Diao; Yuji Ishitsuka; Woo-Ri Bae Membrane fusion is one of the most important cellular processes by which two initially distinct lipid bilayers merge their hydrophobic cores, resulting in one interconnected structure. Proteins, called SNARE (soluble N -ethylmaleimide-sensitive factor...

.... The relative purity was further confirmed by the absence of markers for other membranous organelles including EEA1 (early endosomes), p115 (Golgi) and Rab11 (recycling endosomes). late endocytic organelle late endosome lysosome-associated membrane protein-1 (LAMP-1) membrane fusion membrane...

... in multiple ways: (a) as alternate receptor(s) for CD4-independent entry in neuronal and other cell types, (b) viral transmission, and (c) gp120-gp41-mediated membrane fusion. However, the exact mechanism(s) by which GSLs support fusion is still elusive. This article will focus on the contribution of target...

... of influenza virus (which requires a low pH-dependent step to enter target cells) was affected by dextran sulfate, again the higher molecular weight compound showing a more pronounced inhibitory effect. © 2001 Plenum Publishing Corporation 2001 Influenza Sendai membrane fusion dextran sulfate...

..., the experimental evidence is reviewed, and discussed in terms of the underlying molecular mechanisms of fusion, and of the possible physiological relevance of these findings. © 2000 Plenum Publishing Corporation 2000 Phospholipase C sphingomyelinase membrane fusion liposomes model membranes non...

... into a model for the mechanism by which fusion peptides are proposed to assist in biological membrane fusion. © 2000 Plenum Publishing Corporation 2000 membrane fusion lipid-protein interaction secondary structure conformational change thermodynamics HIV gp41 influenza haemagglutinin viral...

... have revealed lipids forming inverted non-lamellar phases to be important in controlling membrane fusion. However, the underlying molecular level mechanisms have remained controversial. While this review is focused on presenting one possible mechanism, involving so-called extended lipid conformation...

... surface and dissociates therein. Other regions, besides the N-terminal fusionpeptide, which include the core region and an internal fusion peptide inparamyxoviruses, are directly involved in the actual membrane fusion event, suggesting an “umbrella” like model for the membrane inducedconformational change...

... of a fusion pore by viral glycoproteins. © 2000 Plenum Publishing Corporation 2000 membrane fusion viral fusion HIV-1 gp41 influenza hemagglutinin Sendai virus Semliki forest virus vesicular stomatitis virus fusion peptide peptide–lipid interaction Wimley–White hydrophobicity scale...

...Danika L. LeDuc; Yeon-Kyun Shin A number of different viral spike proteins, responsible for membrane fusion, show striking similarities in their core structures. The prospect of developing a general structure-based mechanism seems plausible in light of these newly determined structures. Influenza...

...Eva-Isabelle Pécheur; Olaf Maier; Dick Hoekstra Intracellular membrane fusion events require a general protein machinery that functions in vesicular traffic and in assembly and maintenance of organelles. An array of cytosolic and integral membrane proteins are currently identified...

... fusion viral glycoprotein heptad repeats proteolytic processing glycosylation oligomerization fusion peptides Bioscience Reports, Vol. 20, No. 6, 2000 MINI REVIEW Virus Membrane Fusion Proteins: Biological Machines that Undergo a Metamorphosis Rebecca Ellis Dutch,1 Theodore S. Jardetzky,2...

... virus erythrocytes erythrocyte ghosts membrane fusion fluorescence dequenching Bioscience Reports, Vol. 18, No. 2, 1998 Sendai Virus Fusion Activity as Modulated by Target Membrane Components Isabel Nunes-Correia,1,3 Joao Ramalho-Santos,2,3 and Maria C. Pedroso de Lima1,3,4 Received January 19...

... are not solely a function of the lipid headgroup but also require a structure with three long acyl chains. The reduced leakage is not related to a loss in monolayer curvature strain. © 1997 Plenum Publishing Corporation 1997 N-acyl-phosphatidylethanolamine Sendai virus Membrane fusion lipid...

... -lysine phosphatidylserine pyrene-labelled phosphatidylethanolamine membrane fusion liposome leakage Abbreviations DSC, differential scanning calorimetry; DEPE, dielaidoylphosphatidylethanolamine; POPS, 1-palmitoyl-2-oleoylphosphatidylethanolamine; DMPS, dimyristoylphosphatidylserine; DMPE...

... bilayer. 29 12 1993 7 1 1994 © 1994 Plenum Publishing Corporation 1994 membrane fusion influenza lipid phase behaviour hexagonal phase membrane defects Abbreviations: IMI, inverted micellar intermediate; ILA, interlamellar attachment; H II , inverted hexagonal phase...

... made for both viruses. These results stress the importance of dehydration and hydrophobic interactions in the fusion activity of influenza and Sendai viruses, and show that these factors may be generally involved in membrane fusion events mediated by many other lipid enveloped viruses. 20 11 1993...

...Dick Hoekstra; Jan Willem Kok Enveloped viruses infect cells by a mechanism involving membrane fusion. This process is mediated and triggered by specific viral membrane glycoproteins. Evidence is accumulating that fusion of intracellular membranes, as occurs during endocytosis and transport between...

...C. Kempf; M. R. Michel; U. Kohler; H. Koblet; H. Oetliker The mechanism of the processes leading to membrane fusion is as yet unknown. In this report we demonstrate that changes in membrane potential and potassium fluxes correlate with Semliki Forest virus induced cell-cell fusion at mildly acidic...

... dipeptide, Z-Ser-Leu-NH 2 , reduces measles virus cytopathic effect (CPE) in Vero cells. The mechanism by which this peptide reduces the CPE is not known, although some peptides which raise the bilayer to hexagonal phase transition temperature of phospholipids inhibit membrane fusion. virus inhibitors...

.... These differences are discussed in terms of molecular mechanisms of fusion. 7 7 1987 © 1987 Plenum Publishing Corporation 1987 exocytosis fusion membrane fusion phospholipid Bioscience Reports, Vol. 7, No. 4, 1987 Molecular Mechanisms of Membrane Fusion: Steps During Phospholipid...

... Publishing Corporation 1986 membrane fusion erythrocyte ghosts Sendai virus fluorescence Bioscience Reports, Vol. 6, No. 11, 1986 Use of a Fluorescence Assay to Monitor the Kinetics of Fusion Between Erythrocyte Ghosts, as Induced by Sendai Virus Dick Hoekstra I and Karin Klappe Received December...