...Zhihao Xie; Zhiying Xie; Nicolas Pineda Trujillo; Ting Yang; Chunxia Yang Chaihu-Shugan-San (CHSGS), a noted traditional Chinese medicine formula, has been used as a complementary and alternative therapy for liver fibrosis. However, the antifibrotic mechanisms of CHSGS still remain unclear. Thus...

...Thanh Minh Dang; Trinh Van Le; Huy Quang Do; Van Thuan Nguyen; Ai Xuan Le Holterman; Loan Tung Thi Dang; Nhan Chinh Lu Phan; Phuc Van Pham; Son Nghia Hoang; Long Thanh Le; Gabriele Grassi; Nhung Hai Truong Liver fibrosis (LF) mortality rate is approximately 2 million per year. Irrespective...

... AFP and PLT levels with LS values were observed when both variables were included in the multivariate analysis models. Receiver operation characteristic (ROC) analysis indicated that the combination of AFP and PLT levels could enhance the predictive performance of liver fibrosis (area under the curve...

... such as metabolic disorders and hemolysis in vivo , thus hampering its clinical use. The present study investigated the toxicity-reducing effects of liposome encapsulation of pure SSd and the therapeutic action of SSd-loaded liposomes (Lipo-SSd) in liver fibrosis in vitro and in vivo . Lipo-SSd (diameter, 31.7...

...Wei Hou; Michael G. Janech; Philip M. Sobolesky; Alison M. Bland; Salma Samsuddin; William Alazawi; Wing-Kin Syn Noninvasive biomarkers are clinically useful for evaluating liver fibrosis stage in patients with nonalcoholic fatty liver disease (NAFLD). The aim of the present study was to compare...

...Yanan Gao; Xuguang Li; Qiang Gao; Li Fan; Haobin Jin; Yueping Guo Olive oil could attenuate carbon tetrachloride (CCl 4 ) induced liver fibrosis (LF) in mouse model. The present study aimed to evaluate the effects of other common oils on CCl 4 induced LF. Healthy male ICR mice were administered...

... cells through the Akt and ERK/miR-222/ETS-1 pathways. Our study provides experimental data that will aid the control of the process of fibrolysis in liver fibrosis prevention and treatment. 1 Correspondence may be addressed to either of these authors (email youhong30@sina.com or liu_tianhui...