1-14 of 14
Keywords: insulin secretion
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Biosci Rep (2018) 38 (2): BSR20170989.
Published: 21 March 2018
... with the plasma membrane. The mechanisms controlling these processes are complex and not fully understood but it is clear that the interaction of the β-cells with other β-cells in the islets is very important for their ability to develop the appropriate machinery for proper regulation of insulin secretion...
Biosci Rep (2006) 26 (1): 31–38.
Published: 15 June 2006
... and synthetic glucocorticoid are not beneficial to pancreatic β-cells in vitro. © 2006 Springer Science+Business Media, Inc. 2006 Dehydroepiandrosterone sulphate Dexamethasone Insulin secretion Glucose responsiveness Abbreviations DHEAS, Dehydroepiandrosterone sulphate; DEX, Dexamethasone...
Biosci Rep (2002) 22 (5-6): 523–528.
Published: 01 December 2002
...V.A. Gault; P. Harriott; P.R. Flatt; F.P.M. O'Harte Synthetic fragment peptides of glucose-dependent insulinotropic polypeptide (GIP) were evaluated for their ability to elevate cellular cAMP production and stimulate insulin secretion. In GIP receptor transfected CHL cells, GIP(4–42) and GIP(17–30...
Biosci Rep (2001) 21 (5): 653–666.
Published: 01 October 2001
... 2001 Plenum Publishing Corporation 2001 Insulin secretion pancreatic β-cell steroids membrane effects Bioscience Reports, Vol. 21, No. 5, October 2001 ( 2002) Progesterone Inhibits Insulin Secretion by a Membrane Delimited, Non-genomic Action Susanne G. Straub,1,4 Geoffrey W. G. Sharp,1...
Biosci Rep (2000) 20 (3): 167–176.
Published: 01 June 2000
... and pseudoislets in terms ofinsulin-secretory responses to glucose and amino acids. A 1.3-fold,2.2-fold and 1.7-fold stimulation of insulin secretion was observed forglucose, L-alanine and L-arginine respectively in single cellsuspensions. Corresponding increases for pseudoislets were1.6–1.8-fold for L-alanine...
Biosci Rep (1998) 18 (4): 171–186.
Published: 01 August 1998
... and Catalysis of Protein Phosphatase-2A in Insulin-Secreting Cells: Protection by Divalent Cations Anjaneyulu Kowluru1,3 and Stewart A. Metz2 Received March 25, 1998; accepted May 29, 1998 Recently, we demonstrated that the 36 kDa catalytic subunit of protein phosphatase 2A (PP2Ac) undergoes methylation at its...
Biosci Rep (1996) 16 (5): 415–423.
Published: 01 October 1996
... pancreatic islets enriched in β-cells were isolated and cultured for 3 days with or without 200 pM or 20 nM TGF-α. It was found that neither of these TGF-α concentrations affected β-cell mitogenesis, insulin content or insulin secretion. However, IFN-γ (1000 U/ml) evoked a modest stimulation of β-cell...
Biosci Rep (1996) 16 (1): 23–34.
Published: 01 February 1996
.... Emiglitate did not display any inhibitory action on insulin release induced by these secretagogues. Similarly, clonidine-induced inhibition of glucose stimulated insulin release was reversed by PTX. However, PTX did not influence the suppressive action of emiglitate on glucose-induced insulin secretion...
Biosci Rep (1993) 13 (6): 349–358.
Published: 01 December 1993
...Åke Sjöhom; Richard E. Honkanen; Per-Olof Berggren This study investigates the occurrence and regulation of serine/threonine protein phosphatases (PPases) in insulin-secreting RINm5F insulinoma cells. PPases types 1 and 2A were identified in crude RINm5F cell homogenates by both enzymatic assay...
Biosci Rep (1992) 12 (2): 95–100.
Published: 01 April 1992
...Nicholas S. Berrow; Roger D. Hurst; Susan L. F. Chan; Noel G. Morgan Rat islets express a pertussis toxin sensitive G-protein involved in receptor-mediated inhibition of insulin secretion. This has been assumed previously to represent “G i ” which couples inhibitory receptors to adenylate cyclase...
Biosci Rep (1991) 11 (3): 165–170.
Published: 01 June 1991
... Corporation 1991 17 5 1991 insulin secretion pancreatic islets coenzyme Q 0 quinone reductase insulin secretagogues quinones Bioscience Reports, Vol. I1, No. 3, 1991 Stimulation of Insulin Release from Pancreatic Islets by Quinones Michael J. MacDonald Received May 17, 1991 Coenzyme Q...
Biosci Rep (1989) 9 (2): 223–230.
Published: 01 April 1989
...Susan L. F. Chan; Noel G. Morgan In isolated rat islets the α 2 -adrenergic antagonist phenoxybenzamine was found to be only partially effective at relieving the inhibition of glucose-induced insulin secretion mediated by noradrenaline. Further experiment revealed a direct inhibitory effects...
Biosci Rep (1987) 7 (5): 443–454.
Published: 01 May 1987
...Claes B. Wollheim; Susanne Ullrich; Paolo Meda; Lucia Vallar The regulation of insulin secretion from RINm5F cells exposed to high voltage discharge has been investigated. Electron microscopy revealed that the overall structure of the cells was preserved after permeabilization. In this preparation...
Biosci Rep (1986) 6 (2): 163–169.
Published: 01 February 1986
...S. Lenzen; W. Schmidt; I. Rustenbeck; U. Panten The various neutral amino acids and aliphatic 2-keto acids exhibit differential effects on insulin secretion. The common denominator for all these effects is the 2-ketoglutarate generation in the pancreatic B-cell mitochondria. The neutral amino acids...