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Keywords: inflammation
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Articles
Biosci Rep (2022) 42 (9): BSR20211986.
Published: 05 September 2022
... Antigen presenting cell Graft-versus-host disease Inflammation Lymphocyte Xenogeneic graft-versus-host disease Graft-versus-host disease (GVHD) is an inflammatory disorder that can occur following allogeneic haematopoietic stem cell transplantation (HSCT) [ 1 , 2 ]. Allogeneic HSCT...
Articles
Biosci Rep (2022) 42 (7): BSR20212064.
Published: 18 July 2022
... , NFκB, P-STAT1 Y701 , STAT1, GAPDH protein involved in inflammation in mice spleen after LPS stimulating for 24 h. ( B ) A representative panel of immunohistochemical staining P-STAT1 Y701 on the spleen section. ( C ) Representative western blots analysis of P-AKT S473 , AKT, P-NFκB S536 , NFκB, P...
Includes: Supplementary data
Articles
Biosci Rep (2022) 42 (7): BSR20220251.
Published: 15 July 2022
...Victory Ibigo Poloamina; Wondwossen Abate; Gyorgy Fejer; Simon K. Jackson Inflammation is central to several diseases. TLR4 mediates inflammation by recognising and binding to bacterial lipopolysaccharides and interacting with other proteins in the TLR4 signalling pathway. Although...
Includes: Supplementary data
Articles
Biosci Rep (2022) 42 (2): BSR20212670.
Published: 07 February 2022
...Xiaoya Wang; Xinyu Zhang; Jianqing Su; Xiuling Chu Here, we study the therapeutic effect of Acanthopanax senticosus total flavonoids (ASTFs) using a mouse intestinal inflammation model. The inflammation model used in the present study was developed through lipopolysaccharide (LPS) treatment of mice...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (10): BSR-2020-2022_COR.
Published: 18 October 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . G. Oblongata red algae Natural products LPS Liver Kidney Inflammation...
Articles
Biosci Rep (2021) 41 (10): BSR20203573.
Published: 12 October 2021
... that thrombospondin-1 (TSP-1) is highly expressed in response to inflammation. In this work, we isolated and identified human thymic mesenchymal stromal cells (tMSCs) and detected the expression of TSP-1. We found that tMSCs expressed TSP-1 and Poly (I:C) or LPS treatment promoted the expression of TSP-1. Further, we...
Includes: Supplementary data
Articles
In Collection
Coronavirus
Biosci Rep (2021) 41 (7): BSR20210940.
Published: 22 July 2021
...-19) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) acute respiratory distress syndrome (ARDS) inflammation sTREM-1 mortality The current coronavirus disease 2019 (COVID-19) pandemic has, to date, led to almost three million deaths (World Health Organization [WHO...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (7): BSR20210954.
Published: 02 July 2021
...Rob G.H. Driessen; Dorien Kiers; Casper G. Schalkwijk; Jean L.J.M. Scheijen; Jelle Gerretsen; Peter Pickkers; Marcel C.G. van de Poll; Iwan C.C. van der Horst; Dennis C.J.J. Bergmans; Matthijs Kox; Bas C.T. van Bussel Background: Hypoxia and inflammation are hallmarks of critical illness, related...
Articles
Biosci Rep (2021) 41 (7): BSR-2019-2668_COR.
Published: 02 July 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . adiponectin human periodontal ligament cells inflammation...
Articles
Biosci Rep (2021) 41 (7): BSR20211066.
Published: 29 June 2021
... Of Auckland in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with CAUL. alpha catenin hexosamine biosynthesis pathway inflammation macrophages Macrophages are highly sensitive to environmental stimuli. To acquire...
Articles
Biosci Rep (2021) 41 (6): BSR20210736.
Published: 11 June 2021
...Maria E. Hammarlund; Vladimer Darsalia; Filip Mjörnstedt; Bagmi Pattanaik; Carina Mallard; Eridan Rocha-Ferreira; Cesare Patrone; Maria E. Johansson Inflammation plays a central role in stroke-induced brain injury. The alpha7 nicotinic acetylcholine receptor (α7nAChR) can modulate immune responses...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (6): BSR20203850.
Published: 11 June 2021
... to preserve intestinal homoeostasis, promote protective immune responses, and limit excessive inflammation. The importance of the microbiome is further highlighted during dysbiosis where a loss of this finely balanced microbial population can lead to mucosal barrier dysfunction, aberrant immune responses...
Articles
Biosci Rep (2021) 41 (5): BSR-20192668_EOC.
Published: 14 May 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . adiponectin human periodontal ligament cells inflammation...
Articles
Biosci Rep (2021) 41 (4): BSR-20192639_RET.
Published: 19 April 2021
..., alerting the authors to duplications in Figures 2C, 5A and 5C. This Retraction follows an Expression of Concern relating to this article previously published by Portland Press. acute lung injury apoptosis inflammation PPARγ PTEN/β-catenin pathway sepsis © 2021 The Author(s). 2021...
Articles
Biosci Rep (2021) 41 (4): BSR-20193419_EOC.
Published: 31 March 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . apoptosis inflammation miR-143-3p mycoplasmal pneumonia TLR4/MyD88/NF-κB...
Articles
Biosci Rep (2021) 41 (3): BSR20204247.
Published: 24 March 2021
... studies. The anti-asthma mechanism of ACG is associated with reduced airway inflammation and tracheal smooth muscle contraction, decreased eosinophil (EOS) number and serum LTE4 level, and recovery of the cAMP/cGMP balance [ 18 ]. However, the scientific basis and underlying pharmacological mechanism...
Includes: Supplementary data
Articles
Biosci Rep (2021) 41 (3): BSR20192668.
Published: 02 March 2021
...Huan-huan Wu; Yuan Guo; Yin-fei Pu; Zhi-hui Tang Periodontal diseases are infections of the structures that surround and support the teeth; they are characterized by local inflammation and alveolar bone loss. Most treatments focus on only one aspect, inhibiting inflammation, or promoting...
Articles
Biosci Rep (2021) 41 (1): BSR20202022.
Published: 15 January 2021
...Asmaa Nabil-Adam; Mohamed A. Shreadah Background: The liver and kidney inflammation due to bacterial infection is one of the most common pathological problems leading to tissue damage or disease. In many liver and kidney disorders, which represent serious global health burden with a high economic...
Articles
Biosci Rep (2020) 40 (12): BSR20201981.
Published: 21 December 2020
...Shunwan Jiang; Zhi Chen; Wenqiang Lai; Qingchun Mai; Dayu Chen; Shufen Sun; Yong Zhang Traditional Chinese medicine (TCM), such as Huanglian-Jie-Du-Tang, a heat-clearing and detoxifying decoction is beneficial for alleviation of inflammation-related diseases. The objective of the present study...
Articles
Biosci Rep (2020) 40 (11): BSR20203107.
Published: 23 November 2020
...Pengzhen Wang; Qingqi Meng; Wen Wang; Shaoheng Zhang; Xifeng Xiong; Shengnan Qin; Jinli Zhang; Aiguo Li; Zhihe Liu Articular cartilage injury or defect is a common disease and is mainly characterized by cartilage degradation because of chondrocyte inflammation. By now, there are no effective drugs...
Articles
Biosci Rep (2020) 40 (10): BSR20201098.
Published: 23 October 2020
... against this condition. The present study aims to investigate the protective effect of Zanthoxylum nitidum (ZN) on BMP-2-related hyperpermeability and inflammation on the human umbilical vein endothelial cells (HUVECs). The results revealed that, in a concentration-dependent manner, BMP-2 enhanced...
Articles
Biosci Rep (2020) 40 (9): BSR20201350.
Published: 24 September 2020
...&E, and finally observed under a microscope (BX51, Olympus, Japan). Breast cancer chemotherapy hematopoiesis inflammation low-intensity pulsed ultrasound myelosuppression Breast cancer is the most frequently diagnosed cancer in women worldwide and the leading cause of cancer-related...
Articles
Biosci Rep (2020) 40 (9): BSR20192910.
Published: 21 September 2020
... of inflammation and endothelial dysfunction markers among Egyptian females with different obesity classes. Methods: Out of 130 females, 70 were categorized into three obesity groups: Class I, body mass index (BMI) 30–34.9 kg/m 2 ; Class II, BMI 35–39.9 kg/m 2 and Class III BMI ≥ 40 kg/m 2 , besides 60 control...
Articles
Biosci Rep (2020) 40 (9): BSR20201885.
Published: 21 September 2020
...Hung-Ju Lin; Sung-Liang Yu; Ta-Chen Su; Hsiu-Ching Hsu; Ming-Fong Chen; Yuan-Teh Lee; Kuo-Liong Chien; Tzu-Pin Lu Statins inhibit cholesterol biogenesis and modulate atheroma inflammation to reduce cardiovascular risks. Promoted by immune and non-immune cells, serum C-reactive protein (CRP) might...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (9): BSR20192095.
Published: 16 September 2020
...-regulate EIF4G2 expression in chondrocytes, while miR-197 knockdown could elevate EIF4G2 expression. Additionally, EIF4G2 overexpression reversed the effects of miR-197 mimics on chondrocytes proliferation, migration, and inflammation. Taken together, our study demonstrated that miR-197 promotes...
Articles
Biosci Rep (2020) 40 (9): BSR-20190700_RET.
Published: 01 September 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Inflammation MicroRNA-142-3p Nuclear factor-kappa B Proliferation Tumor...
Articles
Biosci Rep (2020) 40 (8): BSR20201169.
Published: 20 August 2020
... published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . CXCL8 ERK Inflammation liver cancer malignant progression The human hepatoblastoma cell line HepG2 were provided by American type culture...
Articles
Biosci Rep (2020) 40 (7): BSR-20193431_COR.
Published: 30 July 2020
.... Data are presented as mean±SEM, n = 6, ### P <0.001 vs. the control group, ** P <0.01 and *** P <0.001 vs. the ox-LDL group. The original article “Naringin protects endothelial cells from apoptosis and inflammation by regulating the Hippo-YAP Pathway” ( Biosci Rep (2019) 40 (3...
Articles
Biosci Rep (2020) 40 (7): BSR20193419.
Published: 07 July 2020
... in mycoplasmal pneumonia mice by inhibiting TLR4/MyD88/NF-κB signaling pathway. apoptosis inflammation miR-143-3p mycoplasmal pneumonia TLR4/MyD88/NF-κB signaling pathway The whole blood samples of four mice in each group were centrifuged at 3500 rpm and 4°C for 15 min to obtain serum samples...
Articles
Biosci Rep (2020) 40 (7): BSR-20192536_COR.
Published: 03 July 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . biochemical haemolysis histology inflammation safety Surveillance...
Articles
Biosci Rep (2020) 40 (6): BSR-20190700_EOC.
Published: 25 June 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . MicroRNA-142-3p Inflammation Proliferation Tumor necrosis factor α...
Articles
Biosci Rep (2020) 40 (6): BSR-20192639_EOC.
Published: 24 June 2020
... inflammation The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. ...
Articles
Biosci Rep (2020) BSR20192842.
Published: 18 June 2020
... Commons licence. Curcumin Imiquimod Psoriasis IL-6 STAT3 Inflammation WITHDRAWN ARTICLE WITHDRAWN: Curcumin against imiquimod-induced psoriasis of mice through IL-6/STAT3 signaling pathway Yibin Zeng; Hongying Zhao; Tong Zhang; Chao Zhang; Yanni He; Lingbo Du; Fuguo Zuo; Wuqing Wang Biosci...
Articles
Biosci Rep (2020) 40 (6): BSR20194486.
Published: 17 June 2020
... BY) . inflammation lncRNA DILC neuropathic pain SOCS3 the JAK2/STAT3 pathway Neuropathic pain occurs from lesions or diseases affecting the somatosensory pathways within the peripheral or central nervous system (CNS). It is reported that neuropathic pain accounts for 7–8% prevalence among the general...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (6): BSR20200471.
Published: 17 June 2020
...) and MAPK (JNK, ERK, and p38) signaling pathways. Similar alterations for oxidative stress and inflammation parameters were also detected in TNF-α-treated HaCaT cells. In addition, cimifugin-induced down-regulation of ICAM-1 were observed in TNF-α-treated cells. Altogether, our findings suggest...
Articles
Biosci Rep (2020) 40 (6): BSR20192536.
Published: 05 June 2020
.... The lungs showed alveolar with evidence of inflammation and foci of epithelial sloughing. Alveolar spaces were also obscured by debris and inflammatory cells. HPA and HPC produced scattered intensely congested heart vessels while HPB(10) produced haemorrhage and amorphous exudates within the heart. All HMPs...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (5): BSR20192110.
Published: 29 May 2020
...Narisara Paradee; Niramon Utama-ang; Chairat Uthaipibull; John B. Porter; Maciej W. Garbowski; Somdet Srichairatanakool Elevation of endothelial microparticles (EMPs) play an important role in the progression of inflammation-related vascular diseases such as cardiovascular diseases (CVDs). Thai...
Articles
Biosci Rep (2020) 40 (5): BSR20194345.
Published: 28 May 2020
... Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . acute pancreatitis diagnosis inflammation microRNA-192-5p nonalcoholic fatty liver disease proliferation Acute pancreatitis (AP) is an inflammatory disease...
Articles
Biosci Rep (2020) 40 (5): BSR20192639.
Published: 28 May 2020
.... Compared with Sham group, the mRNA and protein expression levels of PPARγ were down-regulated, the inflammation levels were elevated, and the apoptosis was increased in CLP group. After treatment with rosiglitazone, the protein expression level of PPARγ was significantly up-regulated, the phosphorylation...
Articles
Biosci Rep (2020) 40 (5): BSR20200417.
Published: 28 May 2020
... lipopolysaccharide (LPS) for 12 h. Then, pcDNA3.1-Per2 and si-Per2 were recruited to boost and reduce the expression of Per2, respectively. MTT assay, apoptosis analysis and enzyme-linked immunosorbent assay (ELISA) results showed that Per2 increased cell proliferation, while inhibited apoptosis and inflammation...
Articles
Biosci Rep (2020) 40 (5): BSR20192132.
Published: 27 May 2020
... (miR-124-3p) helps to suppress inflammation during a pulmonary injury. However, its mechanism of action is largely unknown, and its role in ARDS remains to be determined. Methods: Mice and NR8383 cells were exposed to lipopolysaccharides (LPS) to induce ARDS, and their miR-124-3p levels were determined...
Articles
Biosci Rep (2020) 40 (4): BSR20193653.
Published: 29 April 2020
..., TIMP3 was a target of miR-770-5p in HG-treated podocytes. TIMP3 inhibited cell apoptosis and inflammation in HG-treated podocytes. Moreover, TIMP3 knockdown alleviated the inhibitory effect of miR-770-5p silencing on podocyte apoptosis and inflammatory response. Conclusion: Knockdown of miR-770-5p...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (4): BSR20192133.
Published: 15 April 2020
... and cleaved caspase-3 expression, and up-regulate Bcl-Xl expression. Conclusion: Stigmasterol protects the brain from brain I/R damage by reducing oxidative stress and inflammation. The TUNEL staining was used to detect cell apoptosis on the basis of DNA fragmentation that results from the apoptosis...
Articles
Biosci Rep (2020) 40 (3): BSR20194296.
Published: 27 March 2020
... nanoparticles histopathology inflammation performance Nanotechnology is defined as the comprehension and control of matter at the nano scale, at measurements between roughly 1 and 100 nanometers [ 1 , 2 ]. In the ongoing years, nanotechnology had been advance and had the most impact on all parts...
Articles
Biosci Rep (2020) 40 (3): BSR20194188.
Published: 04 March 2020
... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . ALK5 foam cell inflammation KLF4 macrophage Atherosclerosis is well recognized as a chronic inflammatory disease...
Articles
Biosci Rep (2020) 40 (3): BSR20193431.
Published: 04 March 2020
...Hui Zhao; Meirong Liu; Hui Liu; Rong Suo; Chengzhi Lu Atherosclerosis is the primary cause of several cardiovascular diseases. Oxidized low-density lipoprotein (ox-LDL)-induced apoptosis, endothelial–mesenchymal transition (EndMT), and inflammation are crucial for the progression of cardiovascular...
Articles
Biosci Rep (2020) 40 (2): BSR20193101.
Published: 24 February 2020
... receptor related protein; GO-BP, Gene Ontology Biological Process; KEGG, Kyoto Encyclopedia of Genes and Genomes. antibody array bioinformatics analysis chronic rhinosinusitis with nasal polyposis endotype eosinophil inflammation Chronic rhinosinusitis with nasal polyposis (CRSwNP...
Includes: Supplementary data
Articles
Biosci Rep (2020) 40 (2): BSR20194230.
Published: 14 February 2020
.... Nevertheless, the mechanism of the potential anti-inflammatory effects of SOG is unclear. The anti-inflammatory impacts of SOG in RAW 264.7 cell lines stimulated by LPS were explored in the present study. It was found that SOG dose-dependently reduced the emergence of inflammation cytokines, such as IL-6...
Articles
Biosci Rep (2020) 40 (2): BSR20194208.
Published: 04 February 2020
....). © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . inflammation inflammatory pain PTX3 TLR4/NF-κB axis Inflammatory pain...
Articles
Biosci Rep (2020) 40 (1): BSR20191043.
Published: 24 January 2020
..., a proven antioxidant, has been shown to protect tissue by antioxidation and anti-inflammation in clinic [ 5 ], as well as in various animal models of I/R [ 6 , 7 ], including intestinal I/R [ 8 ]. Such hydrogen-rich saline (HRS), by selectively reacting with hydroxyl radicals and peroxynitrite, the most...
Includes: Supplementary data