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Keywords: hypertension
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Biosci Rep (2022) 42 (11): BSR20220285.
Published: 23 November 2022
... further studies. In this sense, the present study aims to review the current knowledge on venous endothelial function and dysfunction, and the general state of the venous tone in two important cardiovascular diseases of high incidence and morbimortality worldwide: hypertension and heart failure...
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Biosci Rep (2021) 41 (12): BSR20211201.
Published: 07 December 2021
... are associated with ACE/ACE2 imbalance in the lungs. Experiments were conducted in male and female Wistar rats and spontaneously hypertensive rats (SHRs). Lung ACE and ACE2 gene expression was also evaluated in normotensive and hypertensive humans using the Genotype-Tissue Expression (GTEx) project. Compared...
Includes: Supplementary data
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Biosci Rep (2021) 41 (5): BSR20210029.
Published: 14 May 2021
... 04 2021 © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . ADAM17 hypertension metabolic syndromes obesity TACE type 2...
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Biosci Rep (2019) 39 (1): BSR20180201.
Published: 11 January 2019
... therapeutic approach. The scope of the research findings not only opens doors for potentially new therapeutics of hypertension and many other diseases, but also provides insights into understanding critical physiological and pathophysiological roles mediated by AGT. Correspondence: Hong S. Lu ( Hong.Lu...
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Biosci Rep (2018) 38 (4): BSR20180525.
Published: 29 August 2018
...Xiaoyi Zhang; Xiaoyan Wang; Jian Wu; Juan Peng; Xin Deng; Yi Shen; Chunjie Yang; Jie Yuan; Yunzeng Zou Few studies have compared the performances of those reported miRNAs as biomarkers for hypertension in a same cohort, we aimed to comprehensively examine the performances of those reported miRNAs...
Includes: Supplementary data
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Biosci Rep (2018) 38 (4): BSR20180111.
Published: 03 July 2018
...Ellen E. Gillis; Krystal N. Brinson; Olga Rafikova; Wei Chen; Jacqueline B. Musall; David G. Harrison; Jennifer C. Sullivan We previously published that female spontaneously hypertensive rats (SHR) have significantly greater nitric oxide (NO) bioavailability and NO synthase (NOS) enzymatic activity...
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Biosci Rep (2015) 35 (3): e00217.
Published: 22 June 2015
...Qingbin Zhao; Junfang Zhang; Huifang Wang Increasing evidences have accumulated that endothelial dysfunction is involved in the pathogenesis of hypertension. Peroxisome proliferator-activated receptor γ (PPARγ) coactivator-1α (PGC-1α) has been identified as an essential factor that protects against...
Includes: Supplementary data
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Biosci Rep (2014) 34 (3): e00107.
Published: 09 May 2014
...Daiei Takahashi; Takayasu Mori; Naohiro Nomura; Muhammad Zakir Hossain Khan; Yuya Araki; Moko Zeniya; Eisei Sohara; Tatemitsu Rai; Sei Sasaki; Shinichi Uchida By analysing the pathogenesis of a hereditary hypertensive disease, PHAII (pseudohypoaldosteronism type II), we previously discovered...
Includes: Supplementary data
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