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Keywords: hepatocellular carcinoma
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Articles

Identification of PPT1 as a lysosomal core gene with prognostic value in hepatocellular carcinoma

Wei Tian, Chenyu Li, Jiaqi Ren, Pengfei Li, Jingyuan Zhao, Shuai Li, Deshi Dong
Journal: Bioscience Reports
Biosci Rep (2023) 43 (5): BSR20230067.
DOI: https://doi.org/10.1042/BSR20230067
Published: 18 May 2023
...Wei Tian; Chenyu Li; Jiaqi Ren; Pengfei Li; Jingyuan Zhao; Shuai Li; Deshi Dong Hepatocellular carcinoma (HCC) is the most frequent cancer worldwide with a poor prognosis. Unfortunately, there are few reports on effective biomarkers for HCC, identification of novel cancer targets is urgently needed...
View article titled, Identification of PPT1 as a lysosomal core gene with prognostic value in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Identification of PPT1 as a lysosomal core gene with prognostic value in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Includes: Supplementary data
Articles

Prognostic value of the S100 calcium binding protein family members in hepatocellular carcinoma

Ran Wei, Ou qi feng, Yao ze hui, Xiaohui Huang, Li sheng ping
Journal: Bioscience Reports
Biosci Rep (2023) BSR20222523.
DOI: https://doi.org/10.1042/BSR20222523
Published: 03 May 2023
...Ran Wei; Ou qi feng; Yao ze hui; Xiaohui Huang; Li sheng ping Hepatocellular carcinoma (HCC) remains a crucial public health problem around the world, and the outlook remains bleak. More accurate prediction models are urgently needed because of the great heterogeneity of HCC. The S100 protein...
View article titled, Prognostic value of the S100 calcium binding protein family members in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Prognostic value of the S100 calcium binding protein family members in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Articles

Inflammatory processes involved in NASH-related hepatocellular carcinoma

Stefania Cannito, Umberto Dianzani, Maurizio Parola, Emanuele Albano, Salvatore Sutti
Journal: Bioscience Reports
Biosci Rep (2023) 43 (1): BSR20221271.
DOI: https://doi.org/10.1042/BSR20221271
Published: 24 January 2023
...Stefania Cannito; Umberto Dianzani; Maurizio Parola; Emanuele Albano; Salvatore Sutti Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related death worldwide. In the recent years nonalcoholic fatty liver disease (NAFLD) is becoming a growing cause of HCCs and the incidence...
View article titled, Inflammatory processes involved in NASH-related <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Inflammatory processes involved in NASH-related <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Articles

INK4 cyclin-dependent kinase inhibitors as potential prognostic biomarkers and therapeutic targets in hepatocellular carcinoma

Hui Liu, Songhao Jia, Kun Guo, Rongkuan Li
Journal: Bioscience Reports
Biosci Rep (2022) 42 (7): BSR20221082.
DOI: https://doi.org/10.1042/BSR20221082
Published: 14 July 2022
...Hui Liu; Songhao Jia; Kun Guo; Rongkuan Li The INK4 family is an important family of cyclin-dependent kinase inhibitors (CDKIs) and consists of CDKN2A, CDKN2B, CDKN2, and CDKN2D. Abnormal expression of CDKN2A has been reported in hepatocellular carcinoma (HCC) and is associated with the prognosis...
View article titled, INK4 cyclin-dependent kinase inhibitors as potential prognostic biomarkers and therapeutic targets in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for INK4 cyclin-dependent kinase inhibitors as potential prognostic biomarkers and therapeutic targets in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Includes: Supplementary data
Articles

Retraction: Exosomes function as nanoparticles to transfer miR-199a-3p to reverse chemoresistance to cisplatin in hepatocellular carcinoma

Journal: Bioscience Reports
Biosci Rep (2022) 42 (6): BSR-2019-4026_RET.
DOI: https://doi.org/10.1042/BSR-2019-4026_RET
Published: 27 June 2022
... DDP Exosome hepatocellular carcinoma Huh-7/DDP miR-199a-3p This Retraction follows an Expression of Concern relating to this article previously published by Portland Press. This article is being retracted from Bioscience Reports at the request of the authors following receipt...
View article titled, Retraction: Exosomes function as nanoparticles to transfer miR-199a-3p to reverse chemoresistance to cisplatin in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Retraction: Exosomes function as nanoparticles to transfer miR-199a-3p to reverse chemoresistance to cisplatin in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Articles

Expression of Concern: Exosomes function as nanoparticles to transfer miR-199a-3p to reverse chemoresistance to cisplatin in hepatocellular carcinoma

Journal: Bioscience Reports
Biosci Rep (2022) 42 (6): BSR-2019-4026_EOC.
DOI: https://doi.org/10.1042/BSR-2019-4026_EOC
Published: 14 June 2022
... © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . DDP Exosome hepatocellular carcinoma Huh-7/DDP miR-199a-3p...
View article titled, Expression of Concern: Exosomes function as nanoparticles to transfer miR-199a-3p to reverse chemoresistance to cisplatin in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Expression of Concern: Exosomes function as nanoparticles to transfer miR-199a-3p to reverse chemoresistance to cisplatin in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Articles

Single-cell transcriptomics analysis reveals intratumoral heterogeneity and identifies a gene signature associated with prognosis of hepatocellular carcinoma

Jialu Liang, Wenhui Chen, Jianwen Ye, Chen Ni, Wenlong Zhai
Journal: Bioscience Reports
Biosci Rep (2022) 42 (2): BSR20212560.
DOI: https://doi.org/10.1042/BSR20212560
Published: 25 February 2022
...Jialu Liang; Wenhui Chen; Jianwen Ye; Chen Ni; Wenlong Zhai Hepatocellular carcinoma (HCC) tumors exhibit high heterogeneity. However, current understanding of tumor cell heterogeneity of HCC and the association with prognosis remains very limited. In the present study, we collected and examined...
View article titled, Single-cell transcriptomics analysis reveals intratumoral heterogeneity and identifies a gene signature associated with prognosis of <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Single-cell transcriptomics analysis reveals intratumoral heterogeneity and identifies a gene signature associated with prognosis of <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Includes: Supplementary data
Articles

Current progress of immune checkpoint inhibitors in the treatment of advanced hepatocellular carcinoma

Xiaoqiang Yin, Tongchui Wu, Yadong Lan, Wulin Yang
Journal: Bioscience Reports
Biosci Rep (2022) 42 (2): BSR20212304.
DOI: https://doi.org/10.1042/BSR20212304
Published: 07 February 2022
...Xiaoqiang Yin; Tongchui Wu; Yadong Lan; Wulin Yang Hepatocellular carcinoma (HCC) is the most common primary liver cancer worldwide. The onset of the disease is occult and develops rapidly. As a result, the disease is often detected when it is already in advanced stages, resulting in patients...
View article titled, Current progress of immune checkpoint inhibitors in the treatment of advanced <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
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Articles

Correction: CDKN2A is a prognostic biomarker and correlated with immune infiltrates in hepatocellular carcinoma

Journal: Bioscience Reports
Biosci Rep (2022) 42 (1): BSR-2021-1103_COR.
DOI: https://doi.org/10.1042/BSR-2021-1103_COR
Published: 06 January 2022
... © 2022 The Author(s). 2022 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . CDKN2A Hepatocellular carcinoma Immune signature Prognostic biomarker...
View article titled, Correction: CDKN2A is a prognostic biomarker and correlated with immune infiltrates in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
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Articles

Bioinformatics analysis of tumor-educated platelet microRNAs in patients with hepatocellular carcinoma

Beibei Zhu, Shanshan Gu, Xiaoting Wu, Wenyong He, Hongke Zhou
Journal: Bioscience Reports
Biosci Rep (2021) 41 (12): BSR20211420.
DOI: https://doi.org/10.1042/BSR20211420
Published: 08 December 2021
...Beibei Zhu; Shanshan Gu; Xiaoting Wu; Wenyong He; Hongke Zhou Background: Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies that seriously threaten global health. The primary reason for its grim prognosis is the lack of sensitive tools for early diagnosis. The purpose...
View article titled, Bioinformatics analysis of tumor-educated platelet microRNAs in patients with <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
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Includes: Supplementary data
Articles

CDKN2A is a prognostic biomarker and correlated with immune infiltrates in hepatocellular carcinoma

Jun-peng Luo, Jing Wang, Jin-hua Huang
Journal: Bioscience Reports
Biosci Rep (2021) 41 (10): BSR20211103.
DOI: https://doi.org/10.1042/BSR20211103
Published: 06 October 2021
...Jun-peng Luo; Jing Wang; Jin-hua Huang Cyclin dependent kinase inhibitor 2A (CDKN2A) is an essential regulator of immune cell functionality, but the mechanisms whereby it drives immune infiltration in hepatocellular carcinoma (HCC) remain unclear. In the present study, we studied the association...
View article titled, CDKN2A is a prognostic biomarker and correlated with immune infiltrates in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
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Articles

Development and validation of LRP1B mutation-associated prognostic model for hepatocellular carcinoma

Jian Xu, Xiaomin Shen, Bo Zhang, Rui Su, Mingxuan Cui, Lihua Yan, Yu Cao
Journal: Bioscience Reports
Biosci Rep (2021) 41 (9): BSR20211053.
DOI: https://doi.org/10.1042/BSR20211053
Published: 31 August 2021
...Jian Xu; Xiaomin Shen; Bo Zhang; Rui Su; Mingxuan Cui; Lihua Yan; Yu Cao Purpose: To develop a lipoprotein receptor-related protein 1B ( LRP1B ) gene mutation-based prognostic model for hepatocellular carcinoma (HCC) patients risk prediction. Methods: The LRP1B gene mutation rate was calculated...
View article titled, Development and validation of LRP1B mutation-associated prognostic model for <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Development and validation of LRP1B mutation-associated prognostic model for <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Includes: Supplementary data
Articles

Retraction: Effects of LncRNA-HOST2 on cell proliferation, migration, invasion and apoptosis of human hepatocellular carcinoma cell line SMMC-7721

Journal: Bioscience Reports
Biosci Rep (2021) 41 (8): BSR-2016-0532_RET.
DOI: https://doi.org/10.1042/BSR-2016-0532_RET
Published: 24 August 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Hepatocellular carcinoma Human ovarian cancer specific transcript 2 Long...
View article titled, Retraction: Effects of LncRNA-HOST2 on cell proliferation, migration, invasion and apoptosis of human <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cell line SMMC-7721
Click here to open pdf in another window PDF for Retraction: Effects of LncRNA-HOST2 on cell proliferation, migration, invasion and apoptosis of human <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cell line SMMC-7721
Articles

A new discovery of STAT4 single nucleotide polymorphisms associated with hepatocellular carcinoma risk in Chinese Han population: a case–control study

Xu Chao, Jieqiong Wu, Wei Zhang, Xuesong Feng, Luyan Zhao, Feng Huang, Chao Jiang
Journal: Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20210124.
DOI: https://doi.org/10.1042/BSR20210124
Published: 26 July 2021
...Xu Chao; Jieqiong Wu; Wei Zhang; Xuesong Feng; Luyan Zhao; Feng Huang; Chao Jiang Background: Hepatocellular carcinoma (HCC) is a common fatal malignant tumor worldwide. Signal transducer and activator of transcription 4 (STAT4) is HCC susceptibility gene identified by genome-wide association study...
View article titled, A new discovery of STAT4 single nucleotide polymorphisms associated with <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> risk in Chinese Han population: a case–control study
Click here to open pdf in another window PDF for A new discovery of STAT4 single nucleotide polymorphisms associated with <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> risk in Chinese Han population: a case–control study
Articles

Evaluation of anticancer effects of Juniperus communis extract on hepatocellular carcinoma cells in vitro and in vivo

Nan-Chieh Huang, Ru-Lai Huang, Xiao-Fan Huang, Kai-Fu Chang, Chien-Ju Lee, Chih-Yen Hsiao, Shan-Chih Lee, Nu-Man Tsai
Journal: Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20211143.
DOI: https://doi.org/10.1042/BSR20211143
Published: 12 July 2021
...Nan-Chieh Huang; Ru-Lai Huang; Xiao-Fan Huang; Kai-Fu Chang; Chien-Ju Lee; Chih-Yen Hsiao; Shan-Chih Lee; Nu-Man Tsai Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and accounts for the fourth leading cause of all cancer deaths. Scientific evidence has found...
View article titled, Evaluation of anticancer effects of Juniperus communis extract on <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cells in vitro and in vivo
Click here to open pdf in another window PDF for Evaluation of anticancer effects of Juniperus communis extract on <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cells in vitro and in vivo
Articles

Multi-omic analyses of hepatocellular carcinoma to determine immunological characteristics and key nodes in gene-expression network

Zhihui Wang, Shuijun Zhang
Journal: Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20211241.
DOI: https://doi.org/10.1042/BSR20211241
Published: 12 July 2021
...Zhihui Wang; Shuijun Zhang Hepatocellular carcinoma (HCC) is a common malignant tumor worldwide, but effective immunotherapy is still limited for those affected. Therefore, there is an urgent need to explore the specific mechanisms governing tumor immunity to improve the survival rate for those...
View article titled, Multi-omic analyses of <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> to determine immunological characteristics and key nodes in gene-expression network
Click here to open pdf in another window PDF for Multi-omic analyses of <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> to determine immunological characteristics and key nodes in gene-expression network
Includes: Supplementary data
Articles

Integrated bioinformatics analysis revealed the regulation of angiogenesis by tumor cells in hepatocellular carcinoma

Meisi Huo, Kangkang Yu, Yahui Zheng, Lu Liu, Hao Zhao, Xiaoqi Li, Chong Huang, Jubo Zhang
Journal: Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20210126.
DOI: https://doi.org/10.1042/BSR20210126
Published: 01 July 2021
...Meisi Huo; Kangkang Yu; Yahui Zheng; Lu Liu; Hao Zhao; Xiaoqi Li; Chong Huang; Jubo Zhang Hepatocellular carcinoma (HCC) is one of the leading causes of cancer mortality, metastasis accounts for most of the cases. Angiogenesis plays an important role in cancer metastasis, but how tumor cells affect...
View article titled, Integrated bioinformatics analysis revealed the regulation of angiogenesis by tumor cells in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Integrated bioinformatics analysis revealed the regulation of angiogenesis by tumor cells in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Includes: Supplementary data
Articles

CXCL2/10/12/14 are prognostic biomarkers and correlated with immune infiltration in hepatocellular carcinoma

Tong Lin, E Zhang, Pei-pei Mai, Ying-zhao Zhang, Xiang Chen, Li-sheng Peng
Journal: Bioscience Reports
Biosci Rep (2021) 41 (6): BSR20204312.
DOI: https://doi.org/10.1042/BSR20204312
Published: 18 June 2021
... infiltration of hepatocellular carcinoma (HCC) patients is unclear yet. Methods: Differentially expressed CXCLs between HCC and normal control were screened by Oncomine and GEPIA2. Genetic alternations of CXCLs in HCC were analyzed by cBioPortal. Clinicopathological relevance of CXCLs in HCC patients...
View article titled, CXCL2&#x2F;10&#x2F;12&#x2F;14 are prognostic biomarkers and correlated with immune infiltration in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for CXCL2/10/12/14 are prognostic biomarkers and correlated with immune infiltration in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Articles

Identification of m6A methyltransferase-related lncRNA signature for predicting immunotherapy and prognosis in patients with hepatocellular carcinoma

Lili Li, Rongrong Xie, Guangrong Lu
Journal: Bioscience Reports
Biosci Rep (2021) 41 (6): BSR20210760.
DOI: https://doi.org/10.1042/BSR20210760
Published: 08 June 2021
...Lili Li; Rongrong Xie; Guangrong Lu N6-methyladenosine (m6A) methyltransferase has been shown to be an oncogene in a variety of cancers. Nevertheless, the relationship between the long non-coding RNAs (lncRNAs) and hepatocellular carcinoma (HCC) remains elusive. We integrated the gene expression...
View article titled, Identification of m6A methyltransferase-related lncRNA signature for predicting immunotherapy and prognosis in patients with <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Identification of m6A methyltransferase-related lncRNA signature for predicting immunotherapy and prognosis in patients with <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Includes: Supplementary data
Articles

Identification and validation of ADME genes as prognosis and therapy markers for hepatocellular carcinoma patients

Jukun Wang, Ke Han, Chao Zhang, Xin Chen, Yu Li, Linzhong Zhu, Tao Luo
Journal: Bioscience Reports
Biosci Rep (2021) 41 (5): BSR20210583.
DOI: https://doi.org/10.1042/BSR20210583
Published: 27 May 2021
... the predictive ability of the prediction model. Hepatocellular carcinoma prognosis signature TCGA Hepatocellular carcinoma (HCC) is the most common liver cancer type [ 1 ]. It is the sixth-leading cause of cancer morbidity and fourth cause of cancer mortality worldwide [ 2 , 3 ]. The main risk...
View article titled, Identification and validation of ADME genes as prognosis and therapy markers for <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> patients
Click here to open pdf in another window PDF for Identification and validation of ADME genes as prognosis and therapy markers for <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> patients
Articles

Down-regulation of RBP4 indicates a poor prognosis and correlates with immune cell infiltration in hepatocellular carcinoma

Mingxing Li, Zhihui Wang, Lixu Zhu, Yifang Shui, Shuijun Zhang, Wenzhi Guo
Journal: Bioscience Reports
Biosci Rep (2021) 41 (4): BSR20210328.
DOI: https://doi.org/10.1042/BSR20210328
Published: 16 April 2021
...Mingxing Li; Zhihui Wang; Lixu Zhu; Yifang Shui; Shuijun Zhang; Wenzhi Guo Recent research has indicated that metabolically related genes play crucial roles in the pathogenesis of hepatocellular carcinoma (HCC). We evaluated the associations between novel biomarkers and retinol-binding protein 4...
View article titled, Down-regulation of RBP4 indicates a poor prognosis and correlates with immune cell infiltration in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Down-regulation of RBP4 indicates a poor prognosis and correlates with immune cell infiltration in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Articles

A dual immune signature of CD8+ T cells and MMP9 improves the survival of patients with hepatocellular carcinoma

Huan Ding, Huan Hu, Feifei Tian, Huaping Liang
Journal: Bioscience Reports
Biosci Rep (2021) 41 (3): BSR20204219.
DOI: https://doi.org/10.1042/BSR20204219
Published: 17 March 2021
...Huan Ding; Huan Hu; Feifei Tian; Huaping Liang The 5-year survival of hepatocellular carcinoma (HCC) is difficult due to the high recurrence rate and metastasis. Tumor infiltrating immune cells (TICs) and immune-related genes (IRGs) bring hope to improve survival and treatment of HCC patients...
View article titled, A dual immune signature of CD8+ T cells and MMP9 improves the survival of patients with <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for A dual immune signature of CD8+ T cells and MMP9 improves the survival of patients with <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Includes: Supplementary data
Articles

The relationship among Girdin DNA methylation, its high expression, and immune infiltration in hepatocellular carcinoma: Clues from in silico analysis

Cheng Zhang, Yang Ke, Xuefen Lei, Xin Liu, Hai Li, Runjiao Shi, Lin Wang
Journal: Bioscience Reports
Biosci Rep (2021) 41 (3): BSR20204006.
DOI: https://doi.org/10.1042/BSR20204006
Published: 15 March 2021
...Cheng Zhang; Yang Ke; Xuefen Lei; Xin Liu; Hai Li; Runjiao Shi; Lin Wang Objective: The aim of the present study was to explore the relationship among Girdin DNA methylation, its high expression, and immune infiltration in human hepatocellular carcinoma (HCC). Materials and methods: The Cancer...
View article titled, The relationship among Girdin DNA methylation, its high expression, and immune infiltration in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>: Clues from in silico analysis
Click here to open pdf in another window PDF for The relationship among Girdin DNA methylation, its high expression, and immune infiltration in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>: Clues from in silico analysis
Includes: Supplementary data
Articles

A novel DNA methylation-based model that effectively predicts prognosis in hepatocellular carcinoma

Xiang-Yong Hao, An-Qiang Li, Hao Shi, Tian-Kang Guo, Yan-Fei Shen, Yuan Deng, Li-Tian Wang, Tao Wang, Hui Cai
Journal: Bioscience Reports
Biosci Rep (2021) 41 (3): BSR20203945.
DOI: https://doi.org/10.1042/BSR20203945
Published: 10 March 2021
...Xiang-Yong Hao; An-Qiang Li; Hao Shi; Tian-Kang Guo; Yan-Fei Shen; Yuan Deng; Li-Tian Wang; Tao Wang; Hui Cai Purpose: To build a novel predictive model for hepatocellular carcinoma (HCC) patients based on DNA methylation data. Methods: Four independent DNA methylation datasets for HCC were used...
View article titled, A novel DNA methylation-based model that effectively predicts prognosis in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for A novel DNA methylation-based model that effectively predicts prognosis in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Includes: Supplementary data
Articles

Integrated bioinformatics analysis identified MTHFD1L as a potential biomarker and correlated with immune infiltrates in hepatocellular carcinoma

Junhui Chen, Jie Yang, Qingchun Xu, Zhenyu Wang, Jun Wu, Liukui Pan, Kai Huang, Chen Wang
Journal: Bioscience Reports
Biosci Rep (2021) 41 (2): BSR20202063.
DOI: https://doi.org/10.1042/BSR20202063
Published: 19 February 2021
...Junhui Chen; Jie Yang; Qingchun Xu; Zhenyu Wang; Jun Wu; Liukui Pan; Kai Huang; Chen Wang Liver hepatocellular carcinoma (LIHC) is one of the most frequently occurring primary malignant liver tumors and seriously harms people’s health in the world. Methylenetetrahydrofolate dehydrogenase 1-like...
View article titled, Integrated bioinformatics analysis identified MTHFD1L as a potential biomarker and correlated with immune infiltrates in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
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Articles

Identification of an autophagy-related gene signature predicting overall survival for hepatocellular carcinoma

Wenfang Xu, Wenke Guo, Ping Lu, Duan Ma, Lei Liu, Fudong Yu
Journal: Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203231.
DOI: https://doi.org/10.1042/BSR20203231
Published: 15 January 2021
...Wenfang Xu; Wenke Guo; Ping Lu; Duan Ma; Lei Liu; Fudong Yu The poor prognosis of hepatocellular carcinoma (HCC) calls for the development of accurate prognostic models. The growing number of studies indicating a correlation between autophagy activity and HCC indicates there is a commitment...
View article titled, Identification of an autophagy-related gene signature predicting overall survival for <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
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Articles

Elevated CDK5R1 predicts worse prognosis in hepatocellular carcinoma based on TCGA data

Zhili Zeng, Zebiao Cao, Enxin Zhang, Haifu Huang, Ying Tang
Journal: Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203594.
DOI: https://doi.org/10.1042/BSR20203594
Published: 07 January 2021
...Zhili Zeng; Zebiao Cao; Enxin Zhang; Haifu Huang; Ying Tang Background: Hepatocellular carcinoma (HCC) is a malignant tumor with rapid progression, high recurrence rate and poor prognosis. The objective of our investigation was to explore the prognostic value of CDK5R1 in HCC. Methods: The raw data...
View article titled, Elevated CDK5R1 predicts worse prognosis in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> based on TCGA data
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Articles

FAM225A promotes sorafenib resistance in hepatocarcinoma cells through modulating miR-130a-5p–CCNG1 interaction network

Yan-Tong Liu, Guo-Qing Liu, Jing-Min Huang
Journal: Bioscience Reports
Biosci Rep (2020) 40 (12): BSR20202054.
DOI: https://doi.org/10.1042/BSR20202054
Published: 16 December 2020
...Yan-Tong Liu; Guo-Qing Liu; Jing-Min Huang Chemotherapy resistance is still a key hurdle in current hepatocellular carcinoma (HCC) treatment. Therefore, clarifying the molecular mechanisms contributing to this acquired resistance is urgent for the effective treatment of liver cancer...
View article titled, FAM225A promotes sorafenib resistance in hepatocarcinoma cells through modulating miR-130a-5p–CCNG1 interaction network
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Articles

Exploration and validation of a novel prognostic signature based on comprehensive bioinformatics analysis in hepatocellular carcinoma

Xiaofei Wang, Jie Qiao, Rongqi Wang
Journal: Bioscience Reports
Biosci Rep (2020) 40 (11): BSR20203263.
DOI: https://doi.org/10.1042/BSR20203263
Published: 13 November 2020
...Xiaofei Wang; Jie Qiao; Rongqi Wang The present study aimed to construct a novel signature for indicating the prognostic outcomes of hepatocellular carcinoma (HCC). Gene expression profiles were downloaded from Gene Expression Omnibus (GEO), The Cancer Genome Atlas (TCGA) and the International...
View article titled, Exploration and validation of a novel prognostic signature based on comprehensive bioinformatics analysis in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
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Articles

MicroRNA-183-5p contributes to malignant progression through targeting PDCD4 in human hepatocellular carcinoma

Xiaohui Duan, Wei Li, Peng Hu, Bo Jiang, Jianhui Yang, Lixue Zhou, Xianhai Mao, Bingzhang Tian
Journal: Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20201761.
DOI: https://doi.org/10.1042/BSR20201761
Published: 30 October 2020
...Xiaohui Duan; Wei Li; Peng Hu; Bo Jiang; Jianhui Yang; Lixue Zhou; Xianhai Mao; Bingzhang Tian Hepatocellular carcinoma (HCC) remains one of the most common malignant tumors worldwide. The present study aimed to investigate the biological role of microRNA-183-5p (miR-183-5p), a novel tumor-related...
View article titled, MicroRNA-183-5p contributes to malignant progression through targeting PDCD4 in human <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
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Articles

Identification of prognostic biomarkers and correlations with immune infiltrates among cGAS-STING in hepatocellular carcinoma

Zhenhua Qi, Fang Yan, Dongtai Chen, Wei Xing, Qiang Li, Weian Zeng, Bingtian Bi, Jingdun Xie
Journal: Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20202603.
DOI: https://doi.org/10.1042/BSR20202603
Published: 16 October 2020
... revealed that self-DNA from by-products of chromosome instability and tumors could activate the cGAS-STING pathway, and subsequently promote or inhibit tumor development. However, the prognostic value and correlations with immune infiltrates of the cGAS-STING pathway in hepatocellular carcinoma (HCC) have...
View article titled, Identification of prognostic biomarkers and correlations with immune infiltrates among cGAS-STING in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Identification of prognostic biomarkers and correlations with immune infiltrates among cGAS-STING in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Includes: Supplementary data
Articles

Prognostic value of aberrantly expressed methylation genes in human hepatocellular carcinoma

Limin Zhen, Gang Ning, Lina Wu, Yongyuan Zheng, Fangji Yang, Tongtong Chen, Wenxiong Xu, Ying Liu, Chan Xie, Liang Peng
Journal: Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20192593.
DOI: https://doi.org/10.1042/BSR20192593
Published: 05 October 2020
...Limin Zhen; Gang Ning; Lina Wu; Yongyuan Zheng; Fangji Yang; Tongtong Chen; Wenxiong Xu; Ying Liu; Chan Xie; Liang Peng Objectives: To identify the prognostic value of aberrantly methylated differentially expressed genes (DEGs) in hepatocellular carcinoma (HCC) and to explore the underlying...
View article titled, Prognostic value of aberrantly expressed methylation genes in human <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Prognostic value of aberrantly expressed methylation genes in human <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Articles

Identification of hepatocellular carcinoma prognostic markers based on 10-immune gene signature

Kaifei Zhao, Lin Xu, Feng Li, Jin Ao, Guojun Jiang, Rongshu Shi, Fang Chen, Qing Luo
Journal: Bioscience Reports
Biosci Rep (2020) 40 (8): BSR20200894.
DOI: https://doi.org/10.1042/BSR20200894
Published: 28 August 2020
...Kaifei Zhao; Lin Xu; Feng Li; Jin Ao; Guojun Jiang; Rongshu Shi; Fang Chen; Qing Luo Background: Due to the heterogeneity of hepatocellular carcinoma (HCC), hepatocelluarin-associated differentially expressed genes were analyzed by bioinformatics methods to screen the molecular markers for HCC...
View article titled, Identification of <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> prognostic markers based on 10-immune gene signature
Click here to open pdf in another window PDF for Identification of <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> prognostic markers based on 10-immune gene signature
Includes: Supplementary data
Articles

Expression of concern: Effects of LncRNA-HOST2 on cell proliferation, migration, invasion and apoptosis of human hepatocellular carcinoma cell line SMMC-7721

Journal: Bioscience Reports
Biosci Rep (2020) 40 (8): BSR-20160532_EOC.
DOI: https://doi.org/10.1042/BSR-20160532_EOC
Published: 25 August 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Hepatocellular carcinoma Human ovarian cancer specific transcript 2 Long...
View article titled, Expression of concern: Effects of LncRNA-HOST2 on cell proliferation, migration, invasion and apoptosis of human <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cell line SMMC-7721
Click here to open pdf in another window PDF for Expression of concern: Effects of LncRNA-HOST2 on cell proliferation, migration, invasion and apoptosis of human <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cell line SMMC-7721
Articles

LncRNA HOTAIR contributes Taxol-resistance of hepatocellular carcinoma cells via activating AKT phosphorylation by down-regulating miR-34a

Yunfei Duan, Jing Chen, Yu Yang, Zhen Qu, Yunjie Lu, Donglin Sun
Journal: Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20201627.
DOI: https://doi.org/10.1042/BSR20201627
Published: 30 July 2020
...Yunfei Duan; Jing Chen; Yu Yang; Zhen Qu; Yunjie Lu; Donglin Sun Drug resistance of Taxol leads to the treatment failure in hepatocellular carcinoma (HCC). LncRNA HOTAIR have drawn increasing attention in various diseases; its function and mechanism in Taxol-resistance in HCC remain unclear...
View article titled, LncRNA HOTAIR contributes Taxol-resistance of <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cells via activating AKT phosphorylation by down-regulating miR-34a
Click here to open pdf in another window PDF for LncRNA HOTAIR contributes Taxol-resistance of <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cells via activating AKT phosphorylation by down-regulating miR-34a
Articles

Erianin suppresses hepatocellular carcinoma cells through down-regulation of PI3K/AKT, p38 and ERK MAPK signaling pathways

Liang Yang, Yue Hu, Guanbao Zhou, Qi Chen, Zhenshun Song
Journal: Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20193137.
DOI: https://doi.org/10.1042/BSR20193137
Published: 27 July 2020
...Liang Yang; Yue Hu; Guanbao Zhou; Qi Chen; Zhenshun Song Background: Hepatocellular carcinoma (HCC) is the dominant pathological type of primary liver cancer and no effective methods are available for its treatment. Erianin is a natural product extracted from Dendrobium , which possesses multiple...
View article titled, Erianin suppresses <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cells through down-regulation of PI3K&#x2F;AKT, p38 and ERK MAPK signaling pathways
Click here to open pdf in another window PDF for Erianin suppresses <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cells through down-regulation of PI3K/AKT, p38 and ERK MAPK signaling pathways
Articles

Revealing the clinical significance and prognostic value of small nucleolar RNA SNORD31 in hepatocellular carcinoma

Yuan Ding, Zhongquan Sun, Sitong Zhang, Qianhui Xu, Liuzhi Zhou, Dongkai Zhou, Yanjie Li, Xin Han, Hao Xu, Yang Bai, Chang Xu, Hao Ding, Yao Ge, Weilin Wang
Journal: Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20201479.
DOI: https://doi.org/10.1042/BSR20201479
Published: 22 July 2020
...Yuan Ding; Zhongquan Sun; Sitong Zhang; Qianhui Xu; Liuzhi Zhou; Dongkai Zhou; Yanjie Li; Xin Han; Hao Xu; Yang Bai; Chang Xu; Hao Ding; Yao Ge; Weilin Wang Background: For lack of accurate early diagnosis and prognostic assessment, hepatocellular carcinoma (HCC) becomes severe challenge...
View article titled, Revealing the clinical significance and prognostic value of small nucleolar RNA SNORD31 in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Revealing the clinical significance and prognostic value of small nucleolar RNA SNORD31 in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Articles

Identification of prognostic and metastasis-related alternative splicing signatures in hepatocellular carcinoma

Runzhi Huang, Gaili Yan, Hanlin Sun, Jie Zhang, Dianwen Song, Rui Kong, Penghui Yan, Peng Hu, Aiqing Xie, Siqiao Wang, Juanwei Zhuang, Huabin Yin, Tong Meng, Zongqiang Huang
Journal: Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20201001.
DOI: https://doi.org/10.1042/BSR20201001
Published: 15 July 2020
...Runzhi Huang; Gaili Yan; Hanlin Sun; Jie Zhang; Dianwen Song; Rui Kong; Penghui Yan; Peng Hu; Aiqing Xie; Siqiao Wang; Juanwei Zhuang; Huabin Yin; Tong Meng; Zongqiang Huang As the most common neoplasm in digestive system, hepatocellular carcinoma (HCC) is one of the most important leading cause...
View article titled, Identification of prognostic and metastasis-related alternative splicing signatures in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Identification of prognostic and metastasis-related alternative splicing signatures in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Includes: Supplementary data
Articles

Hsa_circ_0026134 expression promoted TRIM25- and IGF2BP3-mediated hepatocellular carcinoma cell proliferation and invasion via sponging miR-127-5p

Wei Zhang, Liang Zhu, Guowei Yang, Bo Zhou, Jianhua Wang, Xudong Qu, Zhiping Yan, Sheng Qian, Rong Liu
Journal: Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20191418.
DOI: https://doi.org/10.1042/BSR20191418
Published: 15 July 2020
... in hepatocellular carcinoma (HCC). We investigated hsa_circ_0026134 expression in 20 pairs of clinical tissues from HCC patients; expression of hsa_circ_0026134 in different cell lines; effect of hsa_circ_0026134 on proliferation and invasion of HCC cell lines; and the regulatory mechanisms and interactions among...
View article titled, Hsa_circ_0026134 expression promoted TRIM25- and IGF2BP3-mediated <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cell proliferation and invasion via sponging miR-127-5p
Click here to open pdf in another window PDF for Hsa_circ_0026134 expression promoted TRIM25- and IGF2BP3-mediated <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cell proliferation and invasion via sponging miR-127-5p
Articles

Exosomes function as nanoparticles to transfer miR-199a-3p to reverse chemoresistance to cisplatin in hepatocellular carcinoma

Kun Zhang, Chu-xiao Shao, Jin-de Zhu, Xin-liang Lv, Chao-yong Tu, Chuan Jiang, Min-jie Shang
Journal: Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20194026.
DOI: https://doi.org/10.1042/BSR20194026
Published: 06 July 2020
...Kun Zhang; Chu-xiao Shao; Jin-de Zhu; Xin-liang Lv; Chao-yong Tu; Chuan Jiang; Min-jie Shang Hepatocellular carcinoma (HCC) is a frequently seen malignant tumor globally. The occurrence of cisplatin (DDP) resistance is one of the main reasons for the high mortality of HCC patients. Therefore...
View article titled, Exosomes function as nanoparticles to transfer miR-199a-3p to reverse chemoresistance to cisplatin in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Click here to open pdf in another window PDF for Exosomes function as nanoparticles to transfer miR-199a-3p to reverse chemoresistance to cisplatin in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>
Articles

Development and validation of a nomogram for assessing survival in patients with hepatocellular carcinoma after hepatectomy

Rong-Rui Huo, Xu Liu, Jing Cui, Liang Ma, Kun-Hua Huang, Cai-Yi He, Yang Yang, Xue-Mei You, Wei-Ping Yuan, Bang-De Xiang, Jian-Hong Zhong, Le-Qun Li
Journal: Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20192690.
DOI: https://doi.org/10.1042/BSR20192690
Published: 16 June 2020
...Rong-Rui Huo; Xu Liu; Jing Cui; Liang Ma; Kun-Hua Huang; Cai-Yi He; Yang Yang; Xue-Mei You; Wei-Ping Yuan; Bang-De Xiang; Jian-Hong Zhong; Le-Qun Li Background and aim: Assessing the average survival rate of patients with hepatocellular carcinoma (HCC) after hepatectomy is important for making...
View article titled, Development and validation of a nomogram for assessing survival in patients with <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> after hepatectomy
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Articles

MicroRNA-4651 represses hepatocellular carcinoma cell growth and facilitates apoptosis via targeting FOXP4

Yun Li, Xiaoying Wang, Zhonggang Li, Bingxia Liu, Chaoyu Wu
Journal: Bioscience Reports
Biosci Rep (2020) 40 (6): BSR20194011.
DOI: https://doi.org/10.1042/BSR20194011
Published: 10 June 2020
...-4651 (miR-4651) was involved in hepatocellular carcinoma (HCC) progression. The certain role of miRNA-4651 during the progression of HCC, however, remains unclear. Herein, we investigated the mRNA expression level of miR-4651 in HCC tissues and HCC cell lines and found miR-4651 was noticeably down...
View article titled, MicroRNA-4651 represses <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cell growth and facilitates apoptosis via targeting FOXP4
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Articles

MiR-139-5p influences hepatocellular carcinoma cell invasion and proliferation capacities via decreasing SLITRK4 expression

Jisiguleng Wu, Tong Zhang, Yubo Chen, Sigaowa Ha
Journal: Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20193295.
DOI: https://doi.org/10.1042/BSR20193295
Published: 04 May 2020
...Jisiguleng Wu; Tong Zhang; Yubo Chen; Sigaowa Ha The microRNA, miR-139-5p, has been proved to play important roles in regulating tumor progression, including prostate cancer, osteosarcoma, esophageal cancer, and so on, but its correlation of hepatocellular carcinoma (HCC) still remains unclear...
View article titled, MiR-139-5p influences <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> cell invasion and proliferation capacities via decreasing SLITRK4 expression
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Articles

Immunohistochemical staining reveals differential expression of ACSL3 and ACSL4 in hepatocellular carcinoma and hepatic gastrointestinal metastases

Haarith Ndiaye, Jorlin Y. Liu, Andrew Hall, Shane Minogue, Marsha Y. Morgan, Mark G. Waugh
Journal: Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20200219.
DOI: https://doi.org/10.1042/BSR20200219
Published: 23 April 2020
... and subcellular localisations of the ACSL3 and ACSL4 isoforms in hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA) and hepatic metastases were assessed by immunohistochemical analyses of multiple tumour tissue arrays and by subcellular fractionation of cultured HepG2 cells. The expression of both enzymes...
View article titled, Immunohistochemical staining reveals differential expression of ACSL3 and ACSL4 in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> and hepatic gastrointestinal metastases
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Articles

Statin use and the prognosis of patients with hepatocellular carcinoma: a meta-analysis

Xiaofei Li, Liwen Liu, Yongtao Hu
Journal: Bioscience Reports
Biosci Rep (2020) 40 (4): BSR20200232.
DOI: https://doi.org/10.1042/BSR20200232
Published: 03 April 2020
...Xiaofei Li; Liwen Liu; Yongtao Hu Background: Association between statin use and prognosis in patients with hepatocellular carcinoma (HCC) remains unknown. We performed a meta-analysis of follow-up studies to systematically evaluate the influence of statin use on clinical outcome in HCC patients...
View article titled, Statin use and the prognosis of patients with <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>: a meta-analysis
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Articles

Retraction: MicroRNA-367 promotes progression of hepatocellular carcinoma through PTEN/PI3K/AKT signaling pathway

Journal: Bioscience Reports
Biosci Rep (2020) 40 (3): BSR-20182466_RET.
DOI: https://doi.org/10.1042/BSR-20182466_RET
Published: 13 March 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Hepatocellular carcinoma MiR-367 PTEN PI3K/AKT pathway Bioscience...
View article titled, Retraction: MicroRNA-367 promotes progression of <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> through PTEN&#x2F;PI3K&#x2F;AKT signaling pathway
Click here to open pdf in another window PDF for Retraction: MicroRNA-367 promotes progression of <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> through PTEN/PI3K/AKT signaling pathway
Articles

Long non-coding RNA RP11-284P20.2 promotes cell proliferation and invasion in hepatocellular carcinoma by recruiting EIF3b to induce c-met protein synthesis

Qin-Liang Fang, Jian-Yin Zhou, Yu Xiong, Cheng-Rong Xie, Fu-Qiang Wang, Yun-Tong Li, Zhen-Yu Yin, Guo-Hui Luo
Journal: Bioscience Reports
Biosci Rep (2020) 40 (3): BSR20200297.
DOI: https://doi.org/10.1042/BSR20200297
Published: 12 March 2020
...Qin-Liang Fang; Jian-Yin Zhou; Yu Xiong; Cheng-Rong Xie; Fu-Qiang Wang; Yun-Tong Li; Zhen-Yu Yin; Guo-Hui Luo A newly identified lncRNA designated as RP11-284P20.2 has been identified to be up-regulated in hepatocellular carcinoma (HCC), but its role in HCC remain poorly understood. Quantitative...
View article titled, Long non-coding RNA RP11-284P20.2 promotes cell proliferation and invasion in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> by recruiting EIF3b to induce c-met protein synthesis
Click here to open pdf in another window PDF for Long non-coding RNA RP11-284P20.2 promotes cell proliferation and invasion in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> by recruiting EIF3b to induce c-met protein synthesis
Articles

LINC00978 promotes hepatocellular carcinoma carcinogenesis partly via activating the MAPK/ERK pathway

Quan Zhang, Shujie Cheng, Liye Cao, Jihong Yang, Yu Wang, Yaqing Chen
Journal: Bioscience Reports
Biosci Rep (2020) 40 (3): BSR20192790.
DOI: https://doi.org/10.1042/BSR20192790
Published: 09 March 2020
...Quan Zhang; Shujie Cheng; Liye Cao; Jihong Yang; Yu Wang; Yaqing Chen Objective : To study the role of long non-coding RNA (lncRNA) LINC00978 in hepatocellular carcinoma (HCC) carcinogenesis. Materials and methods : LINC00978 expression level was measured by reverse transcription quantitative real...
View article titled, LINC00978 promotes <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> carcinogenesis partly via activating the MAPK&#x2F;ERK pathway
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Articles

Methylenetetrahydrofolate reductase C677T (Ala>Val, rs1801133 C>T) polymorphism decreases the susceptibility of hepatocellular carcinoma: a meta-analysis involving 12,628 subjects

Sheng Zhang, Jiakai Jiang, Weifeng Tang, Longgen Liu
Journal: Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20194229.
DOI: https://doi.org/10.1042/BSR20194229
Published: 20 February 2020
...) publications incompatible with HWE; (2) overlapping data; (3) not case–control study design and (4) only focusing on the relationship of MTHFR rs1801133 polymorphism with HCC survival. Hepatocellular carcinoma Meta-analysis MTHFR Polymorphism Susceptibility In 2018, global cancer...
View article titled, Methylenetetrahydrofolate reductase C677T (Ala&amp;gt;Val, rs1801133 C&amp;gt;T) polymorphism decreases the susceptibility of <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>: a meta-analysis involving 12,628 subjects
Click here to open pdf in another window PDF for Methylenetetrahydrofolate reductase C677T (Ala&gt;Val, rs1801133 C&gt;T) polymorphism decreases the susceptibility of <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span>: a meta-analysis involving 12,628 subjects
Articles

Clusterin role in hepatocellular carcinoma patients treated with oxaliplatin

Xiumei Wang, Yongqiang Liu, Qiong Qin, Ti Zheng
Journal: Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20200071.
DOI: https://doi.org/10.1042/BSR20200071
Published: 20 February 2020
...Xiumei Wang; Yongqiang Liu; Qiong Qin; Ti Zheng Aim: To explore the prognostic value of clusterin ( CLU ) in hepatocellular carcinoma (HCC) patients treated with oxaliplatin (OXA). Methods: Relative expression of plasma CLU mRNA was examined via fluorescence quantitative real-time PCR (qRT-PCR...
View article titled, Clusterin role in <span class="search-highlight">hepatocellular</span> <span class="search-highlight">carcinoma</span> patients treated with oxaliplatin
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