... and plant-dominated fiber-rich food in lowering the risk of coronary heart diseases [ 17 ]. However, a case–cohort study in Finnish male smokers identified a weak association between serum enterolactone concentration and the risk of development of coronary heart disease [ 33 ]. It is possible that smoking...

... in endothelial PAS domain-containing protein 1 (EPAS1) in congenital heart disease in Tibetans. In humans, the EPAS1 gene is responsible for coding EPAS1 protein, an alias of which is HIF2α, an acronym for hypoxia-inducible factor 2 alpha. EPAS1 is a type of hypoxia-inducible factors, which are collected...

.... However, its effect on energetics in heart remains unknown. In the present study, we examined respiration in cardiac muscle and liver from adult mice that were undernourished in utero . We report that in utero undernutrition is associated with impaired cardiac muscle energetics, including decreased fatty...

...-activated protein kinase glucose heart insulin pentose phosphate pathway AMPK (AMP-activated protein kinase) is a heterotromeric (αβγ) serine/threonine protein kinase that is a regulator of energy homoeostasis at the cellular and the whole-body level [ 1 , 2 ]. AMPK is activated during energy...

... fraction. The presence of these enzymes in the heart probably has a physiological function in adenosine signalling. Furthermore, the presence of ecto-5′-nucleotidase in the microsomal fraction could have a role in the modulation of the excitation–contraction-coupling process through involvement of the Ca 2...

... rat heart atria and ventricles. Rat IRCM-SP1 was shown to be highly specific for the same cleavage sites in POMC, as the porcine pituitary homologue. Furthermore, the rat and the porcine enzymes cleave rat pro-Atrial Natriuretic Factor (pro-ANF 1–126) to yield ANF 103–126, 102–126 and 99–126...