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Keywords: heart
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Biosci Rep (2020) 40 (5): BSR20200454.
Published: 15 May 2020
... BY) . coronary artery disease gut microbiota heart ischemia trimethylamine-N-oxide Gut microbiota refers to a complex community of all types of microorganisms residing in the gastrointestinal tract in humans and other organisms in a mutualistic relationship. Although the majority of microorganisms...
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Biosci Rep (2019) 39 (5): BSR20182197.
Published: 10 May 2019
... in endothelial PAS domain-containing protein 1 (EPAS1) in congenital heart disease in Tibetans. In humans, the EPAS1 gene is responsible for coding EPAS1 protein, an alias of which is HIF2α, an acronym for hypoxia-inducible factor 2 alpha. EPAS1 is a type of hypoxia-inducible factors, which are collected...
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Biosci Rep (2015) 35 (3): e00200.
Published: 11 June 2015
.... However, its effect on energetics in heart remains unknown. In the present study, we examined respiration in cardiac muscle and liver from adult mice that were undernourished in utero . We report that in utero undernutrition is associated with impaired cardiac muscle energetics, including decreased fatty...
Includes: Supplementary data
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Biosci Rep (2012) 32 (3): 229–239.
Published: 22 December 2011
... increase AMPK activity/phosphorylation in perfused rat heart [ 8 ] and in skeletal muscle cells [ 9 ]. The activity of ACC-2 (acetyl-coA carboxylase-2), the muscle isoform of ACC, is decreased following phosphorylation by AMPK. Malonyl-CoA, the product of the ACC reaction, allosterically inhibits CPT-1...
Includes: Supplementary data
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