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Keywords: glycolysis
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Biosci Rep (2021) 41 (11): BSR20211847.
Published: 18 November 2021
... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . dexamethasone Glycolysis Kidney PPAR RNA-Seq GO is a gene function classification system that provides a set...
Includes: Supplementary data
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Biosci Rep (2021) 41 (8): BSR20211451.
Published: 27 August 2021
...Wei Ma; Manli Zhong; Xiaowu Liu Background: The present study investigated the independent prognostic value of glycolysis-related long noncoding (lnc)RNAs in clear cell renal cell carcinoma (ccRCC). Methods: A coexpression analysis of glycolysis-related mRNAs–long noncoding RNAs (lncRNAs) in ccRCC...
Includes: Supplementary data
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Biosci Rep (2021) 41 (2): BSR20203982.
Published: 19 February 2021
...Kai Che; Wenkai Han; Danxia Li; Shuxia Cui; Mingxin Zhang; Xiaokun Yang; Haitao Niu Background: Glycolysis was a representative hallmark in the tumor microenvironment (TME), and we aimed to explore the correlations between glycolysis with immune activity and clinical traits in bladder urothelial...
Includes: Supplementary data
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Biosci Rep (2020) 40 (4): BSR20193512.
Published: 24 April 2020
... ) and catabolism (P 4 ) and increase pyruvate and lactate levels in culture. We measured the rate of glucose uptake and glycolysis in a mink immortalized epithelial cell line (GMMe) after 24-h exposure to 10 μM P 4 and 10 nM E 2 (pharmacologic levels) at 5 mM glucose and determined the kinetic parameters ( V max...
Includes: Supplementary data
Articles
Biosci Rep (2019) 39 (7): BSR20182270.
Published: 30 July 2019
... and BIU87 cells with ectopic LHPP expression. LHPP also repressed the glycolysis of BC cells. At the molecular level, LHPP silencing led to enhanced phosphorylation of both AKT and p65, as well as up-regulation of their downstream targets Bcl-2 and Cyclin D1. Inhibition of AKT by MK2206 blunted...
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Biosci Rep (2019) 39 (7): BSR20182442.
Published: 02 July 2019
... via inhibiting the glycolysis of HCC cells. These findings suggested miR-505 as an interesting target for designing anti-cancer strategy in HCC. Correspondence: Shengqiang Wang ( linchuang_05@sina.com ) 01 01 2019 14 05 2019 31 05 2019 03 06 2019 © 2019 The Author(s...
Includes: Supplementary data
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Articles
Biosci Rep (2018) 38 (4): BSR20180580.
Published: 03 July 2018
... patients. CXCL1 expression levels and their associations with clinicopathological characteristics and patient survival were evaluated. The effect of CXCL1 on glycolysis was also examined . High CXCL1 expression was detected in 165 (59.8%) cases. CXCL1 expression was correlated with tumor diameter ( P...
Articles
Biosci Rep (2017) 37 (6): BSR20170925.
Published: 06 November 2017
.... Interestingly, an adaptive up-regulation of miR-34a by long-time hypoxia was observed both in vitro and in vivo , leading to suppression of glycolysis in cardiomyocytes. We identified lactate dehydrogenase-A (LDHA) as a direct target of miR-34a , which binds to the 3′-UTR region of LDHA mRNA in cardiomyocytes...
Articles
Biosci Rep (2015) 35 (3): e00205.
Published: 12 June 2015
...Nadezda Bryan; Kevin P. Raisch Hexokinase II (HKII) is responsible for the first step in the glycolysis pathway by adding a phosphate on to the glucose molecule so it can proceed down the pathway to produce the energy for continuous cancer cell growth. Tumour cells overexpress the HKII enzyme...
Articles
Biosci Rep (2013) 33 (6): e00080.
Published: 15 November 2013
... regulation that shifts the balance between the cell cycle and apoptosis and those that involve the plasticity of the metabolic machinery. With regards to metabolism, the selected phenotypes usually display enhanced anaerobic glycolysis even in the presence of oxygen, the so-called Warburg effect...
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Articles
Biosci Rep (1997) 17 (6): 521–527.
Published: 01 December 1997
...Elena V. Schmalhausen; Vladimir I. Muronetz Data on alterations of the properties of glyceraldehyde-3-phosphate dehydrogenase upon oxidation of its functional groups are reviewed; a mechanism of uncoupling of oxidation and phosphorylation in glycolysis is considered. Possible ways of regulating...