... and the differentiation of T lymphocytes. © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . dexamethasone Glycolysis Kidney PPAR RNA-Seq...

... using cell counting kit-8 (CCK-8) assay. Glycolysis and mitochondrial function were evaluated by measuring the extracellular acidification rate (ECAR) and the oxygen consumption rate (OCR) of cells, respectively. Lastly, plasmid transfection and inhibitor treatment were used for overexpression...

...Wei Ma; Manli Zhong; Xiaowu Liu Background: The present study investigated the independent prognostic value of glycolysis-related long noncoding (lnc)RNAs in clear cell renal cell carcinoma (ccRCC). Methods: A coexpression analysis of glycolysis-related mRNAs–long noncoding RNAs (lncRNAs) in ccRCC...

.... Functional enrichment analysis indicated that the potential targets might be significantly involved in glycolysis and the HIF-1 signaling pathway. To further confirm the effect of BSJPF on ccRCC cell proliferation, a BALB/c xenograft mouse model was constructed. Potential targets involved in regulating...

...Kai Che; Wenkai Han; Danxia Li; Shuxia Cui; Mingxin Zhang; Xiaokun Yang; Haitao Niu Background: Glycolysis was a representative hallmark in the tumor microenvironment (TME), and we aimed to explore the correlations between glycolysis with immune activity and clinical traits in bladder urothelial...

...Sihan Chen; Guodong Cao; Wei Wu; Yida Lu; Xiaobo He; Lei Yang; Ke Chen; Bo Chen; MaoMing Xiong Colon adenocarcinoma (COAD) is a malignant gastrointestinal tumor, often occurring in the left colon, which is regulated by glycolysis-related processes. In past studies, multiple genes that influence...

.../mTOR breast cancer cells glycolysis cisplatin drug resistance WITHDRAWN ARTICLE WITHDRAWN: SIK2 Promotes Cisplatin Resistance Induced by Aerobic Glycolysis in Breast Cancer Cells through PI3K/AKT/mTOR Signaling Pathway Shoukai Zong, Wei Dai, Wencheng Fang, Xiangting Guo, Kai Wang Bioscience...

... ) and catabolism (P 4 ) and increase pyruvate and lactate levels in culture. We measured the rate of glucose uptake and glycolysis in a mink immortalized epithelial cell line (GMMe) after 24-h exposure to 10 μM P 4 and 10 nM E 2 (pharmacologic levels) at 5 mM glucose and determined the kinetic parameters ( V max...

... and BIU87 cells with ectopic LHPP expression. LHPP also repressed the glycolysis of BC cells. At the molecular level, LHPP silencing led to enhanced phosphorylation of both AKT and p65, as well as up-regulation of their downstream targets Bcl-2 and Cyclin D1. Inhibition of AKT by MK2206 blunted...

... via inhibiting the glycolysis of HCC cells. These findings suggested miR-505 as an interesting target for designing anti-cancer strategy in HCC. Correspondence: Shengqiang Wang ( linchuang_05@sina.com ) 01 01 2019 14 05 2019 31 05 2019 03 06 2019 © 2019 The Author(s...

... of mitochondrial oxidative phosphorylation (OxPhos). As a function of its exposure time, Minerval compromised the capacity of glioblastoma U87-MG cells to compensate for aberrant respiration by up-modulation of glycolysis. This effect was not exposure time-dependent in the lung carcinoma A549 cell line, which...

... patients. CXCL1 expression levels and their associations with clinicopathological characteristics and patient survival were evaluated. The effect of CXCL1 on glycolysis was also examined . High CXCL1 expression was detected in 165 (59.8%) cases. CXCL1 expression was correlated with tumor diameter ( P...

.... Interestingly, an adaptive up-regulation of miR-34a by long-time hypoxia was observed both in vitro and in vivo , leading to suppression of glycolysis in cardiomyocytes. We identified lactate dehydrogenase-A (LDHA) as a direct target of miR-34a , which binds to the 3′-UTR region of LDHA mRNA in cardiomyocytes...

...Nadezda Bryan; Kevin P. Raisch Hexokinase II (HKII) is responsible for the first step in the glycolysis pathway by adding a phosphate on to the glucose molecule so it can proceed down the pathway to produce the energy for continuous cancer cell growth. Tumour cells overexpress the HKII enzyme...

... regulation that shifts the balance between the cell cycle and apoptosis and those that involve the plasticity of the metabolic machinery. With regards to metabolism, the selected phenotypes usually display enhanced anaerobic glycolysis even in the presence of oxygen, the so-called Warburg effect...

... the cold acclimation process. 1 To whom correspondence should be addressed (email wseixas@bioqmed.ufrj.br ). 16 10 2009 4 1 2010 7 1 2010 7 1 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 glycolysis goldfish hexokinase (HK) mitochondria...

...Elena V. Schmalhausen; Vladimir I. Muronetz Data on alterations of the properties of glyceraldehyde-3-phosphate dehydrogenase upon oxidation of its functional groups are reviewed; a mechanism of uncoupling of oxidation and phosphorylation in glycolysis is considered. Possible ways of regulating...