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Keywords: drug discovery
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Biosci Rep (2014) 34 (4): e00133.
Published: 11 August 2014
... to identify novel inhibitors of hDAAO (human D -amino acid oxidase), an enzyme relevant for schizophrenia and neuropathic pain. These inhibitors stabilized a hDAAO conformation with the enzyme's active-site lid open. crystallography DAAO DAO drug discovery NMDA receptor schizophrenia DAAO...
Includes: Supplementary data