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Keywords: differentiation
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Biosci Rep (2021) 41 (4): BSR-20130120_EOC.
Published: 09 April 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . adipogenesis chicken differentiation fatty acid inducer preadipocyte...
Biosci Rep (2021) 41 (2): BSR20203998.
Published: 12 February 2021
..., proliferation, migration and cell differentiation culminates in cell elongation and organelle degradation, allowing the light to reach the retina. HOPS ( H epatocyte O dd P rotein S huttling)/TMUB1 ( T rans M embrane Ub iquitin-like containing protein 1 ) is a nucleo-cytoplasmic shuttling protein, highly...
Biosci Rep (2021) 41 (1): BSR20202298.
Published: 22 January 2021
... dissection differentiation LncRNA H19 miR-193b-3p smooth muscle cell Aortic rupture/dissection (AD) is caused by an intima-media tear in the aorta under the impact of high velocity and pressure blood flow, forming a false or true lumen [ 1 ]. AD has a high mortality rate and a poor prognosis...
Includes: Supplementary data
Biosci Rep (2020) 40 (10): BSR20193531.
Published: 23 October 2020
... of migration, proliferation and differentiation. MicroRNAs (miRNAs) are small non-coding RNAs that play important roles on regulating various cell behaviors. Here, we report that miRNA-124 (miR124) and miRNA-21-5p (miR21-5p) display different regulatory roles on migration, proliferation and neuron...
Biosci Rep (2020) 40 (9): BSR20201227.
Published: 02 September 2020
...-β1 treatment dose-dependently curbed miR-29b-3p expression in CFs. miR-29b-3p restrained the promotive impacts of TGF-β1 on CFs proliferation, migration, and differentiation. FOS was affirmed to be a target of miR-29b-3p, elevated expression of FOS reversed the inhibitory effects of miR-29b-3p...
Biosci Rep (2019) 39 (10): BSR20182048.
Published: 11 October 2019
...Suxuan Liu; Wen Ke; Yang Liu; Zhenzhen Zhao; Lina An; Xiaohua You; Fan Yang; Xiangqun Yang; Guokun Wang; Xianxian Zhao Background: Cardiac fibroblasts differentiation plays a critical role in cardiac remodeling and failure, but the underlying molecular mechanisms are still poorly understood...
Includes: Supplementary data
Biosci Rep (2018) 38 (5): BSR20180707.
Published: 14 September 2018
... the trans-regulatory effects of transcription factors, we found that Cped1 expression was significantly reduced ( Figure 4 I). Above results indicated that histone acetylation could co-operate with Sox2 in regulating Cped1 expression. chicken differentiation Histone acetylation Spermatogonial...
Includes: Supplementary data
Biosci Rep (2018) 38 (2): BSR20171497.
Published: 27 April 2018
...Anita Ferraretto; Michela Bottani; Paola De Luca; Laura Cornaghi; Francesca Arnaboldi; Margherita Maggioni; Amelia Fiorilli; Elena Donetti An intestinal 70/30 Caco2/HT-29 co-culture was set up starting from the parental populations of differentiated cells to mimic the human intestinal epithelium...
Biosci Rep (2017) 37 (3): BSR20160566.
Published: 27 June 2017
... extracts. The microspheres had a smooth surface and were spherical in shape. The average diameter of the microspheres was 3.95 µm. The loading efficiency was approximately 2.12%. The purity of isolated hBMSC was over 98.8%. Rg1-loaded microspheres could promote hBMSC proliferation and differentiation...
Biosci Rep (2017) 37 (2): BSR20170637.
Published: 20 April 2017
...). However, it remains unknown whether mouse embryonic stem cells (ESCs) can directly differentiate into advanced male germ cell lineage in the same conditions. Here, we showed rather low efficiency of germ-like cell generation from mouse ESCs in SSC conditions. Interestingly, addition of retinoic acid (RA...
Biosci Rep (2016) 36 (6): e00401.
Published: 03 November 2016
...Bohan Cheng; Mengqi Wu; Songsong Xu; Xinyang Zhang; Yuxiang Wang; Ning Wang; Li Leng; Hui Li The preadipocyte differentiation biological process involves a cascade of transcriptional events that culminates in the expression of peroxisome proliferator-activated receptor (PPAR) γ. The differentiation...
Biosci Rep (2015) 35 (6): e00269.
Published: 26 November 2015
... cysteines. Previously, we reported that the classical form of cytosolic TrxR1 (TXNRD1_v1), when overexpressed in human embryonic kidney cells (HEK-293), prompted the cells to undergo differentiation [Nalvarte et al. (2004) J. Biol. Chem. 279 , 54510–54517]. In the present study, we show that several genes...
Includes: Supplementary data
Biosci Rep (2015) 35 (5): e00245.
Published: 10 September 2015
... study, miR-146 overexpression and predicted target (notch 1) were used to study proliferation and differentiation of mouse NSCs. shRNA were used to demonstrate the function of Notch 1 in proliferation of mouse NSCs and luciferase reporter assay was used to assess and confirm the binding sequence of 3...
Biosci Rep (2014) 34 (4): e00125.
Published: 29 July 2014
... neuroblast divides asymmetrically to produce a larger daughter cell that retains neuroblast identity, and a smaller daughter cell that is committed to undergo differentiation. Neuroblast self-renewal and differentiation are tightly controlled by a set of intrinsic factors that regulate ACD (asymmetric cell...
Biosci Rep (2014) 34 (1): e00093.
Published: 07 February 2014
...Zhouchun Shang; Lin Guo; Ning Wang; Hui Shi; Yuxiang Wang; Hui Li In addition to providing energy and constituting cell membrane, fatty acids also play an important role in adipocyte differentiation and lipid metabolism. As an important member of monounsaturated fatty acids, oleate, together...
Biosci Rep (2013) 33 (2): e00032.
Published: 28 March 2013
... observed the gene expression of pluripotent markers in foetal pMSCs and the capacity of pMSCs to differentiate into adipocytes, osteocytes and neural-like cells using quantitative RT–PCR (reverse transcription–PCR), normal histological staining and immunohistochemistry. Foetal pMSCs have either a spindle...
Biosci Rep (2011) 31 (4): 231–244.
Published: 02 March 2011
... is spatially and temporally regulated to act on Ras family GTPases Rap1, Rap2, R-Ras, TC21 and Rho family member TC10. Increased C3G protein levels are associated with differentiation of various cell types, indicating an important role for C3G in cellular differentiation. In signalling pathways, C3G serves...
Biosci Rep (2011) 31 (2): 77–86.
Published: 29 October 2010
... and differentiation. Moreover, perturbation of those chromatin regulators results in loss of ES cell identity or aberrant differentiation. Therefore, it is important to fully understand the chromatin regulation landscape of ES cells. The knowledge gained will help us to harness the unique characteristics of ES cells...
Biosci Rep (2010) 30 (3): 149–158.
Published: 15 December 2009
...-differentiation of stem cells on the PNIPAAm-grafted PDMS surface. The results showed that hMSCs could adhere on the PNIPAAm-grafted PDMS surface at 37°C and form cell colonies, and then become fibroblastic. The proliferation potential of hMSCs on the PNIPAAm-grafted PDMS surface was not significantly different...
Biosci Rep (2007) 27 (1-3): 165–171.
Published: 13 June 2007
... disorders are also reported. © 2007 The Biochemical Society 2007 Mitochondria Stem cells Differentiation Mitochondrial localization ROS MNGIE MINI REVIEW The Role of Mitochondria in Stem Cell Biology Claudia Nesti Æ Livia Pasquali Æ Francesca Vaglini Æ Gabriele Siciliano Æ Luigi Murri...
Biosci Rep (1994) 14 (6): 259–281.
Published: 01 December 1994
... of the liquid matrix of cell membranes appears to be responsible for its effects and this appears also to be true for related effects on membrane permeability and fusion. Dimethyl sulphoxide is also known to act as an inducer of cellular differentiation and as a free radical scavenger and radioprotectant...
Biosci Rep (1990) 10 (3): 293–299.
Published: 01 June 1990
...Ewa Rydell; Karl-Eric Magnusson; Anita Sjö; Krister Axelsson Protein kinase C (PK-C) and casein kinase II (CK-II) activities were studied in two human colon carcinoma cell lines (HT-29 and CaCO-2) undergoing differentiation in vitro resulting, in small-intestine-like cells. CaCo-2 cells, when grown...
Biosci Rep (1990) 10 (2): 141–154.
Published: 01 April 1990
...Elvira Cuenllas; Soledad Gaitan; Juan A. Bueren; Concepcion Tejero Pyruvate kinase studies in the granulocyte-macrophage lineage during in vitro differentiation have been performed using culture techniques on GM-CFC cells and a study has also been done in bone marrow cells. The enzyme exhibits...
Biosci Rep (1986) 6 (1): 95–101.
Published: 01 January 1986
...Takashi Momoi; Haruki Senoo; Hiroshi Yoshikura The differentiation of HL-60 cells induced by 1α,25 dihydroxyvitamin D 3 was found to be separated into two stages, i.e. commitment and promotion. Most of the HL-60 cells were committed to monocyte/macrophage lineage by pretreatment with 1α,25...