...Xiaoming Li; Feixiang Lin; Yaohong Wu; Ning Liu; Jun Wang; Rongchun Chen; Zhijun Lu Intervertebral disc degeneration is a disease identified as an inflammation response-participated pathological process. As a classical cellular feature, disc cell senescence is reported to be closely related...

... 10.1002/jcb.27126 23. Xie J. , Li B. , Zhang P. , Wang L. , Lu H. and Song X. ( 2018 ) Osteogenic protein-1 attenuates the inflammatory cytokine-induced NP cell senescence through regulating the ROS/NF-kappaB pathway . Biomed. Pharmacother. 99 , 431 – 437...

... nucleus pulposus (NP) cell senescence in vitro and the potential mechanism. The isolated rat NP cells were seeded in the decalcified bone matrix (DBM) and cultured under non-compression (control) and compression (20% deformation, 1.0 Hz, 6 h/day) for 5 days using the mechanically active bioreactor...

...Jing Wang; Yuzhi Bai; Xia Zhao; Jing Ru; Ning Kang; Tian Tian; Liying Tang; Yun An; Pei Li Atherosclerosis develops as a consequence of inflammation and cell senescence. In critical factors involved in the atherosclerotic changes, reactive oxygen species (ROS) generation is considered a leading...

... gene (where C t is the cycle number when the fluorescence signal reaches the set threshold). The amplification parameters were: 95°C for 30 s (95°C for 5 s, 60°C for 34 s) for 40 cycles. cell senescence cellular memory hematopoietic stem/progenitor cells β-galactosidase Senescence...