.... The purpose of the present study was to determine the association between four candidate single nucleotide polymorphisms (SNPs) in STAT4 genes and HCC risk in Chinese Han population. Methods: A case–control study was conducted to assess the association between STAT4 SNPs and HCC risk in 1011 Chinese Han...

..., Begg’s rank correlation, and Egger’s linear regression were used to determine the possibility of publication bias. Results: The study was reviewed according to the project guidelines for optimal reporting (PRISMA) based on meta-analysis. A total of 30 case–control studies were included, with a total...

...) of ZBTB20 and the risk of gastric cancer in Chinese Han population. Methods: We conducted a ‘case–control’ study involving 509 GC patients and 507 healthy individuals. We selected four SNPs of ZBTB20 (10934270 T/C, rs9288999 G/A, rs9841504 G/C and rs73230612 C/T), and used logistic regression to analyze...

... 2020 04 08 2020 © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . case-control study liver cancer MIR17HG single...

... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Case–control study GREM2 osteoporosis postmenopausal women Osteoporosis is a systemic condition wherein patients exhibit low bone mass and microstructural degeneration of osseous tissue...

... Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . IL-17 case-control study colorectal cancer SNPs Colorectal cancer (CRC) is the third most common cancer and the fourth most common cause of cancer death [ 1 ]. More than 1.2 million patients...

... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . case-control study myocardial infarction polymorphism TGF-β1 Myocardial infarction (MI), a clinical complication...

... BY) . case-control study colorectal cancer EGF Single nucleotide polymorphism Colorectal cancer (CRC) is the second leading cause of cancer deaths in Europe and the United States [ 1 ]. Previous data showed that 140,250 new cases of CRC were diagnosed in women and men, and 50,630 women and men...

... in different populations has been extensively studied. However, the findings are conflicting, and there is no relevant research in Chinese subjects. Therefore, this case–control study involving 327 cases (type 2 diabetes patients with proliferative DR (PDR)) and 461 controls (type 2 diabetes patients without...

...-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and knee OA. However, the results were conflicting. To determine the association between ACE gene I/D polymorphism and knee OA, we conducted a hospital-based case–control study with 282 knee OA cases and 316 controls to investigate...

... the susceptibility of multiple cancers. However, the relationship of HIFs polymorphisms (rs11549467 and rs17039192) and breast cancer (BC) risk was still unknown. Thus, we performed a case-control study based on 560 BC patients and 583 healthy controls to explore the association between them. Our results indicated...

... infarction (MI). However, the results are inconsistent. In order to explore the relationship between the rs3850641 polymorphism of the TNFSF4 gene and MI, we conducted a case–control study including 454 cases and 512 controls in a Chinese Han population. Genotyping was performed using matrix-assisted laser...

... the Creative Commons Attribution License 4.0 (CC BY) . case-control study genetic susceptibility nucleotide excision repair ovarian cancer polymorphism Ovarian cancer is the most deadly gynecological malignancy that mainly affects women in the period of childbearing age, perimenopause...