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Keywords: blood brain barrier
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Articles

Peripheral inflammation promotes brain tau transmission via disrupting blood–brain barrier

Yanchao Liu, Shujuan Zhang, Xiaoguang Li, Enjie Liu, Xin Wang, Qiuzhi Zhou, Jinwang Ye, Jian-Zhi Wang
Journal: Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20193629.
DOI: https://doi.org/10.1042/BSR20193629
Published: 20 February 2020
... blocking microglia activation. Further studies demonstrated that LPS disrupted the integrity of blood–brain barrier (BBB) and simultaneous intraperitoneal administration of glucocorticoid (GC) attenuated LPS-promoted P301L-hTau transmission. These data together suggest that a non-microglia-dependent BBB...
View article titled, Peripheral inflammation promotes brain tau transmission via disrupting <span class="search-highlight">blood</span>–<span class="search-highlight">brain</span> <span class="search-highlight">barrier</span>
Click here to open pdf in another window PDF for Peripheral inflammation promotes brain tau transmission via disrupting <span class="search-highlight">blood</span>–<span class="search-highlight">brain</span> <span class="search-highlight">barrier</span>
Includes: Supplementary data