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Keywords: bioinformatics analysis
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Biosci Rep (2022) 42 (7): BSR20221168.
Published: 22 July 2022
... Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics analysis gene mutations poor prognosis thyroid cancer TTN gene Thyroid cancer (THCA) is the most common endocrine malignancy, and its incidence...
Includes: Supplementary data
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Biosci Rep (2022) 42 (2): BSR20212035.
Published: 04 February 2022
...Yao Song; Meiling Lu; Lijin Feng; Qian Chen; Hua Huang; Qing Lin Breast cancer is a serious malignancy with a high incidence worldwide and a tendency to relapse. We used integrated bioinformatics analysis to identify potential biomarkers in breast carcinoma in the present study. Microarray data...
Includes: Supplementary data
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Biosci Rep (2021) 41 (12): BSR20211420.
Published: 08 December 2021
... of the present study was to apply bioinformatics analysis to explore tumor-educated platelet (TEP) microRNA (miRNA) expression and its potential diagnostic utility in HCC. Methods: Twenty-five HCC patients and 25 healthy controls were included. RNA sequencing was utilized to screen miRNA alterations in platelets...
Includes: Supplementary data
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Biosci Rep (2021) 41 (2): BSR20194464.
Published: 10 February 2021
... established by STRING and Cytoscape software for further study. Finally, miRNAs targeted HSP90AA1 were predicted by miRanda. All in all, based on the data of GSE20479 chip, the molecular mechanism of SFN on hepatocytes was studied by a series of bioinformatics analysis methods, and it indicated that SFN might...
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Biosci Rep (2021) 41 (1): BSR20203699.
Published: 19 January 2021
...://software.broadinstitute.org/morpheus ). bioinformatics analysis gene expression profile microarray Skeletal muscle healing wound age Skeletal muscle tissues, which are widely distributed throughout the body, account for 30–50% of total body mass [ 1 , 2 ]. These tissues have a relatively superficial location...
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Biosci Rep (2021) 41 (1): BSR20193517.
Published: 06 January 2021
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics analysis Differentially expressed gene Microarray Pediatric atopic dermatitis Atopic dermatitis (AD) is the most common inflammatory skin disease with an estimated prevalence...
Includes: Supplementary data
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Biosci Rep (2020) 40 (6): BSR20194324.
Published: 25 June 2020
... BY) . bioinformatics analysis prognosis serous ovarian cancer TIMER database analysis tumor metastasis weighted gene coexpression network analysis (WGCNA) As one of the most prevalent malignancies in gynecology, ovarian cancer carries the highest mortality [ 1 ]. Most patients are diagnosed at an advanced...
Includes: Supplementary data
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Biosci Rep (2020) 40 (5): BSR20191227.
Published: 05 May 2020
... article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics analysis Breast cancer CDC20 Prognosis Total RNA was isolated using TRIzol reagent (TaKaRa, Japan) and 1000 ng...
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Biosci Rep (2020) 40 (2): BSR20193101.
Published: 24 February 2020
..., including eotaxin-2, eotaxin-3, CCL18, IL-4, IL-5, IL-10, IL-12p70, IL-13, and IL-15. Bioinformatics analysis indicated that these mediators were mainly enriched in leukocyte chemotaxis and proliferation, JAK-STAT cascade, asthma, and Th1 and Th2 cell differentiation. Furthermore, seven mediators were...
Includes: Supplementary data
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Biosci Rep (2020) 40 (2): BSR20193286.
Published: 18 February 2020
...) and disease-free survival (DFS). COL10A1 was positively correlated with metastatic relapse-free survival. GSEA analysis revealed that enrichment of TGF-β signaling pathway. 15-leucine-rich repeat containing membrane protein ( LRRC15 ) is a correlated gene of COL10A1. Conclusion: Bioinformatics analysis...
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Biosci Rep (2019) 39 (7): BSR20190855.
Published: 26 July 2019
... for subsequent genes functional researches, which could contribute to provide new therapeutic targets for AS. Correspondence: Liqun Ren ( renliqun0210@126.com ) atherosclerosis bioinformatics analysis icariin long non-coding RNA microarray Atherosclerosis (AS), characterized by progressing...
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Biosci Rep (2019) 39 (7): BSR20190996.
Published: 05 July 2019
... mRNA. Triangles indicate circRNAs, diamonds indicate miRNA, and ellipses indicate mRNA. The nodes highlighted in red and blue represent up-regulation and down-regulation, respectively. Figure 1 Heat map of the 8 differentially expressed circRNAs of the GSE100186 dataset bioinformatics...
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Biosci Rep (2019) 39 (5): BSR20181016.
Published: 02 May 2019
... migration of cervical cancer cells. Bioinformatics analysis showed that adherens junction was significant for both P -value and enrichment scores, which was consistent with the clinical study. The underlying molecular mechanisms might be the interaction among HMGB1, RAC1, and CDC42. HMGB1 expression...
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Biosci Rep (2019) 39 (1): BSR20181293.
Published: 03 January 2019
... BY) . bioinformatics analysis Diffuse large B cell lymphoma differentially expressed genes protein-protein interaction network survival analysis Diffuse large B-cell lymphoma (DLBCL), the most frequently diagnosed subtype of hematological cancers, is a molecular heterogeneous disease with an annual...
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Biosci Rep (2017) 37 (6): BSR20170884.
Published: 12 December 2017
... to indicate a significant difference. © 2017 The Author(s). 2017 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . breast cancer bioinformatics analysis CD28...
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Biosci Rep (2015) 35 (6): e00273.
Published: 26 November 2015
... non-coding (Lnc)RNAs regulated by Hec1 were gained from bioinformatics analysis. The role of LncRNA BX647187, regulated by Hec1, was finally characterized in PCa cells by siRNA. Our results showed that Hec1 mRNA and protein were significantly overexpressed in Human PCa tissues and several PCa cell...