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Keywords: bioinformatics
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Articles
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (5): BSR20230067.
Published: 18 May 2023
... . In addition, quantitative proteomics and bioinformatics analysis confirmed that PPT1 acts by affecting the metabolism, localization, and function of various macromolecular proteins. The present study reveals that PPT1 could be a promising therapeutic target for the treatment of HCC. These findings provided...
Includes: Supplementary data
Articles
Rodolfo Gamaliel Avila-Bonilla, Jorge Antonio Velazquez-Guzman, Eimy Itzel Reyes-Zepeda, Jorge Luis Gutierrez-Avila, César A Reyes-López, Alondra Cisneros-Sarabia, Emma Saavedra, Angel Lopéz-Sandoval, Esther Ramírez-Moreno, César López-Camarillo, Laurence A. Marchat
Journal:
Bioscience Reports
Biosci Rep (2023) 43 (2): BSR20221911.
Published: 09 February 2023
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Correspondence: Laurence A. Marchat ( lmarchat@ipn.mx ) bioinformatics mRNA processing protein-protein interactions protozoa therapeutic markers Gene expression regulation allows...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (8): BSR20212835.
Published: 31 August 2022
... investigated by bioinformatic analyses. Results: A ferroptosis-related gene signature ( ALOX5, TFRC, PHKG2, FADS2, NOX1 ) was constructed using multivariate Cox regression analysis and represented as a risk score. Overall survival (OS) probability was significantly lower in the high-risk group than in the low...
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (7): BSR20220251.
Published: 15 July 2022
...: Victory Ibigo Poloamina ( poloaminavictory@yahoo.com ) 10 02 2022 16 06 2022 22 06 2022 23 06 2022 acetylation/deacetylation acetyltransferases bioinformatics immunomodulation inflammation toll-like receptors Inflammation is central to many diseases such as cancer...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2022) 42 (1): BSR20211939.
Published: 28 January 2022
... BY) . bioinformatics CCNB2 diagnosis and prognosis biomarkers immune infiltrates Low-grade glioma The results of CCNB2 and expression in various cancers showed that compared with the normal tissues, the expression of CCNB2 increased in BLCA, BRCA, OV, GBM, UCEC and many other cancers, but only...
Articles
Jian Guan, Jinru Weng, Qiaosheng Ren, Chunbin Zhang, Liantao Hu, Wenjun Deng, Shizhen Lu, Xinyu Dong, Weidong Li, Yue Li, Weiqun Wang
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (12): BSR20212403.
Published: 22 December 2021
..., the mechanisms of CXCL3 in head and neck squamous cell carcinoma (HNSCC) remain unclear. In our study, multiple databases were used to explore the expression level, prognostic value, and related mechanisms of CXCL3 in human HNSCC through bioinformatic methods. We also performed further experiments in vivo...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (12): BSR-2021-0198_RET.
Published: 17 December 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics Human bone marrow mesenchymal stem cells Human umbilical...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (12): BSR20212026.
Published: 08 December 2021
... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics OV Platinum resistance Prognosis ZNF76 Ovarian cancer (OV) is the 7th most common cancer in women, with an estimated 239 000 new cases and 152 000 deaths worldwide annually [ 1 ]. The majority...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (12): BSR20212218.
Published: 07 December 2021
... ranking generated, that is a positive value if target genes are up-regulated in the dataset, or a negative value if target genes are down-regulated. Then, a normalized enrichment score (NES) is obtained for a particular subnetwork, considering the size of the subnetwork itself. bioinformatics...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (10): BSR20211429.
Published: 12 October 2021
...). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Atherosclerosis Bioinformatics Chinese Medicine Danggui Buxue Decoction Herb Medicine Integrated...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (10): BSR20211615.
Published: 12 October 2021
... pathology but would also help provide sensitive and efficient approaches for diagnosis and treatment. bioinformatics Brain metastasis tumor microenvironments Previous studies have documented that tumor BM is a complicated process, including steps such as the detachment of cells from the primary...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20210158.
Published: 28 July 2021
... 2021 15 07 2021 © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics Head and neck cancer Immune Prognosis...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20204301.
Published: 01 July 2021
... 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics immune-related genes pancreatic cancer prognostic model...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (7): BSR20210033.
Published: 01 July 2021
...Nese Unver The patterns of chemokine expression play a decisive role in both breast cancer prognosis and metastasis. In a recent article published in Bioscience Reports , ‘Bioinformatics identification of CCL8/21 as potential prognostic biomarkers in breast cancer microenvironment’, Chen et al...
Articles
Jinzhou Zheng, Wenhao Xu, Wangrui Liu, Haijia Tang, Jingen Lu, Kui Yu, Xiaoyun Song, Feng Li, Yu Wang, Rui Wang, Lili Chen, Hailiang Zhang, Yunhua Qiu, Gaomeng Wei, Xiqiu Zhou, Jianfeng Yang
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (6): BSR20204421.
Published: 10 June 2021
... in the Medical Institution of Fudan University Shanghai Cancer Center (Shanghai, China) and approved by the Animal Care and Use Committee (No. 2008222-xp49). bioinformatics Bu-Shen-Jian-Pi-Fang clear cell renal cell carcinoma glycolysis network pharmacology traditional Chinese medicine...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (5): BSR20210231.
Published: 21 May 2021
...′-GGAUAUAAGUACUGAAAUGTT-3′ siDLGAP5-3: 5′-GAAAGAGCAGAGAGAGAAATT-3′ bioinformatics DLGAP5 glioma LMNB1 prognosis proliferation Glioma is the most common primary cancer in the central nervous system. The 5-year survival rate of glioma patients is poor due to the invasive growth of the tumor...
Articles
Lulu Wang, Yongtao Li, Xiaodong Zhang, Na Liu, Shiyang Shen, Shizhu Sun, Yang Jiang, Penghui Li, Haifeng Jin, Lei Shen
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (5): BSR20210198.
Published: 20 May 2021
.... We used bioinformatics to predict these processes. In vitro , BMSCs were stimulated in a high-glucose (HG) environment with 50 or 100 μg/ml IL-8 was used as the IL-8 group. A total of 5 μmol/l Triciribine was added to the two IL-8 groups as the Akt inhibitor group. Cultured human umbilical vein...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (3): BSR20203235.
Published: 17 March 2021
... ) 09 09 2020 24 02 2021 09 03 2021 09 03 2021 © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203458.
Published: 12 January 2021
... under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics diagnostic indicator serum miRNAs stroke WGCNA Stroke, also known as cerebral vascular accident, is one of the most prevalent causes of death and long-term disability worldwide [ 1 , 2 ]. A comprehensive...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20202564.
Published: 08 January 2021
...Yali Wang; Kun Zheng; Xiuqiong Chen; Rui Chen; Yanmei Zou Background: The present study aimed to use bioinformatics tools to explore pivotal genes associated with the occurrence of gastric cancer (GC) and assess their prognostic significance, and link with clinicopathological parameters. We also...
Articles
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203459.
Published: 07 January 2021
... BY) . bioinformatics cancer tumor Thyroid cancer is not only the most common malignancy of the human endocrine system, accounting for ∼3% of the total incidence of systemic malignant tumors, but also one of the fastest growing malignant solid tumors. According to the histopathological classification system...
Articles
Chang-Kyu Oh, Yeji Ko, Jeong Jun Park, Hye Jin Heo, Junho Kang, Eun Jung Kwon, Ji Wan Kang, Yoonsung Lee, Kyungjae Myung, Jin Mo Kang, Dai Sik Ko, Yun Hak Kim
Journal:
Bioscience Reports
Biosci Rep (2021) 41 (1): BSR20203204.
Published: 06 January 2021
...@pusan.ac.kr ) © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . abdominal aortic aneurysm bioinformatics FRZB gene expression omnibus...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (11): BSR20201820.
Published: 17 November 2020
... This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics cancer immunology microRNA Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous solid...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20201012.
Published: 28 October 2020
... an immune-related gene (IRG) prognostic model in STAD using bioinformatics analysis. Methods: RNA sequencing data from healthy samples and samples with STAD, IRGs, and transcription factors were analyzed. The hub IRGs were identified using univariate and multivariate Cox regression analyses. Using the hub...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (10): BSR20200980.
Published: 13 October 2020
... ) 01 04 2020 17 09 2020 24 09 2020 05 10 2020 © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20201713.
Published: 18 September 2020
...), and cellular component (CC). Pathway analysis is a functional analysis that maps genes to Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. GO and KEGG analyses were performed using the online DAVID (The Database for Annotation, Visualization and Integrated Discovery) bioinformatics database ( https...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20193995.
Published: 16 September 2020
... and DEGs. bioinformatics H9c2 IGF1 miR-489 Myocardial infarction Myocardial infarction (MI) is a common and catastrophic cardiovascular disorder characterized by myocardial necrosis induced by long-term ischemia [ 1 ]. Acute MI (AMI) is the primary cause of cardiovascular disorders...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (9): BSR20202346.
Published: 16 September 2020
... gene; PAH, pulmonary arterial hypertension. Correspondence: Huan-Liang Wang ( wanghuanliang@email.sdu.edu.cn ) 25 06 2020 29 08 2020 02 09 2020 04 09 2020 Bioinformatics Computational biology Pulmonary Arterial Hypertension Transcriptomics Pulmonary...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR20200894.
Published: 28 August 2020
...Kaifei Zhao; Lin Xu; Feng Li; Jin Ao; Guojun Jiang; Rongshu Shi; Fang Chen; Qing Luo Background: Due to the heterogeneity of hepatocellular carcinoma (HCC), hepatocelluarin-associated differentially expressed genes were analyzed by bioinformatics methods to screen the molecular markers for HCC...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR20200963.
Published: 20 August 2020
... and GSE81558, were converted into differently expressed proteins. The STRING (Search Tool for the Retrieval of Interacting Genes) online database ( http://string-db.org ) could construct PPI network, which was visualized by Cytoscape (version 2.8) [ 25 ]. bioinformatics biomarker hub genes overall...
Includes: Supplementary data
Articles
Zhimin Ye, Jun Fang, Zhun Wang, Lei Wang, Bin Li, Tongxin Liu, Yuezhen Wang, Jianfeng Hua, FangZheng Wang, Zhenfu Fu
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR20201727.
Published: 20 August 2020
... 2020 13 07 2020 14 07 2020 © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics ceRNA core genes DEGs...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR20201555.
Published: 17 August 2020
... © 2020 The Author(s). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics key gene papillary thyroid carcinoma RNA-Seq...
Articles
Weichun Tang, Jie Li, Xinxia Chang, Lizhou Jia, Qi Tang, Ying Wang, Yanli Zheng, Lizhou Sun, Zhenqing Feng
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (8): BSR20201261.
Published: 07 August 2020
... the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics biological function hub genes Ovarian cancer prognostic model Ovarian cancer (OC) is the most lethal malignant disease in the female reproductive system, with over 200000 new cases and 150000 deaths each year worldwide [ 1...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20194429.
Published: 27 July 2020
... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics Biomarker Bladder cancer CDC20 therapeutics Bladder cancer (BC) is the ninth most common diagnostic cancer and the second most common...
Includes: Supplementary data
Articles
Xinrong Li, Yue Zhu, Maria Keaton, Ancha Baranova, Sha Liu, Xiaodong Hu, Qi Li, Long Cheng, Peng Zhou, Hongbao Cao, Yong Xu
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (7): BSR20201083.
Published: 21 July 2020
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics peroxisome proliferator-activated receptors psychotic disorders Schizophrenia (SCZ) is a mental illness with high heritability, characterized by abnormal behavior and a decreased...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (6): BSR-20181016_COR.
Published: 19 June 2020
... prognosis bioinformatics The authors of the original article above article “The effect of HMGB1 on the clinicopathological and prognostic features of cervical cancer” ( Bioscience Reports (2019) 39 , https://doi.org/10.1042/BSR20181016 ) would like to correct Figure 2 A, as the survivor curves...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (5): BSR20193377.
Published: 27 May 2020
... network generated under soft threshold was set as 9. After co-expression modules were simulated, top four modules significantly related to WHO grading were identified, top 20% representative genes in which were saved as result A. bioinformatics gene glioma Malignant gliomas are the most...
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (3): BSR20194255.
Published: 27 March 2020
... WNT10B might be valuable for anti-glioma research. The presumed direction was provided to explore the relation of WNTs signal and multiple pathways in glioma. bioinformatics expression glioma prognosis WNT IMB SPSS 22.0 and GraphPad Prism 7.0 software were used to analyze statistical data...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (3): BSR20200298.
Published: 20 March 2020
... in the cytokine production, a series Cytokine Antibody Arrays were performed to detect differentially expressed cytokines between control and HIP-55 knockdown cells. A total of 97 differentially expressed cytokines were identified from 300 cytokines in A549 cell. Bioinformatics analysis showed...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2020) 40 (2): BSR20192724.
Published: 25 February 2020
...). 2020 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Bioinformatics Head and neck cancer Immune cell prognosis TCGA Head and neck cancer (HNC...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (11): BSR20191511.
Published: 13 November 2019
... Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics Hub genes Neuropathic pain Peripheral nerve injury Neuropathic pain is one of the most frequent forms of pathological pain, and is normally induced by somatosensory system injury...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (7): BSR20191612.
Published: 29 July 2019
... Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics biomarker head and neck squamous cell carcinoma prognosis PYGM TNNC2 Head and neck squamous cell carcinoma (HNSCC) ranks as the sixth most...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20182172.
Published: 31 May 2019
...-like receptor (NLR) signaling pathway. qPCR showed the same expression trend of hub gene ACLY as in our bioinformatics analysis. Conclusion : Bioinformatics analysis revealed that ACLY and the pathways involved are possible target in the molecular mechanism of type 2 diabetes. Correspondence...
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20181514.
Published: 17 May 2019
... circRNAs between the tumour tissues and paracancerous tissues of three osteosarcoma patients. Bioinformatics analysis was used to analyse their potential functions. Five differentially expressed circRNAs were selected to detect the relative expression level in tumour and paracancerous tissues of ten...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20182109.
Published: 14 May 2019
... the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics colon cancer cell apoptosis cell cycle molecular docking Tetrandrine Tetrandrine (Tet), bisbenzylisoquinoline alkaloids isolated from Stephania tetrandra and other related species of Menispermaceae , is considered...
Articles
Beata Gajda-Deryło, Thomas Stahnke, Stephan Struckmann, Gregor Warsow, Kerstin Birke, Marco T. Birke, Bettina Hohberger, Robert Rejdak, Georg Fuellen, Anselm G. Jünemann
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (5): BSR20181894.
Published: 02 May 2019
... Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics ophthalmology protein expression Glaucoma is the second leading cause of irreversible blindness worldwide [ 1 ]. It is a neurodegenerative disease accompanied by the degeneration of retinal...
Includes: Supplementary data
Articles
Liuhong Zheng, Yuhan Zhang, Yajun Fu, Hangdi Gong, Jianjun Guo, Kangjing Wu, Qiaojun Jia, Xianfeng Ding
Journal:
Bioscience Reports
Biosci Rep (2019) 39 (2): BSR20181284.
Published: 15 February 2019
... of bioinformatics prediction with experimental verifications indicated that lncRNA MALAT1 can regulate BLCAP mRNA expression through binding to miR-339-5p. Correspondence: Xianfeng Ding ( xfding@zstu.edu.cn ) 28 07 2018 09 01 2019 16 01 2019 25 01 2019 © 2019 The Author(s). 2019...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (6): BSR20181178.
Published: 07 December 2018
... Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . bioinformatics GINS hepatocellular carcinoma prognosis survival High-fidelity genomic DNA replication is important to all forms of cellular life and requires...
Includes: Supplementary data
Articles
Journal:
Bioscience Reports
Biosci Rep (2018) 38 (2): BSR20171208.
Published: 21 March 2018
... in vascular endothelial injury. It is an important factor in the development of diabetes mellitus (DM). The aim of the present study was to screen out the potential candidate microRNAs (miRNAs) in DM patients with BSS by high-throughput sequencing (HTS) and bioinformatics analysis. Human umbilical vein...
Articles
Journal:
Bioscience Reports
Biosci Rep (2017) 37 (5): BSR20170844.
Published: 17 October 2017
... BY) . bioinformatics knee osteoarthritis rs187084 polymorphism Toll-like receptor 9 Osteoarthritis (OA) is a degenerative joint disease characterized by joint destruction with cartilage loss and occasional gross derangement of joint integrity [ 1 ]. Knee osteoarthritis (KOA) causes the most severe economic...
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