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Keywords: Wnt
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Biosci Rep (2020) 40 (3): BSR20194255.
Published: 27 March 2020
...Anqi Xu; Huiping Yang; Kunjie Gao; Zhengming Zhan; Zibin Song; Tengyue Huang; Ye Song Aims: The dysregulation and essential role of WNTs in glioma have been widely implicated. However, there is a paucity of literature on the expression status of all the 19 WNTs in glioma. Our study was aimed...
Includes: Supplementary data
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Biosci Rep (2020) 40 (3): BSR20193353.
Published: 06 March 2020
... chemotherapeutic agents do not increase the survival rate in patients with unresectable CCA. Accordingly, there is a need to identify new therapeutic agents for the effective management of intra- and extra-hepatic CCA. Clinical as well as preclinical studies have suggested the key role of the activation of Wnt/β...
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Biosci Rep (2019) 39 (9): BSR20192466.
Published: 24 September 2019
...Ying-Li Sha; Shuang Liu; Wen-Wen Yan; Bo Dong Hepatoblastoma is a malignant tumor in the liver of children that generally occurs at the age of 2–3 years. There have been ample evidence from the preclinical as well as clinical studies suggesting the activation of Wnt/β-catenin signaling...
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Biosci Rep (2016) 36 (6): e00427.
Published: 09 December 2016
... that Wnt proteins are up-regulated during intimal thickening, and have speculated that these lead to activation of downstream genes with β-catenin/T-cell factor (TCF)-responsive promoters. In the present study, we aimed to provide evidence that β-catenin/TCF signalling promotes neointima formation...
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Biosci Rep (2014) 34 (5): e00142.
Published: 17 October 2014
...Jia Yu; David M. Virshup In the three decades since the discovery of the Wnt1 proto-oncogene in virus-induced mouse mammary tumours, our understanding of the signalling pathways that are regulated by the Wnt proteins has progressively expanded. Wnts are involved in an complex signalling network...