...Mian Liu; Jiu Yang; Wuwu Lv; Shuanglian Wang; Tao Du; Kejing Zhang; Yuhui Wu; Xueping Feng Due to the lack of known therapeutic targets for triple-negative breast cancer (TNBC), chemotherapy is the only available pharmacological treatment. Pirarubicin (tetrahydropyranyl Adriamycin, THP) is the most...

...Yomna S. Abd El-Aziz; Andrew J. Spillane; Patric J. Jansson; Sumit Sahni Triple-negative breast cancer (TNBC) is a group of breast cancers which neither express hormonal receptors nor human epidermal growth factor receptor. Hence, there is a lack of currently known targeted therapies and the only...

...Limin Niu; Qingxia Fan; Min Yan; Liuxing Wang NRON mediates the degradation of tat protein to participate in HIV-1 infection. Interestingly, our study observed the down-regulation of NRON in triple-negative breast cancer (TNBC) tissues compared with paired adjacent healthy tissues. In contrast...

...Weiyang Tao; Chunyang Wang; Bifa Zhu; Guoqiang Zhang; Da Pang Breast cancer, the most frequently occurring malignant tumor, has high mortality rate, especially triple-negative breast cancer (TNBC). LncRNA-differentiation antagonizing non-protein coding RNA (lncRNA DANCR) has been found that its...

...Yuqing Wen; Gongpeng Dai; Liping Wang; Kanda Fu; Shuguang Zuo Background: Radiotherapy is an important locoregional treatment, and its effect on triple-negative breast cancer (TNBC) needs to be enhanced. The aim of the present study was to investigate the potential effects of XRCC4...

...Naveen K.R. Chalakur-Ramireddy; Suresh B. Pakala TNBC (Triple Negative Breast Cancer) is a subtype of breast cancer with an aggressive phenotype which shows high metastatic capability and poor prognosis. Owing to its intrinsic properties like heterogeneity, lack of hormonal receptors and aggressive...