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Biosci Rep (2022) 42 (9): BSR-2019-4030_RET.
Published: 14 September 2022
... and distributed under the Creative Commons Attribution License 4.0 (CC BY) . Dexmedetomidine EX527 mTOR Myocardial ischemia/reperfusion SIRT1 ...
Biosci Rep (2022) 42 (7): BSR-2019-4030_EOC.
Published: 27 July 2022
... Attribution License 4.0 (CC BY) . Dexmedetomidine EX527 mTOR Myocardial ischemia/reperfusion SIRT1 ...
Biosci Rep (2020) 40 (10): BSR20200092.
Published: 13 October 2020
... and repressed acinar cell apoptosis. Notably, mechanistic studies revealed that CTRP3 overexpression suppressed NF-κB p65 phosphorylation and p53 acetylation to alleviate cerulein-induced SAP in mouse models through activation of silent information regulator 1 (SIRT1), a nicotinamide adenine dinucleotide...
Biosci Rep (2020) 40 (6): BSR20191908.
Published: 22 June 2020
...: The expression of miR-122, silent information regulator 1 (SIRT1), collagen II, aggrecan, matrix metalloproteinase (MMP) 13 (MMP13) and ADAMTS4 in OA cartilage was detected by RT-qPCR. Target gene prediction and screening, luciferase reporter assay were used to verify downstream target genes of miR-122. Results...
Biosci Rep (2020) 40 (5): BSR20194030.
Published: 27 May 2020
... of Dex in MI/R injury via the silent information regulator factor 2-related enzyme 1 (SIRT1)/mammalian target of rapamycin (mTOR) signaling pathway. First, Dex was immediately injected into rat models of MI/R injury during reperfusion. After Evans Blue-triphenyl tetrazolium chloride (TTC) and Hematoxylin...
Biosci Rep (2020) 40 (1): BSR20192121.
Published: 21 January 2020
.... Astragalus polysaccharides (APS) has been long used as a traditional Chinese medicine in treating diabetes. In the present study, the preventive effects and mechanisms of APS on metabolic memory-induced RPE cell death were investigated. Methods: The expressions of miR-204 and SIRT1 were determined by reverse...
Includes: Supplementary data
Biosci Rep (2019) 39 (1): BSR20180902.
Published: 03 January 2019
...Ping Sun; Jun-Bo Yin; Li-Hua Liu; Jian Guo; Sheng-Hai Wang; Chun-Hui Qu; Chun-Xia Wang The aim of the present study was to understand the possible role of the Dihydromyricetin (DHM) in Alzheimer’s disease (AD) rat model through regulation of the AMPK/SIRT1 signaling pathway. Rats were divided...
Includes: Supplementary data
Biosci Rep (2018) 38 (6): BSR20181139.
Published: 21 December 2018
...Xun Wang; Bing Wang; Jianping Zhao; Caixing Liu; Xianpeng Qu; Yuhuan Li Major depressive disorder (MDD) is a common mood disorder, and the treatment of MDD requires a variety of biopsychosocial approaches. The role of Silent information regulator 1 (SIRT1) in the regulation of MDD has recently been...
Sheng-lan Gao, Ya-hong Wang, Chun-yan Li, La-wei Yang, Bao-an Zou, Zu-guang Chen, Wei-min Yao, Ze-qing Song, Jun-fen Cheng, Zi-ying Lin, Gang Liu
Biosci Rep (2018) 38 (4): BSR20180410.
Published: 18 July 2018
...Sheng-lan Gao; Ya-hong Wang; Chun-yan Li; La-wei Yang; Bao-an Zou; Zu-guang Chen; Wei-min Yao; Ze-qing Song; Jun-fen Cheng; Zi-ying Lin; Gang Liu Cathepsin S (CTSS) and Sirtuin-1 (SIRT1) played crucial roles in the pathogenesis of chronic obstructive pulmonary disease (COPD). However...