... respiratory distress syndrome. In addition, we aim to review the planning and analysis of clinical trials on exogenous surfactant therapy for COVID-19. SARS-CoV-2 is thought to target alveolar type-II cells, the lung cells in charge of producing surfactant, similar to SARS-CoV. Inflamed cells emit...

...Arpana Parihar; Shivani Malviya; Raju Khan; Ajeet Kaushik; Ebrahim Mostafavi The present severe acute respiratory syndrome-2 (SARS-CoV-2) mediated Coronavirus pandemic (COVID-19) and post-COVID-19 complications affect human life drastically. Patients who have been cured of COVID-19 infection...

...Ziyuan Wang; Minghui Yang; Xi Chen; Rongxin Xiao; Yu Dong; Ming Chu; Guojie Song; Yuedan Wang The pandemic of coronavirus disease 2019 (COVID-19) by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still underway. Due to the growing development of severe symptoms, it is necessary...

...Vipul Kumar; Anissa Nofita Sari; Hazna Noor Meidinna; Jaspreet Kaur Dhanjal; Chandru Subramani; Brohmomoy Basu; Sunil C. Kaul; Sudhanshu Vrati; Durai Sundar; Renu Wadhwa Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has...

...Vipul Kumar; Anissa Nofita Sari; Hazna Noor Meidinna; Jaspreet Kaur Dhanjal; Chandru Subramani; Brohmomoy Basu; Sunil C Kaul; Sudhanshu Vrati; Durai Sundar; Renu Wadhwa COVID-19 pandemic caused by SARS-CoV-2 virus has become a global health emergency. Although new vaccines have been generated...

...Mohammad Tohidul Amin; Kaniz Fatema; Sayema Arefin; Fahad Hussain; Dipty Rani Bhowmik; Mohammad Salim Hossain An influenza-like virus named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for COVID-19 disease and spread worldwide within a short time. COVID-19 has now...

...Rajesh Ahirwar; Sonu Gandhi; Komal Komal; Geeta Dhaniya; Prem Prakash Tripathi; Vyas Madhavrao Shingatgeri; Krishan Kumar; Jai Gopal Sharma; Saroj Kumar Coronavirus disease 2019 (COVID-19) is a life-threatening respiratory infection caused by severe acute respiratory syndrome virus (SARS-CoV-2...

...Kourosh H. Ebrahimi; James S.O. McCullagh The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which started in late 2019, has caused huge social and economic losses. A growing number of investigators are focusing on understanding the interaction of SARS-CoV-2...

... by a novel coronavirus (SARS-CoV-2), which lead to severe complications that worsen the prognosis in these subjects. Increasing evidence implicate Heparan sulfate proteoglycans (HSPGs) and Heparanase in various diseases and pathologies, including hypercoagulability states. Moreover, HSPGs and Heparanase...

...Mateus S.M. Serafim; Jadson C. Gertrudes; Débora M.A. Costa; Patricia R. Oliveira; Vinicius G. Maltarollo; Kathia M. Honorio Since the emergence of the new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) at the end of December 2019 in China, and with the urge of the coronavirus...

...Junfang Wu; Mingming Zhao; Chenze Li; Yuxuan Zhang; Dao Wen Wang The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has induced an ongoing global health crisis. Here we utilized a combination of targeted amino acids (AAs) and clinical biochemical profiling to analyze the plasma...

... by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . COVID-19 differential analysis high-resolution mass spectrometry lipidomics SARS-CoV-2 High lipidomic coverage was achieved by untargeted lipidomics...

... items were used: ‘glucose control’, ‘glucose’, ‘glycemic’, ‘HbA1c’, ‘coronavirus’, ‘SARS’, ‘2019 novel coronavirus’, ‘COVID-19’ and ‘SARS-CoV-2’. Additional papers were identified by manually searching and citation tracking. Two reviewers (Y.Y. and Z.C.) independently reviewed all the included...

...Sarbashri Bank; Subrata Kumar De; Biswabandhu Bankura; Smarajit Maiti; Madhusudan Das; Gausal A Khan The outbreak of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a global catastrophe. The elderly and people with comorbidity are facing a serious complication of the disease...

... reports have enough evidence for the use of FDA-approved drugs which have inhibitory potential against target proteins of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Here, we utilized a structure-based drug design approach to find possible drug candidates from the existing pool of FDA...