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Keywords: Rheumatoid arthritis
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Biosci Rep (2022) 42 (4): BSR20211392.
Published: 21 April 2022
...Bharti Rakhecha; Prachi Agnihotri; Tikam Chand Dakal; Mohd Saquib; Monu; Sagarika Biswas Objectives: Rheumatoid arthritis (RA) is an autoimmune disease, associated with chronic inflammation of synoviocytes. Tumor necrosis factor α (TNF-α) plays a crucial role in the pathogenesis of RA through pro...
Includes: Supplementary data
Biosci Rep (2021) 41 (7): BSR-2018-2500_RET.
Published: 28 July 2021
... © 2021 The Author(s). 2021 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . fibroblast-like synoviocytes miR-506 Rheumatoid arthritis This article...
Biosci Rep (2020) 40 (12): BSR20193823.
Published: 16 December 2020
...Bin Zuo; JunFeng Zhu; Fei Xiao; ChengLong Wang; Yun Shen; XiaoDong Chen Background: Rheumatoid arthritis (RA) and osteoarthritis (OA) are two major types of joint diseases. The present study aimed to identify hub genes involved in the pathogenesis and further explore the potential treatment targets...
Includes: Supplementary data
Biosci Rep (2020) BSR20201735.
Published: 03 December 2020
.... Rheumatoid arthritis methotrexate miR-22 inflammatory reactions apoptosis WITHDRAWN ARTICLE WITHDRAWN: Lipid nanoparticles co-loaded with miRNA-22 and methotrexate for enhanced anti-inflammatory response in rheumatoid arthritis Hao Yuan; Ya-Meng Peng; Zhen-Yi Long; Si-Xian Wu; Yi-Feng Zhou Biosci Rep...
Biosci Rep (2020) 40 (9): BSR20201713.
Published: 18 September 2020
...Zhaoyan Li; Meng Xu; Ronghang Li; Zhengqing Zhu; Yuzhe Liu; Zhenwu Du; Guizhen Zhang; Yang Song Objectives: Rheumatoid arthritis (RA) is the most common inflammatory arthritis in the world, but its underlying mechanism is still unclear. The present study aims to screen and verify the potential...
Biosci Rep (2020) 40 (9): BSR20194515.
Published: 18 September 2020
... that the autophagy linked with TNF-α-induced apoptosis in response to rheumatoid arthritis. The results of the AIA rat model experiment presented that FVH1-1 can reduce the degree of joint swelling and inflammatory factors to a certain extent in vivo . The Luria–Bertani (LB) medium containing 1% tryptone, 1...
Biosci Rep (2020) 40 (8): BSR20201273.
Published: 18 August 2020
...Shanshan Yang; Wei Yin; Yan Ding; Fan Liu Backgrounds: Rheumatoid arthritis (RA) is a frequent autoimmune disease. Emerging evidence indicated that ZNFX1 antisense RNA1 (ZFAS1) participates in the physiological and pathological processes in RA. However, knowledge of ZFAS1 in RA is limited...
Biosci Rep (2020) 40 (8): BSR-20191136_RET.
Published: 04 August 2020
..., alerting the Editorial Board to manipulation in Figure 8C. Rheumatoid arthritis microRNA-101-3p Prostaglandin-endoperoxide synthase 2 Fibroblast-like synoviocytes Synovial injury ...
Biosci Rep (2020) 40 (4): BSR20193160.
Published: 03 April 2020
... expressed in many types of diseases. The present study aimed to determine the circRNAs specifically expressed in peripheral blood mononuclear cells (PBMCs) from rheumatoid arthritis (RA) patients to identify their possible molecular mechanisms. Methods: To identify the circRNAs specifically expressed in RA...
Includes: Supplementary data
Biosci Rep (2020) 40 (1): BSR20191136.
Published: 14 January 2020
...Qiaofeng Wei; Fang Lv; Hongju Zhang; Xinfang Wang; Qin Geng; Xiuying Zhang; Tongying Li; Shujun Wang; Yajuan Wang; Yanhui Cui Objective: Rheumatoid arthritis (RA) is the most frequently occurring inflammatory arthritis. The present study was performed to characterize the role of microRNA-101-3p...
Biosci Rep (2020) 40 (1): BSR20191449.
Published: 06 January 2020
...Menglei Yu; Jingyi Hou; Minghui Zheng; Yi Cao; Yamuhanmode Alike; Yuanyuan Mi; Jie Zhu Interleukin-21 (IL-21) is a cytokine that plays a crucial role in pathogenesis and activity of the rheumatoid arthritis (RA). Meanwhile, genetic polymorphisms in the IL-21 gene may alter its expression. Previous...
Biosci Rep (2019) 39 (12): BSR20192009.
Published: 28 November 2019
...Yan Zhang; Ni Yan; Xiaoqing Wang; Yanhai Chang; Yu Wang It is reported that miR-129-5p plays an important role in various diseases, but its effect on rheumatoid arthritis (RA) and the potential mechanism remain to be clarified. In the present research, we aimed to investigate the effect of miR-129...
Biosci Rep (2019) 39 (9): BSR20182263.
Published: 03 September 2019
...Nanwen Zhang; Zhiwei Liu; Hongbin Luo; Weifang Wu; Kaimei Nie; Lin Cai; Shuangyu Tan; Xiaole Chen; Ying Huang; Jiaxing Liu; Meina Lv; Xin Zhang; Yun Fan; Yuying Lin; Shennan Ye; Yang Liu; Lixian Wu; Jianhua Xu Background: Rheumatoid arthritis (RA) is a chronic articular synovial inflammatory...
Biosci Rep (2019) 39 (8): BSR20190110.
Published: 15 August 2019
...Kewei Ren; Jilei Tang; Luming Nong; Nan Shen; Xiaolong Li Controversial results concerning the association between a polymorphism rs6822844 in the interleukin (IL) 21 (IL-21) gene and rheumatoid arthritis (RA) have existed. A meta-analysis to confirm above relationships is necessary to be performed...
Biosci Rep (2019) 39 (7): BSR20182192.
Published: 26 July 2019
... arthritis (RA). MiRNAs are closely involved in a variety of pathologic conditions. In the present study, we aimed to screen for the aberrant expression of miRNAs in rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) to further identify the altered expression of miR-26a-5p in RA-FLS...
Includes: Supplementary data
Biosci Rep (2019) 39 (6): BSR20190188.
Published: 28 June 2019
...Zongqiang Gao; Chen Duan; Fang-fang Yu; Xiong Guo Kashin–beck disease (KBD) is endemic chronic osteoarthrosis and its pathogenesis is still unclear. The present study aimed to explore differential gene expression in articular cartilage between patients with rheumatoid arthritis (RA) and KBD...
Biosci Rep (2019) 39 (5): BSR20182500.
Published: 07 May 2019
...Dan Li; Qingchen Zhou; Gaojian Hu; Gang Wang Fibroblast-like synoviocytes (FLSs) play a crucial role in rheumatoid arthritis (RA) pathogenesis. While miRNA (miR)-506 has been implicated in the progression of multiple diseases, its role in RA remains to be explored. The present study evaluated...
Biosci Rep (2019) 39 (5): BSR20182374.
Published: 02 May 2019
...Guan Wang; Lian Tang; Xihai Zhang; Yao Li IL-6 produced by human fibroblast-like synoviocytes (HFLS) promotes rheumatoid arthritis (RA), while lncRNA DILC regulates liver cancer stem cells by inhibiting IL-6. Therefore, lncRNA DILC may participate in RA. In the present study, we found that plasma...
Biosci Rep (2019) 39 (1): BSR20180890.
Published: 08 January 2019
...Kai Liu; Yingang Zhang; Liang Liu; Qiling Yuan The present study aimed to explore miR-125 effects on rheumatoid arthritis (RA) development to provide a potential target for RA. Briefly, rat RA model was established (Model group) by injection of Freund’s Complete Adjuvant into the left hind toe...
Biosci Rep (2018) 38 (6): BSR20180982.
Published: 14 November 2018
...Yufan Wangyang; Linhong Yi; Tao Wang; Yanbo Feng; Guangwang Liu; Dongya Li; Xin Zheng Background Fibroblast-like synoviocytes (FLSs) that line the intimal synovium play a crucial role in the pathogenesis of rheumatoid arthritis (RA). miR-199a-3p is a highly conserved miRNA that has been shown...
Biosci Rep (2018) 38 (5): BSR20180626.
Published: 05 October 2018
...Guoqing Li; Ying Liu; Fanru Meng; Zhongbin Xia; Xia Wu; Yuxuan Fang; Chunwang Zhang; Dan Liu Rheumatoid arthritis (RA) is a common chronic autoimmune joint disease characteristic of elevated proliferation and infiltration of fibroblast-like synoviocytes (FLS). Here, we aimed to explore...
Includes: Supplementary data
Biosci Rep (2018) 38 (4): BSR20180540.
Published: 31 July 2018
...Zhongbin Xia; Fanru Meng; Ying Liu; Yuxuan Fang; Xia Wu; Chunwang Zhang; Dan Liu; Guoqing Li Background: Rheumatoid arthritis (RA) is a inflammatory disease that characterized with the destruction of synovial joint, which could induce disability. Inflammatory response mediated the RA. It has been...
Biosci Rep (2018) 38 (3): BSR20180541.
Published: 21 June 2018
...Guoqing Li; Zhongbing Xia; Ying Liu; Fanru Meng; Xia Wu; Yuxuan Fang; Chunwang Zhang; Dan Liu Rheumatoid arthritis (RA) is an autoimmune disease of the joints characterized by synovial hyperplasia and chronic inflammation. Fibroblast-like synoviocytes (FLS) play a central role in RA initiation...