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Gabriela Assis-de-Lemos, Jamila Monteiro, Viviane M. Oliveira-Valença, Guilherme A. Melo, Ricardo A. de Melo Reis, Stevens K. Rehen, Mariana S. Silveira, Antonio Galina
Biosci Rep (2021) 41 (12): BSR20211191.
Published: 08 December 2021
... involved in the pathophysiology of psychiatric disorders. Neurodevelopment is modulated in multiple steps by reactive oxygen species (ROS), byproducts of oxidative metabolism that are signaling factors involved in proliferation, differentiation, and migration. Hexokinase (HK), when associated...
Includes: Supplementary data
Biosci Rep (2020) 40 (8): BSR20201807.
Published: 18 August 2020
... and increased intracellular reactive oxygen species (ROS) level. p53 knockdown attenuated Tan IIA-induced lipid peroxidation and ferroptosis. Tan IIA also induced lipid peroxidation and ferroptosis in BGC-823 xenograft model, and the anti-cancer effect of Tan IIA was attenuated by Fer-1 in vivo . Therefore, Tan...
Biosci Rep (2019) 39 (12): BSR20192368.
Published: 16 December 2019
... species (ROS) in in vitro model. ROS reduced the effect of Gal-3 on oxidative stress in in vitro model. Down-regulating the content of TXNIP decreased the effect of Gal-3 on neuroinflammation in in vitro model. Suppressing the level of NLRP3 could weaken the effect of Gal-3 on neuroinflammation...
Biosci Rep (2019) 39 (5): BSR20180268.
Published: 21 May 2019
... for SLC34A2-induced EZH2 expression. Reactive oxygen species (ROS) generation contributed to the stabilization of HIF-1α by leading to the binding of HIF-1α to the EZH2 promoter, which resulted in increased EZH2 expression. Additionally, we showed that the inhibition of both HIF-1α expression and ROS...
Includes: Supplementary data
Biosci Rep (2019) 39 (5): BSR20190371.
Published: 14 May 2019
... immunosenescence immunological memory inflammation ROS The bone marrow (BM) is renowned for hematopoiesis, the formation of the cellular components that comprise our blood, but it has also been described as the preferred site for the maintenance and survival of long-living immune cells [ 1 , 2 ]. Over...
Biosci Rep (2018) 38 (6): BSR20181065.
Published: 18 December 2018
..., migration, invasion and apoptosis. The growth, migration and invasion rate of UHRF1 knockdown cells was lower than that of the control. Moreover, ROS generation and caspase-3/caspase-9 activities increased in UHRF1 knockdown cells. And mitochondrial membrane potential decreased in UHRF1 knockdown cells...
Ana Caroline P. Gandara, José Henrique M. Oliveira, Rodrigo D. Nunes, Renata L.S. Goncalves, Felipe A. Dias, Fabio Hecht, Denise C. Fernandes, Fernando A. Genta, Francisco R.M. Laurindo, Marcus F. Oliveira, Pedro L. Oliveira
Biosci Rep (2016) 36 (2): e00321.
Published: 15 April 2016
... in the release of large quantities of amino acids, together with the haemoglobin prosthetic group, haem, which decomposes hydroperoxides and propagates oxygen-derived free radicals. Our previous studies demonstrated that reactive oxygen species (ROS) levels were diminished in the mitochondria and midgut...
Biosci Rep (2007) 27 (1-3): 165–171.
Published: 13 June 2007
... disorders are also reported. © 2007 The Biochemical Society 2007 Mitochondria Stem cells Differentiation Mitochondrial localization ROS MNGIE MINI REVIEW The Role of Mitochondria in Stem Cell Biology Claudia Nesti Æ Livia Pasquali Æ Francesca Vaglini Æ Gabriele Siciliano Æ Luigi Murri...