..., only the Tunisian and Moroccan populations were investigated. Our aim is to assess the association between APOA5 gene variant (rs662799) and haplotypes with MetS in Tunisian population and to perform a meta-analysis in North Africa. A total of 594 Tunisian participants were genotyped for polymorphism...

...Jing Liu; Guang Song; Ge Zhao; Tao Meng Background: It is well known that insulin-like growth factor 2 mRNA-binding protein 2 ( IGF2BP2 ) rs4402960 polymorphism is associated with Type 2 diabetes mellitus, which has a shared genetic background with gestational diabetes mellitus (GDM). Previous...

...Weicheng Duan; Chenlu Xia; Kang Wang; Yijie Duan; Ping Cheng; Bo Xiong Backgroud: Pre-eclampsia (PE) is a common pregnancy-induced hypertension disease. Some case–control studies reported the association between vascular endothelial growth factor (VEGF) gene polymorphisms (rs3025039, rs2010963...

...Hongwei Yan; Yuxiao Hong; Yunfei Cai Objectives: FAS plays a critical role in the extrinsic apoptosis pathway in autoimmune diseases. Previous studies investigating the association between FAS gene −670 A/G and −1377 G/A polymorphisms and the risk of autoimmune diseases reported controversial...

...Zheng Lian; Su-Fang Li; Yu-Xia Cui; Man-Yan Wu; Li-Na Su; Dan Hu; Wei-Jue Xiong; Hong Chen Background: Previous studies have explored associations between interleukin-18 (IL-18) promoter polymorphisms and coronary artery disease (CAD). However, the results were controversial. We conducted a meta...

...Yingqi Xiao; Hui Liu; Li Chen; Yang Wang; Xiang Yao; Xiaolian Jiang Objective: To investigate whether microRNAs genes’ polymorphisms are associated with arthritis. Methods: The PubMed, Cochrane Library et al. were systematically searched to identify case–control studies, systematic reviews and meta...

...Chunlei Zhou; Yingzi Tang; Jinhong Zhu; Lili He; Jinghang Li; Yizhen Wang; Haixia Zhou; Jing He; Haiyan Wu Neuroblastoma is one of the most common malignancy in childhood, which originates from the developing sympathetic nervous system. Single nucleotide polymorphisms (SNPs) in primary miRNA (pri...

...Yang Yang; Mengxue Fei; Xinying Zhou; Yuejun Li; Dadi Jin Objective: The present study was conducted for exploring the influence of fibroblast growth factor 2 receptor ( FGFR2 ) gene polymorphisms on osteoporosis occurrence risk in the Chinese population. Methods: Polymerase chain reaction...

...Wei Huang; Ruiyun Zhou; Jianfeng Li; Jianjun Wang; Hongwei Xiao The aim of the present study was to investigate the association of TNF-α-308 and TNF-α-238 gene polymorphisms with the risk of bone-joint and spinal tuberculosis (TB) by meta-analysis. By searching PubMed, Web of Science, Wanfang...

... and genetic markers are still required for early diagnosis. Toll-like receptor 4 (TLR4) is an essential player in inflammation in various diseases. However, the TLR4 polymorphisms have not been completely elucidated in both types of glaucoma. The aim of the present study was to identify the association...

... and GSPT2 . Recent studies have indicated that eRF3b involved in the development and proliferation of HepG2 cell, and eRF3a may be associated with tumor susceptibility. Based on this, we tested the effects of GSPT1 and GSPT2 single-nucleotide polymorphisms for all major Hepatitis B virus (HBV) outcomes...

...Wei Zhu; Hailang Liu; Xinguang Wang; Jinjin Lu; Huiping Zhang; Shaogang Wang; Weimin Yang Background. The results of previous studies on the association between polymorphisms of CYP1A1 and CYP1B1 and prostate cancer (PCa) susceptibility are inconsistent. The aim of the present study was to conduct...

...Narttaya Chaiwiang; Teera Poyomtip Background and objective: The hepatitis C virus (HCV) is able to cause a life-threatening disease relating to lethal hepatocellular carcinoma. Previous, Toll-like receptor polymorphisms were proposed as promising biomarker for HCV-related hepatocellular carcinoma...

...Ge Zhao; Yunfei Cai; Jing Liu; Tao Meng This meta-analysis was performed in order to determine the associations between the estrogen receptor α (ESR1) gene PvuII site (-397T/C, rs2234693) and XbaI site (-351A/G, rs9340799) polymorphisms with severe and mild pre-eclampsia. Eligible studies were...

...Jing He; Guoyan Xie; Hui Wu; Song Xu; Jun Xie; Youyuan Chen; Xinqian Zhao In the present study, we investigated the association of 12 polymorphisms in six inflammatory-response genes ( TNF, IL6, IL10, IL18, NFKB1 and NFKBIA ) with risk of acute kidney injury (AKI) in children. The polymorphisms...

...Xin Huang; Weiyue Zhang; Zengwu Shao Several studies have suggested that long non-coding RNA (lncRNA) gene polymorphisms are associated with cancer risk. In the present study, we conducted a meta-analysis related to studies on the association between lncRNA single-nucleotide polymorphisms (SNPs...